The Developing Human: Clinically Oriented Embryology / Edition 11

by Keith L. Moore BA, MSc, PhD, DSc, FIAC, FRSM, FAAA, T. V. N. Persaud MD, PhD, DSc, FRCPath (Lond.), Mark G. Torchia MSc, PhD

Overview

The 7th Edition of this classic book delivers more clinically oriented information on embryology and teratology than ever before. Week by week, stage by stage, you'll explore how organs and systems develop, why and when birth defects occur, and what the vital roles of the placenta and fetal membranes are in development.

Product Details

ISBN-13:	9780323611541
Publisher:	Elsevier Health Sciences
Publication date:	03/01/2019
Edition description:	New Edition
Pages:	522
Sales rank:	595,948
Product dimensions:	8.50(w) x 10.80(h) x 0.90(d)

About the Author

Moore, Keith L., PhD, FIAC, FRSM (Univ of Toronto); Persuad, T.V.N., MD, PhD, DSc, FRCPath (Lond) (Univ of Manitoba)

Table of Contents

1	Introduction to the Developing Human	1
	Developmental Periods	2
	Significance of Embryology	8
	Historical Gleanings	9
	Descriptive Terms in Embryology	12
	Clinically Oriented Problems	14
2	The Beginning of Human Development: First Week	15
	Gametogenesis	16
	Uterus, Uterine Tubes, and Ovaries	22
	Female Reproductive Cycles	25
	Transportation of Gametes	29
	Maturation of Sperms	31
	Viability of Gametes	31
	Fertilization	31
	Cleavage of Zygote	36
	Formation of Blastocyst	37
	Summary of First Week	39
	Clinically Oriented Problems	41
3	Formation of Bilaminar Embryonic Disc: Second Week	43
	Completion of Implantation and Continuation of Embryonic Development	44
	Development of Chorionic Sac	47
	Implantation Sites of Blastocyst	47
	Summary of Implantation	51
	Summary of Second Week	52
	Clinically Oriented Problems	53
4	Formation of Germ Layers and Early Tissue and Organ Differentiation: Third Week	59
	Gastrulation: Formation of Germ Layers	60
	Neurulation: Formation of Neural Tube	67
	Development of Somites	69
	Development of Intraembryonic Coelom	70
	Early Development of Cardiovascular System	70
	Further Development of Chorionic Villi	71
	Summary of Third Week	72
	Clinically Oriented Problems	75
5	Organogenetic Period: Fourth to Eighth Weeks	77
	Phases of Embryonic Development	78
	Folding of the Embryo	78
	Germ Layer Derivatives	80
	Control of Embryonic Development	80
	Highlights of Fourth to Eighth Weeks	84
	Estimation of Embryonic Age	94
	Summary of Fourth to Eighth Weeks	95
	Clinically Oriented Problems	98
6	The Fetal Period: Ninth Week to Birth	101
	Estimation of Fetal Age	103
	Highlights of Fetal Period	104
	Expected Date of Delivery	109
	Factors Influencing Fetal Growth	110
	Procedures for Assessing Fetal Status	113
	Summary of Fetal Period	116
	Clinically Oriented Problems	116
7	Placenta and Fetal Membranes	119
	Placenta	120
	Parturition (Childbirth)	131
	Amnion and Amniotic Fluid	138
	Yolk Sac	143
	Allantois	143
	Multiple Pregnancies	144
	Summary of Placenta and Fetal Membranes	150
	Clinically Oriented Problems	153
8	Human Birth Defects	197
	Classification of Birth Defects	158
	Teratology--Study of Abnormal Development	158
	Anomalies Caused by Genetic Factors	159
	Anomalies Caused by Environmental Factors	173
	Anomalies Caused by Multifactorial Inheritance	184
	Summary of Human Birth Defects	184
	Clinically Oriented Problems	185
9	Body Cavities, Mesenteries, and Diaphragm	187
	The Embryonic Body Cavity	188
	Development of the Diaphragm	192
	Congenital Diaphragmatic Hernia	195
	Summary of Development of Body Cavities	197
	Clinically Oriented Problems	199
10	The Pharyngeal Apparatus	201
	Pharyngeal Arches	202
	Pharyngeal Pouches	209
	Pharyngeal Grooves	212
	Pharyngeal Membranes	212
	Development of Thyroid Gland	215
	Development of Tongue	218
	Development of Salivary Glands	222
	Development of Face	222
	Development of Nasal Cavities	226
	Development of Palate	228
	Summary of Pharyngeal Apparatus	238
	Clinically Oriented Problems	239
11	The Respiratory System	241
	Development of Larynx	242
	Development of Trachea	242
	Development of Bronchi and Lungs	245
	Summary of Respiratory System	252
	Clinically Oriented Problems	252
12	The Digestive System	255
	Foregut	256
	Development of Spleen	266
	Midgut	266
	Hindgut	275
	Summary of Digestive System	282
	Clinically Oriented Problems	284
13	The Urogenital System	287
	Development of Urinary System	288
	Development of Suprarenal Glands	303
	Development of Genital System	304
	Development of Inguinal Canals	322
	Summary of Urogenital System	325
	Clinically Oriented Problems	326
14	The Cardiovascular System	329
	Early Development of Heart and Vessels	330
	Final Prenatal Development of Heart	336
	Anomalies of Heart and Great Vessels	347
	Aortic Arch Derivatives	357
	Aortic Arch Anomalies	360
	Fetal and Neonatal Circulation	364
	Development of Lymphatic System	371
	Summary of Cardiovascular System	377
	Clinically Oriented Problems	379
15	The Skeletal System	381
	Development of Bone and Cartilage	382
	Development of Joints	385
	Development of Axial Skeleton	386
	Development of Appendicular Skeleton	395
	Summary of Skeletal System	398
	Clinically Oriented Problems	398
16	The Muscular System	401
	Development of Skeletal Muscle	402
	Development of Smooth Muscle	404
	Development of Cardiac Muscle	404
	Summary of Muscular System	406
	Clinically Oriented Problems	406
17	The Limbs	409
	Early Stages of Limb Development	410
	Final Stages of Limb Development	410
	Cutaneous Innervation of Limbs	412
	Blood Supply to Limbs	412
	Anomalies of Limbs	414
	Summary of Limb Development	421
	Clinically Oriented Problems	423
18	The Nervous System	427
	Origin of Nervous System	428
	Development of Spinal Cord	428
	Congenital Anomalies of Spinal Cord	435
	Development of Brain	439
	Congenital Anomalies of Brain	451
	Development of Peripheral Nervous System	456
	Development of Autonomic Nervous System	461
	Summary of Nervous System	461
	Clinically Oriented Problems	462
19	The Eye and Ear	465
	Development of Eye and Related Structures	466
	Development of Ear	476
	Summary of Development of Eye	482
	Summary of Development of Ear	482
	Clinically Oriented Problems	482
20	The Integumentary System	485
	Development of Skin	486
	Development of Hair	488
	Development of Nails	491
	Development of Mammary Glands	492
	Development of Teeth	494
	Summary of Integumentary System	500
	Clinically Oriented Problems	500
	Discussion of Clinically Oriented Problems	503
	Appendices	515
	Timetable of Human Prenatal Development--1 to 6 weeks	514
	Timetable of Human Prenatal Development--7 to 38 weeks	516
	Critical Periods in Human Development	518
	Index	521

