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9780849383724
Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal Models and Biomedical Tools / Edition 1 available in Hardcover, eBook
Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal Models and Biomedical Tools / Edition 1
by John P. Sundberg
John P. Sundberg
- ISBN-10:
- 0849383722
- ISBN-13:
- 9780849383724
- Pub. Date:
- 05/19/1994
- Publisher:
- Taylor & Francis
- ISBN-10:
- 0849383722
- ISBN-13:
- 9780849383724
- Pub. Date:
- 05/19/1994
- Publisher:
- Taylor & Francis
Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal Models and Biomedical Tools / Edition 1
by John P. Sundberg
John P. Sundberg
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Overview
Handbook of Mouse Mutations with Skin and Hair Abnormalities presents 48 mouse mutations that are all available to the biomedical community. Many of the mouse mutations with dermatological diseases are reviewed and illustrated in detail. This popular reference book gives you a single source to use when determining which mouse mutation will best serve your needs as a biomedical tool for sophisticated research projects.
The book also includes an overview of domestic animal genodermatoses to provide alternatives to mouse models that do not exist or to complement those that do. A detailed section written by renowned experts compares the biology of human and mouse skin and skin diseases in the areas of development and the use of animal models, mammalian genetics, keratin biochemistry, epidermal and hair follicle cycles and kinetics, cytokines and growth factors, keratinocyte culture systems, cutaneous carcinogenesis, cutaneous immune system, and skin changes associated with mutations of the endocrine system.
The book also includes an overview of domestic animal genodermatoses to provide alternatives to mouse models that do not exist or to complement those that do. A detailed section written by renowned experts compares the biology of human and mouse skin and skin diseases in the areas of development and the use of animal models, mammalian genetics, keratin biochemistry, epidermal and hair follicle cycles and kinetics, cytokines and growth factors, keratinocyte culture systems, cutaneous carcinogenesis, cutaneous immune system, and skin changes associated with mutations of the endocrine system.
Product Details
ISBN-13: | 9780849383724 |
---|---|
Publisher: | Taylor & Francis |
Publication date: | 05/19/1994 |
Series: | CRC Series in Dermatology |
Pages: | 558 |
Product dimensions: | 7.00(w) x 10.00(h) x (d) |
About the Author
John P. Sundberg, D.V.M., Ph.D., is Head of the Pathology program at the Jackson Laboratory in Bar Harbor, Maine. Dr. Sundberg graduated in 1973 from the University of Vermont with a B.S. degree in Animal Science (summa cum laude) and obtained his D.V.M. degree in 1977 from Purdue University School of Veterinary Medicine, West Lafayette, Indiana. Following a brief period in private practice. Dr. Sundberg earned a Ph.D. degree in comparative pathology in 1981 from The University of Connecticut in Storrs. Dr. Sundberg served as an assistant professor at the University of Illinois College of Veterinary Medicine from 1981 to 1986. In 1986 he assumed his present position. Dr. Sundberg is a diplomate of the American College of Veterinary Pathologists. He is a member of the American Veterinary Medical Association, American Association for Laboratory Animal Science, Society for Investigative Dermatology, Hair Research Society, New England Veterinary Pathology Colloquy, and the Maine Veterinary Medical Association. Dr. Sundberg has been the recipient of research grants from the National Institutes of Health, American Cancer Society, National Alopecia Areata Foundation, and private industry. He has published over 125 research and clinical papers, 50 technical bulletins, and 15 book chapters. His current major research interests relate to mouse mutations as models of human and animal diseases, the comparative pathology and molecular evolution of nonhuman papillomaviruses, and spontaneous diseases of inbred laboratory mice.
