Disorders of Neuronal Migration / Edition 1

by Peter G. Barth, Isabelle Rapin, Peter G. Procopis

Overview

Disorders of neuronal migration can cause learning disability, autism, and epilepsy. Many are genetically determined and need precise diagnosis to provide genetic counselling. This book will help the clinician to acquire insight as well as proficiency in diagnosis. Individual chapters describe subgroups including lissencephalies, subependymal heterotopia, non-lissencephalic cortical dysplasias, anomalies of the corpus callosum, hemimegalencephaly, schizencephaly, polymicrogyria and multisystem disorders with impaired migration such as chromosomal and metabolic syndromes. Neuroradiological and genetic data are provided with the respective chapters. Although the book is intended for clinical practice, it provides core information for all interested in this important biological process.

Product Details

ISBN-13:	9781898683315
Publisher:	Wiley
Publication date:	01/17/2003
Series:	International Child Neurology Association Series
Pages:	220
Product dimensions:	6.14(w) x 9.21(h) x 0.56(d)

About the Author

Edited by Peter G. Barth, Universiteit van Amsterdam

Table of Contents

1. Introduction Peter G. Barth; 2. Morphogenesis of the human cerebral cortex V. S. Caviness Jr, T. Takahashi, R. S. Nowakowski and Robert Wood; 3. Lissencephaly: the clinical and molecular genetic basis of diffuse malformations of neuronal migration William B. Dobyns and Richard J. Leventer; 4. Non-lissencephalic cortical dysplasias Ruben I. Kuzniecky and Frederick Andermann; 5. Periventricular gray matter heterotopia: a heterogenous group of malformations of cortical development Richard J. Leventer and William B. Dobyns; 6. Anomalies of the Corpus Callosum and cortical malformations A. James Barkovich; 7. Hemimegalencephaly Laura Flores-Sarnat; Index.

Editorial Reviews

Reviewer: Michael G White, MD (Ochsner Clinic Foundation)
Description: This volume in the International Review of International Review of Child Neurology Series covers the current literature regarding disorders of neuronal cell migration, including research into how these disorders develop and the clinical implications of the process.
Purpose: The impetus for this book was an international symposium in 1998 examining the clinical implications of abnormal neuronal migration. The book reviews and updates the information presented at that symposium. It covers the area of interest well.
Audience: The book is written for neurologists and others with an interest in the clinical manifestations of abnormal neuronal migration. It is presented in the style of scientific reviews incorporating extensive references to current literature and reads well for a book of this genre. It is not light reading, but it does cover the material well enough to avoid overwhelming less knowledgeable readers.
Features: The book includes chapters written by experts in topics related to clinical conditions arising from disorders of neuronal migration. The style is a typical presentation of a specific area of interest at the clinical and experimental interface. It is a good source of information for those interested in this topic, but would not be recommended for a quick review of the subject.
Assessment: This is a typical review book of a relatively specific subject and it would serve as a good beginning for those interested in learning more about this group of neurological problems.

Doody's Review Service

3 Stars from Doody