Neuroleptic-induced Movement Disorders: A Comprehensive Survey

by Ramzy Yassa MD, N. P. V. Nair MD, Dilip V. Jeste MD

Overview

Although generally beneficial, neuroleptics often cause adverse effects, of which movement disorders are the most serious in terms of frequency and persistence. This book was prepared with the aim of improving understanding and clinical management of these treatment-caused conditions. The authors address the historical, clinical and neurobiological aspects of the most serious of these conditions, tardive dyskinesia, as well as related movement disorders such as parkinsonism, dystonia and akathisia. The authors also devote sections of the text to the measurement of tardive dyskinesia, geographical and ethnic variables, and management with novel neuroleptic agents and biofeedback.

Product Details

ISBN-13:	9780521033527
Publisher:	Cambridge University Press
Publication date:	02/01/2007
Edition description:	New Edition
Pages:	516
Product dimensions:	5.98(w) x 8.98(h) x 1.22(d)

About the Author

Yassa, Ramzy, MD (Douglas Hospital, Quebec); Nair, N. P. V., MD (Douglas Hospital, Quebec); Jeste, Dilip V., MD (UCSD)

The contributors represent the specialties of psychiatry, neurology, psychology, and neuroscience. Most are from universities and research institutes in the U.S., the U.K., Ireland, Germany, Denmark, Japan, Morocco, and Canada. Institutions prominently represented include Albert Einstein Coll of Medicine, St John of God Psychiatric Service in Dublin, Hiroshima Univ, and Nathan S Kline Institute for Psychiatric Research.

Table of Contents

Contributors; Preface; Part I. Historical Perspective: 1. Neuroleptic-induced movement disorders: historical perspective Marc-Alain Wolf, Ramzy Yassa and Pierre-Michel Llorca; Part II. Clinical Aspects of Tardive Dyskinesia: 2. Aging and tardive dyskinesia Bruce L. Saltz, John M. Kane, Margaret G. Woerner, Jeffrey A. Lieberman and José Ma. J. Alvir; 3. Gender as a factor in the development of tardive dyskinesia Ramzy Yassa and Dilip V. Jeste; 4. The Yale tardive dyskinesia study: a prospective incidence study among long-term outpatients William M. Glazer, Hal Morgenstern, Donna Raye Wagner and John Doucette; 5. Vulnerability to tardive dyskinesia in schizophrenia: an exploration of individual patient factors John L. Waddington, Eadbhard O'Callaghan, Peter Buckely, Cathy Madigan, Conall Larkin and Anthony Kinsella; 6. Tardive dyskinesia and affective disorder George Gardos and Jonathan O. Cole; 7. Diabetes mellitus and tardive dyskinesia Sukdeb Mukherjee and Sahebarao P. Mahadik; 8. Other factors in the development of tardive dyskinesia Ramzy Yassa; 9. Neuroleptic treatment and tardive dyskinesia George Gardos and Jonathan O. Cole; 10. Anticholinergic drugs as factors in the development of tardive dyskinesia Ramzy Yassa and N. P. V. Nair; Part III. Mechanisms Underlying Tardive Dyskinesia: 11. Neurochemistry of the basal ganglia N. P. V. Nair and T. E. G. West; 12. A reanalysis of the dopamine theory of tardive dyskinesia: the hypothesis of dopamine D1/D2 imbalance Linda Peacock and Jes Gerlach; 13. Tardive dyskinesia and phenylalanine metabolism: risk-factor studies Mary Ann Richardson, Cheryl Flynn, Laura Read, Margaret Reilly and Raymond Suckow; 14. Neuroendocrinological studies of tardive dyskinesia Margot Albus; 15. Cognitive deficits and tardive dyskinesia Marion E. Wolf, Alan S. DeWolfe and Aron D. Mosnaim; 16. Studies of tardive dyskinesia using computed tomography and magnetic-resonance imaging Christian L. Shriqui; 17. Rodent and other animal models of tardive dyskinesia during long-term neuroleptic-drug administration: controversies and implications for the clinical syndrome John L. Waddington; Part IV. Measurement of Tardive Dyskinesia: 18. Instrument measurements of tardive dyskinesia Michael P. Caligiuri; Part V. Tardive Dyskinesia in Different Populations: 19. Cultural aspects of tardive dyskinesia in Asia Shigeto Yamawaki, Teruo Hayashi; Ikuo Nagaoka, Hiroshi Saitoh, Norio Yokota and Yosuke Uchitomi; 20. Tardive dyskinesia in North America and the Middle East Driss Moussaoui; 21. Tardive dyskinesia in Europe H. A. McClelland and T. A. Kerr; 22. Role of ethnicity in the development of tardive dyskinesia Jonathan P. Lacro and Dilip V. Jeste; 23. Tardive dyskinesia in children and adolescents Mark Magulac and Dilip V. Jeste; Part VI. Other Neuropleptic-Induced Movement Disorders: 24. Drug-induced parkinsonism Thomas E. Hansen and William F. Hoffman; 25. Clinical aspects of neuroleptic-induced dystonia George A. Keepers and Linda Ganzini; 26. Tardive dystonia Paul Greene; 27. Tardive akathisia Robert E. Burke; Part VII. Treatment of Tardive Dyskinesia: 28. Development of novel antipsychotic drugs with reduced extrapyramidal side effects Allan Z. Safferman, Jeffrey A. Lieberman, Bruce J. Kinon, Daniel Umbricht, Jeffrey S. Aronowitz and John M. Kane; 29. GABAergic treatments for tardive dyskinesia Shawn L. Cassady, Gunvant K. Thaker and Carol A. Tamminga; 30. Using biofeedback to train suppression of the oral-lingual movements of tardive dyskinesia Ronald C. Fudge and Cecile E. Sison; Index.