Table of Contents
PART I. BIOLOGY OF SKIN AND HAIR OF LABORATORY MICE AND HUMAN BEINGS Introduction Chapter 1. Applications and Needs of Models for Dermatological Research /Lowell A. Goldsmith Chapter 2. Inbred Laboratory Mice as AnimaJ Models and Biomedical Tools: General Concepts /John P. Sundberg Chapter 3. The Jackson Laboratory Mouse Mutant Resource /Muriel T. Davisson Chapter 4. Hair Follicle Stem Cells /Robert M. Lavker, Tung-Tien Sun, and John P. Sundberg Chapter 5. The Mouse Skin as a Model for Chemical Carcinogenesis /Claudio J. Conti Chapter 6. Viral Induced Skin Tumors in Mice /John P. Sundberg, Hendrick G. Bedigian, and Roderick Bronson Chapter 7. Hair Types and Subtypes in the Laboratory Mouse /John P. Sundberg and Margaret E. Hogan Chapter 8. Growth Factors and Cutaneous Pathology /Lloyd E. King, Jr., Lillian B. Nanney, and Ronald E. Gates Chapter 9. Transgenic Mice with Cytokine Mutations Affecting the Skin /Manfred Blessing, Erby Wilkinson, and Brigid L. M. Hogan Chapter 10. Epidermal Keratins /Joseph A. Rothnagel and Dennis R. Roop Chapter 1 1. Hair Follicle Keratins /George E. Rogers and Barry C. Powell Chapter 12. Keratinocyte Cultures as Models for DermatologicaJ Disease /Mark R. Pittelkow Chapter 13. Mouse Mutations with Endocrine Functional Consequences /Wesley G. Beamer Chapter 14. The Immune System in Cutaneous Disease: the Search for a Mouse Model of the Lmmunopathology of Psoriasis /Susan F. Grammer and J. Wayne Streilein PART II. ANIMAL MODELS OF GENETIC BASED SKIN DISEASES Section A. Mouse Single Gene Mutations Introduction Chapter 1. The Adrenocortical Dysplasia (acd) Mutation, Chromosome 8 /John P. Sundberg, Seth J. Orlow, Hope O. Sweet, and Wesley G. Beamer Chapter 2. The Angora (go) Mutation, Chromosome 5 /John P. Sundberg Chapter 3. The Asebia (ab, ab1) Mutations, Chromosome 19 /John P. Sundberg Chapter 4. The Atrichosis (at) Mutation, Chromosome 10 /John P. Sundberg Chapter 5. The Balding (bal) Mutation, Chromosome 18 /John P. Sundberg Chapter 6. The Bare-Patches (Bpa) Mutation, Chromosome X /John P. Sundberg Chapter 7. The Bareskin (Bsk) Mutation, Chromosome 11 /John P. Sundberg Chapter 8. The Beige (bg) Mutation, Chromosome 13 /John P. Sundberg Chapter 9. The Caracul (Ca and Cad) Mutations, Chromosome 15 /John P. Sundberg and Hope O. Sweet Chapter 10. The Chronic Proliferative Dermatitis (cpd) Mutation, Chromosome? Harm HogenEsch, Marion J. J. Gijbels, and Chris Zurcher Chapter 11. The Crinkled (cr) Mutation, Chromosome 13 /John P. Sundberg Chapter 12. The Curly-Whiskers (cw) Mutation, Chromosome 9 /John P. Sundberg Chapter 13. The Depilated (dep) Mutation, Chromosome 4 /John P. Sundberg and Seth J. Orlow Chapter 14. The Downless (dl) and Sleek (Dlslk) Mutations, Chromosome 10 /John P. Sundberg Chapter 15. The Ferrochelatase Deficiency (FechmlPas) Mutation, Chromosome 18 /Xavier Montagutelli Chapter 16. The Flaky Skin (fsn) Mutation, Chromosome? /John P. Sundberg, Dawnalyn Boggess, Leonard D. Shultz, and Wesley G. Beamer Chapter 17. The Flaky Tail (ft) Mutation, Chromosome 3 /John P. Sundberg Chapter 18. The Frizzy (fr) Mutation, Chromosome 7 /John P. Sundberg Chapter 19. The Fuzzy (fz) Mutation, Chromosome 1 /John P. Sundberg Chapter 20. The Greasy (Gs) Mutation, Chromosome X /John P. Sundberg