DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression

DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression begins with an historical overview of the early discoveries surrounding DNA methylation in the mammalian brain and then explores the evidence supporting a role for this epigenetic mechanism in controlling gene expression programs across the lifespan in both normal and diseased states.

Chapters describe new directions and technological advances, and provide an overview of what the future holds for this exciting new field. This book is ideal for medical, graduate and advanced undergraduate students, but is also a great resource for researchers who need a broad introduction to the dynamic nature of DNA that sheds light on evolving concepts of gene-environment interaction and their effects on adaptation and neuropsychiatric disease.

  • Provides a comprehensive overview of the many facets of DNA modifications
  • Discusses the impact of this dynamic epigenetic mechanism across brain development and lifespan at behavioral, cognitive, molecular and genetic levels
  • Contains contributions by influential leaders in the field
  • Edited by a Neuroscientist to further promote synthesis between epigenetics, neuroscience, and clinical relevance
1132568568
DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression

DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression begins with an historical overview of the early discoveries surrounding DNA methylation in the mammalian brain and then explores the evidence supporting a role for this epigenetic mechanism in controlling gene expression programs across the lifespan in both normal and diseased states.

Chapters describe new directions and technological advances, and provide an overview of what the future holds for this exciting new field. This book is ideal for medical, graduate and advanced undergraduate students, but is also a great resource for researchers who need a broad introduction to the dynamic nature of DNA that sheds light on evolving concepts of gene-environment interaction and their effects on adaptation and neuropsychiatric disease.

  • Provides a comprehensive overview of the many facets of DNA modifications
  • Discusses the impact of this dynamic epigenetic mechanism across brain development and lifespan at behavioral, cognitive, molecular and genetic levels
  • Contains contributions by influential leaders in the field
  • Edited by a Neuroscientist to further promote synthesis between epigenetics, neuroscience, and clinical relevance
74.99 In Stock
DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression

DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression

by Timothy W Bredy (Editor)
DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression

DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression

by Timothy W Bredy (Editor)

eBook

$74.99  $99.95 Save 25% Current price is $74.99, Original price is $99.95. You Save 25%.

Available on Compatible NOOK devices, the free NOOK App and in My Digital Library.
WANT A NOOK?  Explore Now

Related collections and offers


Overview

DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression begins with an historical overview of the early discoveries surrounding DNA methylation in the mammalian brain and then explores the evidence supporting a role for this epigenetic mechanism in controlling gene expression programs across the lifespan in both normal and diseased states.

Chapters describe new directions and technological advances, and provide an overview of what the future holds for this exciting new field. This book is ideal for medical, graduate and advanced undergraduate students, but is also a great resource for researchers who need a broad introduction to the dynamic nature of DNA that sheds light on evolving concepts of gene-environment interaction and their effects on adaptation and neuropsychiatric disease.

  • Provides a comprehensive overview of the many facets of DNA modifications
  • Discusses the impact of this dynamic epigenetic mechanism across brain development and lifespan at behavioral, cognitive, molecular and genetic levels
  • Contains contributions by influential leaders in the field
  • Edited by a Neuroscientist to further promote synthesis between epigenetics, neuroscience, and clinical relevance

Product Details

ISBN-13: 9780128017814
Publisher: Elsevier Science
Publication date: 12/23/2016
Sold by: Barnes & Noble
Format: eBook
Pages: 180
File size: 16 MB
Note: This product may take a few minutes to download.

About the Author

Dr. Timothy Bredy is Associate Professor of Neuroscience in the Ayala School of Biological Sciences at the University of California Irvine and Senior Research Fellow within the Queensland Brain Institute at the University of Queensland.

Table of Contents

1. History and Modern View on DNA Modifications in the Brain 2. Approaches to Detecting DNA Base Modification in the Brain 3. Active DNA Demethylation in Neurodevelopment 4. TET and 5hmC in Neurodevelopment and the Adult Brain 5. Beyond mCG: DNA Methylation in Noncanonical Sequence Context 6. DNA Modifications and Memory 7. Measuring CpG Methylation by SMRT Sequencing 8. Epigenetic Modifications of DNA and Drug Addiction 9. What Does the Future Hold for the Study of Nucleic Acid Modifications in the Brain?

What People are Saying About This

From the Publisher

A comprehensive reference on the role of the epigenome in gene expression and brain function in both normal and diseased states

From the B&N Reads Blog

Customer Reviews