Containment in the Pharmaceutical Industry / Edition 1

by James P. Wood

Overview

Delivering an encompassing overview of the factors, varieties, and applications determining product containment, this concise reference provides authoritative information on containment processes. It reviews the historical context, definition, evolution, and application of containment technology, analyzes a variety of containment techniques in new and retrofitted construction, and examines "people protection" vs. "product protection" and the role of source-contamination in each. It also suggests conceptualizing containment options from the inception of a project for economical, at-the-source containment, identifies containment requirements and monitoring methods, as well as the current state of emission controls, and discusses the "dustiness" of powders and how this research is being defined, quantified, and used in containment design.

Product Details

ISBN-13:	9780824703974
Publisher:	Taylor & Francis
Publication date:	09/25/2000
Series:	Drugs and the Pharmaceutical Sciences , #108
Edition description:	New Edition
Pages:	272
Product dimensions:	6.00(w) x 9.00(h) x (d)

About the Author

JAMES P. WOOD is an Associate Engineering Consultant with the Containment Engineering Technology Group of Eli Lilly and Company, Indianapolis, Indiana. An advisor to many international organizations, Mr. Wood is the author or coauthor of numerous articles, patents, and presentations related to containment issues, and a member of the National Society of Professional Engineers. He received the B.S. degree (1979) from Purdue University, West Lafayette, Indiana.

Table of Contents

Why containment? Then and now; containment and good manufacturing practices; industrial hygiene aspects of pharmaceutical manufacturing; effect of individual particle characteristics on airborne emissions; particle monitoring - old and new; particle monitoring - case studies; selecting the correct technology; engineered local exhaust; flexible containment for primary manufacturing/bulk operations; an array of containment design - following the production line in a dry products secondary manufacturing operation; containment system selection; an architectural/engineering firm's perspective; containment in the hospital setting.

Editorial Reviews

..present[s] not only up-to-date information, but also timeless approaches and advice.... An excellent reference source of practical and up-to-date information.

Journal of Loss Prevention In the Process Industries

...can be regarded as a tool...useful in the quest to better contain pharmaceutical operations.
—European Journal of Pharmaceutics and Biopharmaceutics

Publisher

Thirteen chapters explore the main elements and applications of containment as it is currently practiced by members of the pharmaceutical industry. The book first presents a brief historical perspective on containment in the industry, a workable definition of the term, and containment's relationship to other industries. Along with definitions, one chapter focuses on recent research of what makes powders dusty in the first place and how that is being defined, quantified, and used in containment design. The contributors also discuss approaches for both new and retrofitted installations, and people protection versus product protection along with source containment's potential role in each. Topics include engineered local exhaust, flexible containment for primary manufacturing/bulk operations, the production line of a dry products secondary manufacturing operation, and containment in the hospital setting. Annotation c. Book News, Inc., Portland, OR (booknews.com)

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