TxNxM1: The Anatomy and Clinics of Metastatic Cancer / Edition 1

by J.M. Debois

Overview

Although distant metastases are the most dreaded situation in the evolution of cancer of every organ, the medical literature has surprisingly given little attention to the anatomical relationship between the primary tumor and metastasic sites. Only risk factors, treatment possibilities, and survival results are extensively examined.

Stimulated by the occurrence in his practice of some puzzling and unexpected metastases, the author reviewed more than 12,000 references. He looked for anatomical relationships highlighting the relation between the location of the primary tumors and the particular patterns of metastasis observed. It would seem that the ‘pathways and flows' are apparently a more decisive factor in the implantation of the metastases than the ‘seed and soil' properties of the cancer cells and the metastatic site.

Aided by his colleague Dr. T. Geukens, M.D., the author includes original anatomical drawings, illustrating the sometimes unexpected pathways the cancer cells follow in order to reach the organs where they will become lodged and give rise to metastatic tumors. The subject has apparently not been exhausted in the literature and several ideas are given for further research.

Product Details

ISBN-13:	9780792367932
Publisher:	Springer Netherlands
Publication date:	02/28/2002
Edition description:	2002
Pages:	757
Product dimensions:	8.27(w) x 10.98(h) x 0.06(d)

About the Author

Dr. J.M. Debois is a retired radiation oncologist with forty years of academic and private practice. He has published two other books and more than a hundred articles, of which several appeared in peer-reviewed periodicals, case reports and reviews.

Table of Contents

The Metastasis and its Primary.- Metastases to the Thorax.- Metastases to the Abdominal Organs.- Metastases to the Digestive Tract.- Metastases to the Urogenital System.- Metastases to the Central Nervous System.- Metastases to the Head and Neck.- Metastases to the Skin, Soft-Tissues and Bone.- The Primary and its Metastases.- Metastases from Thoracic Tumors.- Metastases from Tumors of the Digestive Tract.- Metastases from Cancers of the Abdominal Organs.- Metastases from Cancers of the Urogenital Tract.- Metastases from Tumors of the Central Nervous System.- Metastases from Tumors of the Head and Neck.- Metastases from Tumors of the Skin, Soft-Tissue and Bone.

Editorial Reviews

Reviewer: Athanassios Argiris, MD (Northwestern University Feinberg School of Medicine)
Description: This eye-catching book deals exclusively with the metastatic spread of malignancy. Each organ that may harbor metastatic malignancy is examined; the author conducts a comprehensive review of all potential primary tumors that metastasize to a particular site (metastasis to). Anatomical and pathological background as well as the clinical presentation of patients with metastatic tumors is covered. In the second part of the book, a reverse analysis is conducted, and each primary tumor site is reviewed for its potential for metastases to various organs (metastatic from).
Purpose: The knowledge of metastatic patterns is fundamental to the practice and science of oncology. During his career the author has been intrigued by the metastatic potential of tumors. In this book, he focuses on the incident, symptoms, pathology, diagnosis, and imaging associated with metastatic sites. The goal is to make the clinician aware of all possibilities of metastasis and of the problems that are generated by it. Common as well as unexpected locations of metastatic spread are covered.
Audience: The audience for this book can be broad and can encompass any member of the multidisciplinary team involved in the management of cancer.
Features: Each chapter contains detailed enumeration of various studies, mainly case series, which have reported the incidence of metastases from or to various sites. The first part of the book concerns organs and sites where tumor cells metastasize, to answer the question, "Where is the primary organ?" when a metastatic focus is identified. Metastatic sites covered include the thoracic, abdominal, and head and neck organs as well as the nervous system, bones, lymph nodes, and others. The second part reviews the metastatic potential of each primary organ asking the question, "Where do tumors metastasize?" This book contains encyclopedic knowledge that maybe useful to clinical oncologists and researchers.
Assessment: The book is unique in its concept and content and cannot be easily compared with any available literature. There are some grammatical errors and inconsistencies, and the references are not organized in a user-friendly manner. However, this book, the product of painstaking efforts by a single author, cannot be ignored.

Doody's Review Service

"This book will be of value to those learning about malignant disease and wanting to gain insight into the patterns of spread of primary malignancies. In addition, the first part of the book is useful in reviewing the likely origins of metastatic disease in the various sites. It provides a wealth of information and references on the subject of metastatic disease and would be a useful addition to the library of any department dealing with the diagnosis, investigation and treatment of malignant disease."

(Mr P. Allan, Royal Infirmary, Edinburgh)

From the Publisher

Reviewer: Athanassios Argiris, MD(Northwestern University Feinberg School of Medicine)
Description: This eye-catching book deals exclusively with the metastatic spread of malignancy. Each organ that may harbor metastatic malignancy is examined; the author conducts a comprehensive review of all potential primary tumors that metastasize to a particular site (metastasis to). Anatomical and pathological background as well as the clinical presentation of patients with metastatic tumors is covered. In the second part of the book, a reverse analysis is conducted, and each primary tumor site is reviewed for its potential for metastases to various organs (metastatic from).
Purpose: The knowledge of metastatic patterns is fundamental to the practice and science of oncology. During his career the author has been intrigued by the metastatic potential of tumors. In this book, he focuses on the incident, symptoms, pathology, diagnosis, and imaging associated with metastatic sites. The goal is to make the clinician aware of all possibilities of metastasis and of the problems that are generated by it. Common as well as unexpected locations of metastatic spread are covered.
Audience: The audience for this book can be broad and can encompass any member of the multidisciplinary team involved in the management of cancer.
Features: Each chapter contains detailed enumeration of various studies, mainly case series, which have reported the incidence of metastases from or to various sites. The first part of the book concerns organs and sites where tumor cells metastasize, to answer the question, "Where is the primary organ?" when a metastatic focus is identified. Metastatic sites covered include the thoracic, abdominal, and head and neck organs as well as the nervous system, bones, lymph nodes, and others. The second part reviews the metastatic potential of each primary organ asking the question, "Where do tumors metastasize?" This book contains encyclopedic knowledge that maybe useful to clinical oncologists and researchers.
Assessment: The book is unique in its concept and content and cannot be easily compared with any available literature. There are some grammatical errors and inconsistencies, and the references are not organized in a user-friendly manner. However, this book, the product of painstaking efforts by a single author, cannot be ignored.