Nitric Oxide Donors: Novel Biomedical Applications and Perspectives

by Amedea Seabra

Overview

Nitric Oxide Donors: Biomedical Applications and Perspectives presents the current state of art, challenges and innovations in the design of therapeutics nitric oxide donors with great impact in several aspects of human physiology and pathophysiology. Although considerable innovative progress has been achieved using Nitric Oxide donors in biomedical applications, certain drawbacks still need to be overcome to successfully translate these research innovations into clinical applications.

This book encompasses several topics on nitric oxide such as its sources and biological properties; its performance in the cardiovascular and neurologic systems, in the human skin and its application in the treatment of neglected diseases, neurodegenerative disorders, and cancer. Additionally, it covers its role in inflammation and immunity, penile erection function, photodynamic therapy, antimicrobial activities. It also discusses the future of nitric oxide donors in combination with other therapeutic drugs, in implantable sensors, and nitric oxide releasing hydrogels and medical devices for topical applications.

The book is a valuable source for researchers on different areas of biomedical field who are interested in the improvements that these molecules can make in the treatment of several conditions.

Product Details

ISBN-13:	9780128092750
Publisher:	Elsevier Science
Publication date:	03/23/2017
Pages:	364
Product dimensions:	7.50(w) x 9.25(h) x (d)

About the Author

Amedea B. Seabra holds a diploma degree in Chemistry from University of São Paulo (USP). She finished her Ph.D. at Chemistry Institute, State University of Campinas (UNICAMP) in 2006. Thereafter, she worked as a Research Fellow at UNICAMP (2006–2008), and she took postdoctoral studies at the Chemistry and Biochemistry Department, Concordia University in Montreal, Canada (2008–2010).She is associated professor at Federal University of ABC (UFABC). Her present research is focused on the preparation, characterization and evaluation of the cytotoxicity of nitric oxide-releasing nanomaterials for biomedical and agricultural applications.

Table of Contents

1. Nitric Oxide Derivative Ruthenium Compounds as NO-Based Chemotherapeutic and Phototherapeutic Agents2. Nitric Oxide Donors for Treating Neglected Diseases3. Nitric Oxide-Donating Devices for Topical Applications4. Nitric Oxide Donors and Therapeutic Applications in Cancer5. Nitric Oxide Donors and Penile Erectile Function6. Nitric Oxide Donors in Nerve Regeneration7. Nitric Oxide Donors as Antimicrobial Agents8. Improving the Performance of Implantable Sensors with Nitric Oxide Release9. Strategies to Deliver Nitric Oxide Donors to Control Biofilms of Clinical and Industrial Interest10. Developing New Organic Nitrates for Treating Hypertension11. Nitric Oxide Donors in Brain Inflammation12. Synergistic Activities of Nitric Oxide and Various Drugs13. Hydrogels for Topical Nitric Oxide Delivery

What People are Saying About This

From the Publisher

This book provides a cutting edge overview of innovative uses for nitric oxide donors in the biomedical field, including challenges