One-Locus and Multi-Locus Theory and Recombination / Edition 1

by Igor M. Rouzine

Overview

The book will benefit a reader with a background in physical sciences and applied mathematics interested in the mathematical models of genetic evolution. In the first chapter, we analyze several thought experiments based on a basic model of stochastic evolution of a single genomic site in the presence of the factors of random mutation, directional natural selection, and random genetic drift. In the second chapter, we present a more advanced theory for a large number of linked loci. In the third chapter, we include the effect of genetic recombination into account and find out the advantage of sexual reproduction for adaptation. These models are useful for the evolution of a broad range of asexual and sexual populations, including virus evolution in a host and a host population.

Product Details

ISBN-13:	9783110607895
Publisher:	De Gruyter
Publication date:	11/23/2020
Series:	De Gruyter Series in Mathematics and Life Sciences , #8
Pages:	181
Product dimensions:	6.69(w) x 9.45(h) x (d)
Age Range:	18 Years

About the Author

Igor M. Rouzine, Russian Academy of Sciences, Russian Federation.