Chapter 21. The Hair Interior Defect (hid) Mutation, Chromosome? /John P. Sundberg Chapter 22. The Hairless (hr) and Rhino (hrrh) Mutations, Chromosome 14 /John P. Sundberg Chapter 23. The Hair Patches (Hpt) Mutation, Chromosome 4 /John P. Sundberg Chapter 24. The Hairy Ears (Eh) Mutation, Chromosome 15 /John P. Sundberg and Seth J. Orlow Chapter 25. The Harlequin (Hq) Mutation, Chromosome X /John P. Sundberg Chapter 26. The Ichthyosis (ic) Mutation, Chromosome 1 /John P. Sundberg and Mark R. Pittelkow Chapter 27. The Lethal Milk (Im) Mutation, Chromosome 2 /John P. Sundberg and Hope O. Sweet Chapter 28. The Lustrous ( / /) Mutation, Chromosome 11 /John P. Sundberg Chapter 29. The Matted (ma) Mutation, Chromosome 3 /John P. Sundberg Chapter 30. The Motheaten (me) and Viable Motheaten (mev) Mutations, Chromosome 6 /Leonard D. Shultz and John P. Sundberg Chapter 31. The Mottled Locus: Mottled (Mo), Blotchy (Mobl°), Brindled (Mobr), Dappled (Modp), Mosaic (Moms), Tortoiseshell (Mow), and Viable Brindled (Movbr) Mutations, Chromosome X / John P. Sundberg Chapter 32. The Naked (N) Mutation, Chromosome 15 /John P. Sundberg Chapter 33. The Nude (nu) and Streaker (nustr) Mutations, Chromosome 11 /John P. Sundberg Chapter 34. The Ragged (Ra) and Opossum (Raop) Mutations, Chromosome 2 /John P. Sundberg Chapter 35. The Repeated Epilation (Er) Mutation, Chromosome 4 /Jean-Louis Guenet, Josselyne Salaun, and Berthe Salzgeber Chapter 36. The Rex (Re), Wavy Coat (Rewl), and Denuded (Reden) Mutations, Chromosome 11 /John P. Sundberg Chapter 37. The Satin (sa) Mutation, Chromosome 13 /John P. Sundberg Chapter 38. The Scurfy (sf) Mutation, Chromosome X /Virginia L. Godfrey Chapter 39. The Severe Combined Immunodeficiency (scid) Mutation, Chromosome 16 /John P. Sundberg and Leonard D. Shultz Chapter 40. The Shaven (Sha) Mutation, Chromosome 15 /John P. Sundberg Chapter 41. The Silver (si) Mutation, Chromosome 10 /Seth J. Orlow and John P. Sundberg Chapter 42. The Soft Coat (soc) Mutation, Chromosome 3 /John P. Sundberg Chapter 43. The Sparse-Coat (spc) Mutation, Chromosome 14 /John P. Sundberg Chapter 44. The Sparse-Fur (Otcspf) and Abnormal Skin and Hair (Otcash) Mutations, Chromosome X /John P. Sundberg and Donald P. Doolittle Chapter 45. The Tabby (Ta), Tabby-c (Tal), and Tabby-J (TaJ) Mutations, Chromosome X /John P. Sundberg Chapter 46. The Tight-Skin (Tsk) Mutation, Chromosome 2 /John P. Sundberg Chapter 47. The Vitiligo (mivu) Mutant Allele of the Microphthalmia Locus, Chromosome 6 /M. Lynn Lamoreux and Seth J. Orlow Chapter 48. The Wellhaarig (we, weMr) Mutations, Chromosome 2 /John P. Sundberg Section B. Purported Polygenic Mouse Skin Diseases Introduction Chapter 1. Chronic Ulcerative Dermatitis in Black Mice /John P. Sundberg, Kathy S. Brown, and William M. McMahon Chapter 2. Barbering Behavioral Abnormalities in Inbred Laboratory Mice /William M. McMahon and John P. Sundberg Chapter 3. Alopecia Areata in Aging C3H /HeJ Mice /John P. Sundberg, Colleen M. Vallee, and Lloyd E. King, Jr. Section C. Nonmurine Animal Models of Genetic Based Skin Diseases Chapter 1. Selected Heritable Skin Diseases of Domesticated Animals /Robert W. Dunstan and Robert A. Kennis Index.From the B&N Reads Blog
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