Oxidants, Antioxidants And Free Radicals / Edition 1

by Steven Baskin, Harry Salem

Overview

This volume collates articles investigating antioxidant, oxidant and free radical research. It examines the role of such research in health and disease, particulary with respect to developing greater understanding about the many interactions between oxidants and antioxidants, and how such substances may act as natural protectants and /or natural toxicants.

Product Details

ISBN-13:	9781560326441
Publisher:	Taylor & Francis
Publication date:	11/12/1997
Edition description:	New Edition
Pages:	388
Product dimensions:	6.12(w) x 9.19(h) x (d)

About the Author

Baskin, Steven; Salem, Harry

Table of Contents

Redox, radicals and antioxidants; analysis of free radicals; their products and antioxidants; vitamin E - vitamin E and polyunsturated fats; antioxidants and pro-oxidant relationship; alpha-tocopheral, beta- Carotene and oxidative modification of human, low-density lipoprotein; response of antioxidant system to physical and chemical stress; zinc as a cardioprotective antioxidant; ascorbic acid, melatonin and the adrenal gland - a commentary; antioxidant properties of Glutathione and its role in tissue protection; antioxidant effects of hypotaurine and taurine; antioxidative activity of ergothionine and ovothiol; the toxicology of antioxidants; toxicity of oxygen and ozone; peroxidation of lipids and liver damage; role of free radicals in alcohol-induced tissue injury; oxidant injury from inhaled particle matter; edmagenic gases cause lung toxicity by generating reactive intermediates species RIS; lipid peroxidation and antioxidant depletion induced by blast overpressure; food antioxidants - their dual role in carcinogenesis; anticarcinogenic effects of synthetic phenolic antioxidants.

Editorial Reviews

Reviewer: Frederick E. Samson, DO, PhD (University of Kansas Medical Center)
Description: A variety of topics are covered in this book, including definitions of the basic terms and language of oxygen/nitrogen free radical research, tables of standard free energies of relevant reactions, chemical structures, and analytical methods. Some chapters are overviews, some are reports of research, and some deal with unusual topics. The topics are representative of the field, authoritative, well written, and current. Some topics such as reactive oxygen species in cell signaling and redox regulation of gene expression are not included and would have been valuable.
Purpose: It is designed to help researchers and educators stay abreast of developments in this rapidly growing area of investigation and to provide a source of reference material for use in research and in graduate teaching. It is intended to stimulate cross-fertilization of ideas and give the reader insights into trends and future implications. Most of these objectives are achieved in a manageably sized book
Audience: Scientists and graduate and post-graduate follows in environmental sciences, nutrition, pathology, pharmacology, and toxicology will find this book useful. Also, academic clinicians will find this book useful because the overproduction of oxygen/nitrogen reactive species is linked to a large number of diseases and traumas. The chapters are written by credible, respected authorities.
Features: The illustrations are diagrams, chemical structures, schematics, and graphic plots and are pertinent and informative. The text is well referenced, current, and complete with all coauthors and titles. Unfortunately there are a number of misspelled names in some references. The index is complete and useful. The type size is very small, a shade less than 9 points and might be uncomfortable for some readers. However, with such small type and narrow margins, a large amount of information is packed into a handy sized book.
Assessment: It is high quality and useful for graduate students, scientists in biomedical research, and academic medical clinicians. The subject matter is written by experts and is clearly presented. There is a valuable mix of tutorials, reviews, and experimental reports. I recommend that university and medical school libraries buy this book. Individuals directly involved in or contemplating doing research in this field will find this book a helpful source of information.

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