Table of Contents
List of contributors vii
Preface xiii
Section 1 Introduction
1 Neurobiology and etiology of primary schizophrenia: current status Matcheri S. Keshavan Ripu D. Jindal 3
2 The concept of organicity and its application to schizophrenia Perminder S. Sachdev 16
3 Secondary hallucinations Mark Walterfang Ramon Mocellin David L. Copolov Dennis Velakoulis 21
Section 2 The neurology of schizophrenia
4 The neurologic examination in schizophrenia Richard D. Sanders Matcheri S. Keshavan 47
5 Functional neuroimaging in schizophrenia Serge A. Mitelman Jane Zhang Monte S. Buchsbaum 60
Section 3 Organic syndromes of schizophrenia
Epilepsy and schizophrenia
6 Schizophrenia-like psychosis and epilepsy Perminder S. Sachdev 79
7 Understanding the pathophysiology of schizophrenia through the looking glass of forced normalization Ennapadam S. Krishnamoorthy Seethalakshmi Ramanathan 103
Drugs and schizophrenia-like psychosis
8 Substance-induced psychosis: an overview Jagadisha Thirthalli Vivek Benegal Bangalore N. Gangadhar 112
9 Stimulants and psychosis Nash N. Boutros Matt P. Galloway Eric M. Pihlgren 127
10 Psychotomimetic effects of PCP, LSD, and Ecstasy: pharmacological models of schizophrenia? Vibeke S. Catts Stanley V Catts 141
11 Schizophrenia secondary to cannabis use Wayne Hall Louisa Degenhardt 169
12 Toxic psychosis Rajeev Kumar Jeffrey C. L. Looi 179
Other neurological disorders
13 Schizophrenia-like psychosis and traumatic brain injury Perminder S. Sachdev 186
14 Cerebrovascular disease and psychosis Osvaldo P. Almeida Sergio E. Starkstein 197
15 Neurodegenerative disorders (Alzheimer's Disease, fronto-temporal dementia) and schizophrenia-like psychosis Nicola T. Lautenschlager Alexander R Kurz 204
16 Storage disorders and psychosis Mark Walterfang Dennis Velakoulis 214
17 Mitochondrial disorders and psychosis Dennis Velakoulis and Mark Walterfang 229
18 Psychosis associated with leukodystrophies Patricia I. Rosebush Rebecca Anglin Michael Mazurek 241
19 Normal pressure hydrocephalus Julian Trollor 257
20 Brain tumors Malcolm Hopwood Lyn-May Lim 263
21 Demyelinating disease and psychosis Anthony Feinstein 273
Systemic disorders
22 Infection and schizophrenia Alan S. Brown Ezra S. Susser 279
Genetic disorders related to SLP
23 The status of genetic investigations of schizophrenia Bryan Mowry 288
24 Velocardiofacial syndrome (chromosome 22q11.2 deletion syndrome) as a model of schizophrenia Vandana Shashi Margaret N. Berry 309
25 Psychosis in Prader-Willi Syndrome Stewart L. Einfeld Sophie Kavanagh Arabella Smith Bruce J. Tonge 328
26 Friedreich's Ataxia and schizophrenia-like psychosis Perminder S. Sachdev 332
27 Wilson's Disease Edward C. Lauterbach Leslie Lester-Burns 337
28 Huntington's Disease and related disorders and their association with schizophrenia-like psychosis Perminder S. Sachdev 348
29 Fahr's Disease and psychosis Kim Burns Henry Brodaty 358
Section 4 Related concepts
30 The Charles Bonne tSyndrome William Burke 369
31 Acute brief psychosis-an organic syndrome? Anand K. Pandurangi 380
Section 5 Treatment
32 Drug treatment of secondary schizophrenia Michael D. Jibson Rajiv Tandon 393
33 Nonpharmacological interventions in secondary schizophrenia David J. Kavanagh Jennifer M. Connolly Kim T. Mueser 406
Index 419
