Hematopathology in Oncology / Edition 1

by William G. Finn, LoAnn C. Peterson

Overview

Hematologist/oncologists rely heavily upon the discipline of hematopathology for the care and management of their patients. Whether interpreting a lymph node or bone marrow biopsy, directing a high throughput automated hematology laboratory, or translating testing modalities from the research bench to the clinical laboratory, hematopathologists and other laboratory medicine specialists provide a steady stream of critical data for the clinical practitioner. Recently the rapid advances in diagnosis and treatment of hematological disorders including the need to evaluate patients' eligibility for and monitor responses to rapidly evolving targeted therapies have made the close collaboration between pathologists and clinician practitioners even more essential. Our goal is to provide outstanding reviews of selected topics in hematopathology in a format that provides both general and historical background, as well as an overview of the state-of-the-art in diagnostic hematopathology, with an eye on future potential and future developments.

Product Details

ISBN-13:	9781402079191
Publisher:	Springer US
Publication date:	05/31/2004
Series:	Cancer Treatment and Research , #121
Edition description:	2004
Pages:	298
Product dimensions:	6.30(w) x 9.20(h) x 0.90(d)

Table of Contents

mRNA Microarray Analysis in Lymphoma and Leukemia.- Myelodysplastic/Myeloproliferative Diseases.- Relevance of Pathologic Classifications and Diagnosis of Acute Myeloid Leukemia to Clinical Trials and Clinical Practice.- Molecular Cytogenetic Studies for Hematological Malignancies.- The Plasma Cell Dyscrasias.- Advances in the Diagnosis and Classification of Chronic Lymphoproliferative Disorders.- Laboratory Hematology Practice.- Role of Fine Needle Aspiration in Lymphoma.- Angiogenesis in Leukemia and Lymphoma.- Clinical Flow Cytometry.- Hodgkin Lymphoma.

Editorial Reviews

Reviewer: Valerie L Ng, PhD MD(Alameda County Medical Center/Highland Hospital)
Description: This book consists of state-of-the-art chapters on selected topics in hematopathology/hematology as relates to oncology.
Purpose: The purpose of this book is to present selected topics in this area, including current diagnostic and treatment modalities in this rapidly evolving field. The authors have succeeded admirably in achieving their goal.
Audience: This book would appeal greatly to practicing hematopathologists, laboratory hematologists, clinical hematologists and oncologists, and all individuals in related subspecialty training programs (i.e., internal medicine subspecialties of hematology/oncology, laboratory medicine/pathology subspecialties of hematology or hematopathology).
Features: The 11 chapters cover (in keeping with the title) only selected topics. Although this book is by no means a comprehensive text of all hematopathology/hematology, it certainly covers each topic in depth and comprehensively. The first chapter on gene expression analysis in leukemias and lymphomas is very helpful to bring the reader up to speed on the latest technological applications (e.g., microarrays) and the clinical significance of the findings. Subsequent chapters focus on a single topic, and nicely blend and contrast historical information with current concepts of the particular disease. The chapter on myeloproliferative/myelodysplastic syndromes has an excellent discussion on chronic myelomonocytic leukemia (CMML), with emphasis on the key features distinguishing the myeloproliferative form from the myelodysplastic form. The chapter on plasma cell dyscrasias is probably one of the best I've seen; there is no question that it presents a state-of-the-art discussion of this group of baffling disorders. Finally, I was quite impressed to read about total laboratory automation in the laboratory hematology chapter and the excellent discourse on why such automation hasn't made more headway in clinical hematology laboratories. In short, this book has a seamless blend of laboratory and clinical information - a quintessential laboratory medicine type of book. My only general disappointment was the lack of high quality color photomicrographs of the various disease states. Black-and-white photomicrographs illustrate the concepts adequately, but color would have made this book completely irresistible.
Assessment: This is an excellent addition to the library of any practicing clinical or laboratory hematologist, hematopathologist, or oncologist.

Doody's Review Service

"The field of Hematopathology has witnessed remarkable advances over the last decade. Knowledge of the molecular and biologic alterations in hematologic malignancies has led to the development of novel diagnostic probes. In this text, leading clinicians and scientists present the most current data for the evaluation and classification of leukemias, lymphomas and multiple myeloma."

(Steven T. Rosen, M.D., Series Editor, Cancer Treatment and Research)

From the Publisher

4 Stars! from Doody