Osteoporosis in Clinical Practice: A Practical Guide for Diagnosis and Treatment / Edition 2

by Piet Geusens, Philip N. Sambrook, Robert Lindsay

Overview

When I was a young intern in internal medicine,osteoporosis was defined mainly as a fracture occurring in elderly people. However,although plain X-ray examination was recognized as an insensitive way to detect osteoporosis, hypodense bone was already considered as the reflection of the disease. Over the past 20 years, con­ siderable progress has been accomplished. In terms of prevalence, incidence, risk factors, and the burden of osteoporosis and low-energy fracture, we can appreciate the magnitude of the problem and its impact on quality oflife. Weare wellaware that vertebral fracture, which can be acutely associated with a low clinical expression, leads to significant long-term impairments. The costs for the individual and for the health budget, Le. society,are estimated better. Wenow have a clear definition of the disease, such as low bone mass and architectural defects, resulting in increased fragility. For the former part of the definition, the clinician can use accurate and pre­ cise tools allowing them to distinguish how their patient's bone mineral content differs from that of a young healthy population in which fracture occurs very rarely. For the second series of fragility determinants, i. e. structure, methods are in rapid progress and will provide information to clinicians on these variables in the near future. Basicand clinical research have allowed major improvements in the understanding of the pathophysiology of the disease. Newgenes implicated in lowand/or high bone mass have been characterized.

Product Details

ISBN-13:	9781852337575
Publisher:	Springer London
Publication date:	04/27/2004
Edition description:	2nd ed. 2004
Pages:	224
Product dimensions:	6.10(w) x 9.25(h) x 0.02(d)

Table of Contents

I General aspects of bone, osteoporosis and fractures.- 1 Normal Skeletal Structure and Function.- 2 Physiology of Calcium Homeostasis and Bone Remodeling.- 3 Biomechanics of Bone and Fracture.- 4 Pathophysiology of Fractures.- 5 Epidemiology of Osteoporotic Fractures.- 6 Socioeconomic Impact.- 2 Investigations in Osteoporosis.- 7 Bone Densitometry, Radiography, and Quantitative Ultrasound for the Diagnostic Assessment of Osteoporosis.- 8 Biochemical Indices of Bone Turnover.- 9 Dual-energy X-ray-based Absorptiometry in Daily Clinical Practice.- 10 Differential Diagnos is: Back Pain and Osteoporosis.- 11 Differential Diagnosis: Bone Pain and Fractures.- 12 Falls in Older People.- 13 Genes and Osteoporosis.- 3 Treatment of Postmenopausal Osteoporosis.- 14 Prevention Early After Menopause.- 15 Pharmacologic and Non-pharmacologic Strategies to Prevent Hip Fracture in Old Age.- 16 Selective Estrogen Receptor Modulators.- 17 Bisphosphonate Therapy for Postmenopausal Osteoporosis.- 18 Anabolic Drug Therapy in Osteoporosis.- 19 Surgical Therapy of Fractures.- 4 Other Aspects of Osteoporosis.- 20 Osteoporosis in Men.- 21 Corticosteroid Osteoporosis.- 22 Tumor Bone Diseases.- 23 Immobilization, Exercise, and Osteoporosis.- 24 Nutrition and Osteoporosis.- 25 The Menopause: A Woman’s View.- 5 The Future of Diagnosis and Treatment of Osteoporosis.- 26 Future Developments: Risk Assessment.- 27 Future Therapies.- 28 How to Interpret New Data.

Editorial Reviews

Reviewer: Edward Abraham, MD (University of Illinois at Chicago College of Medicine)
Description: This softcover book deals with the diagnosis and treatment of patients with decreased bone mass or osteoporosis.
Purpose: The purpose is to help physicians in clinical practice better identify patients with osteoporosis and select the best treatment strategy for the disorder. These objectives are fully met.
Audience: The book is written mainly for physicians in any specialties caring for patients with osteoporosis. The editors are fully qualified.
Features: The book presents the clinical practitioner with well thought out questions and answers to many important issues. The book is divided into five parts covering general aspects of bone, osteoporosis and fractures; investigations in osteoporosis; treatment of postmenopausal osteoporosis; other aspects of osteoporosis; and the future of diagnosis and treatment of osteoporosis. There are several useful tables and figures. Radiographic appearance of osteoporotic bones and fractures are not used in this work. The authors do not cite references in the body of the text but instead provide recommended further readings at the end of each chapter.
Assessment: Osteoporosis is an important and growing concern in the older population. It is associated with bone pain and fractures which can be life threatening. Any patient over the age of 50 with a bone fracture is recommended to have an osteoporosis workup and treatment if necessary. This book is highly recommended for all clinicians caring for patients with osteoporosis. Medical students are encouraged to read this work. It serves as an excellent reference.

Doody's Review Service

From the reviews of the second edition:

"The authors have gathered a number of specialists in the field of osteoporosis to give us a general review of the latest clinical knowledge. … This book is of great value for every clinician dealing with osteoporosis in adults." (N. Allington, Acta Orthopædica Belgica, Vol. 71 (2), 2005)

"During the last 20 years, considerable progress has been made in the knowledge of osteoporosis in diagnosis as well as in treatment, be it preventive or curative. P. Geusens, P. N. Sambrook and R. Lindsay offer us a comprehensive analysis of the subject in their second edition of Osteoporosis in Clinical Practice." (L. Balabaud, European Journal of Orthopaedic Surgery & Traumatology, Vol. 16, 2006)

From the Publisher

Reviewer: Edward Abraham, MD(University of Illinois at Chicago College of Medicine)
Description: This softcover book deals with the diagnosis and treatment of patients with decreased bone mass or osteoporosis.
Purpose: The purpose is to help physicians in clinical practice better identify patients with osteoporosis and select the best treatment strategy for the disorder. These objectives are fully met.
Audience: The book is written mainly for physicians in any specialties caring for patients with osteoporosis. The editors are fully qualified.
Features: The book presents the clinical practitioner with well thought out questions and answers to many important issues. The book is divided into five parts covering general aspects of bone, osteoporosis and fractures; investigations in osteoporosis; treatment of postmenopausal osteoporosis; other aspects of osteoporosis; and the future of diagnosis and treatment of osteoporosis. There are several useful tables and figures. Radiographic appearance of osteoporotic bones and fractures are not used in this work. The authors do not cite references in the body of the text but instead provide recommended further readings at the end of each chapter.
Assessment: Osteoporosis is an important and growing concern in the older population. It is associated with bone pain and fractures which can be life threatening. Any patient over the age of 50 with a bone fracture is recommended to have an osteoporosis workup and treatment if necessary. This book is highly recommended for all clinicians caring for patients with osteoporosis. Medical students are encouraged to read this work. It serves as an excellent reference.