Editorial Reviews

"This is an excellent new book...Written and edited by internationally recognized experts in the field, this book is a valuable contribution to psychiatry...Any clinician who is involved in the treatment of patients with chronic psychoses should read and refer to this book." Michael J. Schrift, Doody's Health Sciences Book Review Journal

"The book enhances our understanding of TD's neurobiological basis, and thus, it might help us to find new antipsychotics with anti-dyskinetic properties and other treatment strategies that could be used in the management of TD....this text is a comprhensive reference for researchers, psychiatrists and neurologists. It would be a useful addition to departmental and academic libraries." R. Ramasubbu, MD, FRCPC, Annals RCPSC

"This will be helpful for residents, fellows, practicing psychiatrists, researchers, and clinical neurologists with interest in Movement Disorders....the authors should be congratulated for completing the great task of writing this book..." S. Das, The Canadian Journal of Neurological Sciences

From the Publisher

3 Stars from Doody

This is an excellent new book covering the varieties of movement disorders induced by exposure to antipsychotic medications. Written and edited by internationally recognized experts in the field, this book is a valuable contribution to psychiatry. The purpose of the book is to improve clinicians understanding and clinical management of neuroleptic-induced movement disorders. The editors believe that we need to ""study these iatrogenic conditions in depth so as to understand them better and improve the management of our patients."" This book is a step toward that purpose. The intended audience is those interested in understanding the clinical uses of neuroleptic agents and the research into their adverse side effects. The book features 494 pages divided into seven parts and 30 chapters. Topics covered include an historical perspective, clinical aspects of tardive dyskinesia, mechanisms underlying tardive dyskinesia, measurement of tardive dyskinesia, cross cultural aspects of tardive dyskinesia, drug induced parkinsonism and dystonia, and treatment of tardive dyskinesia. There is an up-to-date reference section and useful index at the back of the book. This is a valuable new book on drug-induced movement disorders. Any clinician who is involved in the treatment of patients with chronic psychoses should read and refer to this book.

Michael J. Schrift

Reviewer: Michael Schrift, DO (University of Washington School of Medicine)
Description: This is an excellent new book covering the varieties of movement disorders induced by exposure to antipsychotic medications. Written and edited by internationally recognized experts in the field, this book is a valuable contribution to psychiatry.
Purpose: The purpose of the book is to improve clinicians understanding and clinical management of neuroleptic-induced movement disorders. The editors believe that we need to "study these iatrogenic conditions in depth so as to understand them better and improve the management of our patients." This book is a step toward that purpose.
Audience: The intended audience is those interested in understanding the clinical uses of neuroleptic agents and the research into their adverse side effects.
Features: The book features 494 pages divided into seven parts and 30 chapters. Topics covered include an historical perspective, clinical aspects of tardive dyskinesia, mechanisms underlying tardive dyskinesia, measurement of tardive dyskinesia, cross cultural aspects of tardive dyskinesia, drug induced parkinsonism and dystonia, and treatment of tardive dyskinesia. There is an up-to-date reference section and useful index at the back of the book.
Assessment: This is a valuable new book on drug-induced movement disorders. Any clinician who is involved in the treatment of patients with chronic psychoses should read and refer to this book.

Doody's Review Service