What People are Saying About This

From the Publisher

A clear, comprehensive and clinically oriented guide to human embryology.

Editorial Reviews

3 Stars from Doody

This is a clear and concise treatise on embryology with a special focus on clinically related topics. This sixth edition represents a considerable improvement over the fifth edition, published in 1993. Geared toward first or second-year medical students, the purpose is to enlighten the reader about the intricacies of embryological development as well as introduce the student to the molecular basis of development as it applies to clinically relevant issues. Although targeted toward novice medical students, practitioners in the field of obstetrics and gynecology would find this work a useful review and reference tool. Undergraduate students in biology, nursing, and other health related fields could also benefit from its use. The authors succeed in highlighting the key events of human development from gametogenesis to birth. They accomplish this journey through the use of simplistic, yet informative illustrations and unencumbered text. A sprinkling of scanning electron micrographs coupled with clinical correlations and study questions help to punctuate important facts and processes. Five beautifully illustrated timetables found in the appendix serve as ready reference to salient facts. This is, indeed, an easy-to-read account of human embryogenesis. The authors, by virtue of increasing the amount of clinical material, adding new color photography, including more scanning electron micrographs, expanding sections on teratology, and including simplified information on molecular mechanisms, have perhaps set a new standard for teaching embryology to first-year medical students. In a time when medical students are required to digest even more rote facts and are also thrown even earlierinto the clinical fray, this book should serve as a welcome addition to their educational war chest.

Michael F. Dauzvardis

Reviewer: Michael F. Dauzvardis, PhD (Loyola University Medical Center)
Description: This is a clear and concise treatise on embryology with a special focus on clinically related topics. This sixth edition represents a considerable improvement over the fifth edition, published in 1993.
Purpose: Geared toward first or second-year medical students, the purpose is to enlighten the reader about the intricacies of embryological development as well as introduce the student to the molecular basis of development as it applies to clinically relevant issues.
Audience: Although targeted toward novice medical students, practitioners in the field of obstetrics and gynecology would find this work a useful review and reference tool. Undergraduate students in biology, nursing, and other health related fields could also benefit from its use.
Features: The authors succeed in highlighting the key events of human development from gametogenesis to birth. They accomplish this journey through the use of simplistic, yet informative illustrations and unencumbered text. A sprinkling of scanning electron micrographs coupled with clinical correlations and study questions help to punctuate important facts and processes. Five beautifully illustrated timetables found in the appendix serve as ready reference to salient facts.
Assessment: This is, indeed, an easy-to-read account of human embryogenesis. The authors, by virtue of increasing the amount of clinical material, adding new color photography, including more scanning electron micrographs, expanding sections on teratology, and including simplified information on molecular mechanisms, have perhaps set a new standard for teaching embryology to first-year medical students. In a time when medical students are required to digest even more rote facts and are also thrown even earlier into the clinical fray, this book should serve as a welcome addition to their educational war chest.

Doody's Review Service

"...packed with excellent and colourful pictures of explaining how the various structures develop and change with time...Basically this is a good choice for someone who likes embryology and wants to get a good mark, not just a pass." Medical Student, University of Nottingham

From the Publisher