The Biology of Cancer / Edition 2

The Biology of Cancer / Edition 2

by Robert A. Weinberg
ISBN-10:
0815345291
ISBN-13:
9780815345299
Pub. Date:
07/29/2014
Publisher:
Norton, W. W. & Company, Inc.
The Biology of Cancer / Edition 2

The Biology of Cancer / Edition 2

by Robert A. Weinberg
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Overview

The Biology of Cancer is a new textbook for undergraduate and graduate biology students as well as medical students studying the molecular and cellular bases of cancer. The book presents the principles of cancer biology in an organized, cogent, and in-depth manner. The clarity of writing and the lucid full-color art program make the book accessible and engaging. The information unfolds through the presentation of key experiments, which give readers a sense of discovery, and provide insights into the conceptual foundation underlying modern cancer biology. A CD-ROM packaged with the book contains figures from the book, additional sidebars from the text, movies, and audio files of mini-lectures.

Besides its value as a textbook, The Biology of Cancer will be a useful reference for individuals working in biomedical laboratories and for clinicians.


Product Details

ISBN-13: 9780815345299
Publisher: Norton, W. W. & Company, Inc.
Publication date: 07/29/2014
Edition description: Second Edition
Pages: 960
Product dimensions: 8.20(w) x 10.80(h) x 1.10(d)

About the Author

Robert A. Weinberg is a founding member of the Whitehead Institute for Biomedical Research. He is the Daniel K. Ludwig Professor for Cancer Research and Professor in the Massachusetts Institute of Technology (MIT) Department of Biology. His research is focused on the molecular and cellular mechanisms of cancer pathogenesis. He was awarded the U.S. National Medal of Science in 1997.

Table of Contents

Preface
Chapter 1: The Biology and Genetics of Cells and Organisms
Chapter 2: The Nature of Cancer
Chapter 3: Tumor Viruses
Chapter 4: Cellular Oncogenes
Chapter 5: Growth Factors and Their Receptors
Chapter 6: Cytoplasmic Signaling Circuitry Programs Many of the Traits of Cancer
Chapter 7: Tumor Suppressor Genes
Chapter 8: pRb and Control of the Cell Cycle Clock
Chapter 9: p53 and Apoptosis: Master Guardian and Executioner
Chapter 10: Eternal Life: Cell Immortalization and Tumorigenesis
Chapter 11: Multistep Tumorigenesis
Chapter 12: Maintenance of Genomic Integrity and the Development ofCancer
Chapter 13: Dialogue Replaces Monologue: Heterotypic Interactions and the Biology of Angiogenesis
Chapter 14: Moving Out: Invasion and Metastasis
Chapter 15: Crowd Control: Tumor Immunology and Immunotherapy
Chapter 16: The Rational Treatment of Cancer
Glossary
Abbreviations/Acronyms

What People are Saying About This

From the Publisher

This is an impressively thoughtful, beautifully balanced analysis of where we stand today in the critical attempt to understand, and thereby defeat cancer as a scourge on humanity. Not only is it the perfect text for a serious course on cancer biology, it should be read by every cancer researcher - Bruce Alberts, University of California, San Francisco, USA

The Biology of Cancer is no doubt the definitive statement on its topic today. -Science, 11 August 2006: Vol. 313. no. 5788

There is no comparable text in cancer biology and no single book that is so current and informative. -Nature, November 30, 2006, Vol 444

'The Biology of Cancer, written by the distinguished American cancer biologist Robert Weinberg, is by far the most extensive of these new works and, as the product of a single author, is a remarkable achievement. The book is beautifully illustrated in full colour and well supplied with key review articles. It is extremely well written in language that should be accessible to the non-expert. Overall, this is a remarkable achievement that is by far the most comprehensive coverage of this field available.' - The Times Higher Education Supplement, February 23rd 2007

"The breadth of the topics covered, the clear writing style, the logical organization and the beautiful figures make The Biology of Cancer a classic text for any biologist interested in cancer...An additional strength of the book is the multimedia CD...¦Thus, The Biology of Cancer is not only a great read but also an outstanding learning tool."-Nature Cell Biology (November 2007) vol. 9, no. 11

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