Table of Contents
List of Tables ix
List of Figures xi
Preface xiii
Acknowledgments xv
Chapter 1 Overview: Twenty Key Principles
Planning
Chapter 2 Laying the Groundwork 9
Chapter 3 The Methodology 15
Chapter 4 Minimizing Bias 29
Chapter 5 The Data Collection/Case Report Form 37
Chapter 6 Reproducible Eligibility Criteria 43
Chapter 7 Randomization, Blinding, and Confidentiality 47
Chapter 8 End Points and Outcome 53
Chapter 9 Sample Size and Power 59
Chapter 10 Preparing for Modern Statistical Analysis 65
Chapter 11 Avoiding Common Criticisms 69
Chapter 12 Preparing to Write a Publishable Paper 77
Observing
Chapter 13 Collecting Data and Handling Missing Data 91
Chapter 14 Analyzing Data: Statistical Analysis for Reproducible Research 95
Chapter 15 Interpreting the Data 103
Chapter 16 Univariate Analysis 109
Chapter 17 Nonparametric Tests 119
Chapter 18 Matching and Propensity Score Analysis 121
Chapter 19 Multivariate Analysis and Model Validation 123
Writing
Chapter 20 Title Page 133
Chapter 21 Abstract 137
Chapter 22 Introduction 139
Chapter 23 Methods 145
Chapter 24 Results 163
Chapter 25 Discussion 189
Chapter 26 References 199
Chapter 27 Industry Publications 203
Editing
Chapter 28 Preparing Your Manuscript for Submission 207
Chapter 29 Small but Significant Points to Consider 217
Chapter 30 Improving Your Writing 219
Chapter 31 Fixes for Problematic Terms 231
Revising
Chapter 32 Revising the Final Draft 237
Chapter 33 The Cover Letter 241
Chapter 34 Responding to Peer Reviewers' Comments 245
Appendixes
A Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical journals (ICMJE Recommendations) (formerly known as the Uniform Requirements for Manuscripts Submitted to Biomedical Journals) 251
B Peer Review Questionnaires from First Edition and Second Edition 275
C Sample Data Collection Form 293
D World Medical Association Declaration of Helsinki 299
Ode to Multiauthorship: A Multicentre, Prospective Random Poem 305
Bibliography 307
Index 313
