Neurochemical Correlates of Cerebral Ischemia / Edition 1

by Nicolas G. Bazan, Pierre Braquet, Myron D. Ginsberg

Overview

In this timely volume, eminent researchers provide detailed coverage of the relevant function of neurochemical correlates to cerebral ischemia as well as their pathophysiological significance.

Product Details

ISBN-13:	9780306439445
Publisher:	Springer-Verlag New York, LLC
Publication date:	01/28/1992
Series:	Advances in Neurochemistry Series , #7
Edition description:	New Edition
Pages:	392
Product dimensions:	6.00(w) x 9.00(h) x 1.00(d)

Table of Contents

1 Introduction: Current Biochemical and Molecular Approaches to the Study of Cerebral Ischemia.- 2 Metabolic Correlates of Focal Ischemia.- 3 Role of Pyruvate Dehydrogenase in Ischemic Injury.- 4 Disturbances of Protein and Polyamine Metabolism after Reversible Cerebral Ischemia.- 5 Oxygen Dependence of Neuronal Metabolism.- 6 Dysmetabolism in Lipid Brain Ischemia.- 7 Involvement of Calcium, Lipolytic Enzymes, and free Fatty acids in Ischemic Brain Trauma.- 8 Arachidonic Acid Lipoxygenase Products Participate in the Pathogenesis of Delayed Cerebral Ischemia.- 9 Biochemical Changes and Secondary Tissue Injury after Brain and Spinal Cord Ischemia!Reperfusion.- 10 Free Fatty Acid Liberation in the Pathogenesis and Therapy of Ischemic Brain Damage.- 11 Cerebral Ischemia and Polyphosphoinositide Metabolism.- 12 Protection Against Ischemic Brain Damage by Excitatory Amino Acid Antagonists.- 13 Acute Alterations in Phosphoinosttide Turnover.- 14 New Insights into the Role of Oxygen Radicals in Cerebral Ischemia.- 15 Biochemical Factors and Mechanisms of Secondary Brain Damage in Cerebral Ischemia and Trauma.- 16 Modulators of Neural Cell Signaling and Triggering of Gene Expression Following Cerebral Ischemia.- 17 Cellular and Metabolic Significance of Cellular Acid-Base Shifts in Human Stroke.

Editorial Reviews

Summarizes the current knowledge on neurochemical correlates of what most of us know as stroke, emphasizing their relevance to function and their pathophysiological significance. Provides a strong foundation for defining mechanisms, identifying possible therapeutic agents, and assessing new drugs. The 17 individually authored chapters sometimes overlap in their discussions of such topics as oxygen radicals, protein and polyamine metabolism, and biologically active lipids. Annotation c. Book News, Inc., Portland, OR (booknews.com)

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