Molecular Basis of Neuropsychiatric Disorders: from Bench to Bedside

by Shafiqur Rahman

Overview

Progress in Molecular Biology and Translational Science, Volume 167, provides the most topical, informative and exciting monographs available on a wide variety of research topics related to Models and Biological Targets in Drug Discovery for Attention Deficit Hyperactivity Disorder, Novel Targets for Parkinson-Depression Co-morbidity. Utility of Cannabidiol (CBD) in Neuropsychiatric Disorders: A Short Review of the Recent Pre-clinical and Clinical Findings, The Many Sides of Microglia in Alcohol Use Disorders, Stress, Anxiety, Molecular Targets and More, Calcineurin Signaling in Psychiatric Disorders, Emerging Evidence for the Role of Pituitary Adenylate Cyclase- Activating Peptide (PACAP) in Neuropsychiatric Disorders, and more.

Product Details

ISBN-13:	9780128188552
Publisher:	Elsevier Science
Publication date:	10/05/2019
Series:	Progress in Molecular Biology and Translational Science , #167
Pages:	266
Product dimensions:	6.00(w) x 9.00(h) x (d)

About the Author

Shafiqur Rahman, Ph.D. is Professor of Pharmacology in the Department of Pharmaceutical Sciences at South Dakota State University (SDSU) in Brookings, USA. He received his Ph.D. in Neuropharmacology from the Memorial University of Newfoundland, Canada. Dr. Rahman completed his post-doctoral fellowship in the Department of Psychiatry from Indiana University School of Medicine in Indianapolis in USA. Prior to joining SDSU, he worked as research scientist and faculty at the University of Kentucky in Lexington, USA and the University of Toronto, Canada.

Dr. Rahman's research focus is drug discovery in neuropharmacology, i.e. the development of novel therapeutic candidates for the treatment of alcohol/nicotine addiction and neuropsychiatric disorders using animal models. His research resulted in over 200 publications/presentations, including peer-reviewed scientific articles, reviews, book chapters, meeting abstracts and seminar presentations. Dr. Rahman served on numerous scientific review panels and editorial boards of several scientific Journals. He has authored or edited multiple books or Journals in drug addiction and neuropharmacology field. Dr. Rahman is also affiliated with a number of professional organizations, including Society for Neuroscience and American Society for Pharmacology and Experimental Therapeutics.

Table of Contents

1. Novel targets for parkinsonism-depression comorbidity Yousef Tizabi, Bruk Getachew, Antonei B. Csoka, Kebreten F. Manaye and Robert L. Copeland 2. Effects of cannabidiol (CBD) in neuropsychiatric disorders: A review of pre-clinical and clinical findings Sonja Elsaid, Stefan Kloiber and Bernard Le Foll 3. Stress, psychiatric disorders, molecular targets, and more Fatin Atrooz, Hesong Liu and Samina Salim 4. Calpain in the cleavage of alpha-synuclein and the pathogenesis of Parkinson's disease Ramsha Shams, Naren L. Banik and Azizul Haque 5. Calcineurin signaling as a target for the treatment of alcohol abuse and neuroinflammatory disorders Patrick J. Ronan, Sarah A. Flynn and Thomas P. Beresford 6. Emerging evidence for the role of pituitary adenylate cyclase-activating peptide in neuropsychiatric disorders Kabirullah Lutfy and Shankar Gollapudi 7. Glial mechanisms underlying major depressive disorder: Potential therapeutic opportunities Shafiqur Rahman and Sami Alzarea 8. Its complicated: The relationship between alcohol and microglia in the search for novel pharmacotherapeutic targets for alcohol use disorders Jennifer K. Melbourne, K. Ryan Thompson, Hui Peng and Kimberly Nixon 9. Microglia as possible therapeutic targets for autism spectrum disorders Megumi Andoh, Yuji Ikegaya and Ryuta Koyama

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From the Publisher

Contains cutting-edge reviews in molecular biology