Cell and Molecular Biology of the Testis / Edition 1

by Claude Desjardins, Larry L. Ewing

Overview

This book is a comprehensive, multi-authored work on the structure and function of the mammalian testis. The approach emphasizes gene expression, translation and production of specific gene products and the cellular and molecular regulation of these fundamental processes. Rather than provide a global survey of all aspects of male reproduction, this book stresses specific mechanisms that underscore the structure and function of the testis. It explains old and new concepts from a cellular and molecular perspective. This novel approach allows the authors to forge links between cell and molecular biology and well-established aspects of spermatogenesis and steroidogenesis. The result is a well-focused, comprehensive, and synthetic analysis of testicular biology.

Product Details

ISBN-13:	9780195062694
Publisher:	Oxford University Press
Publication date:	09/30/1993
Edition description:	New Edition
Pages:	512
Product dimensions:	7.63(w) x 12.63(h) x 1.59(d)

About the Author

Desjardins, Claude, PhD (Univ of Virginia); Ewing, Larry L., PhD (Johns Hopkins Univ)

The contributors are basic scientists from academic institutions in the U.S. (Johns Hopkins, Columbia, M.D. Anderson, Univ of Virginia), Canada (McGill Univ), the U.K., France, and Australia. They are anatomists, geneticists, reproductive and developmental biologists, and surgeons.

Table of Contents

1. Cell Biology of Testicular Development in the Fetus and Neonate, J.M. Orth2 Molecular Genetics of the Human and Mouse Y-Chromosome, P.N. Goodfellow, et al.3. Development of the Germ Cell, J.R. McCarrey4. Genetic Control of Spermatogenesis and Steroidogenesis, C.E. Chubb5. Mullerian Inhibiting Substance, P.K. Donahoe6. Design and Function of the Microcirculation, C. Desjardins7. Leydig Cell:Structure/Function, L.L. Ewing8. Regulation of Spermatogenesis in the Adult Mammal: Gonadotropins and Androgens, B.R. Zirkin9. The Cell Biology of the Sertoli Cell, C.W. Bardin, G. L. Gunsalus and C.Y. Cheng10. Inhibin and Inhibin-related Proteins, D.M. Robertson, G.P. Risbridger, and D.M. de Kretser11. The Seminiferous Tubular Microenvironment, B.T. Hinton and T.T. Turner12. Spermatogonial Stem Cells, M.L. Meistrich and M.E.A.B. van Beek13. The Process of Meiosis, H. Stern14. Cell Biology of Mammalian Spermiogenesis, Y. Clermont, R. Oko, and L. Hermo15. Cellular Interactions in the Seminiferous Epithelium, W.W. Wright16. Gene Expression During Male Germ Cell Development, N. Hecht17 Patterns of Expression and Potential Functions of Cellular Oncogenes and Heat Shock Protein Genes During Germ Cell Development, D.J. Wolgemuth, et al.18. Sperm Cell Surface Proteins of Testicular Origin: Expression and Localization in the Testis and Beyond, D.G. Myles19. Regulation of Autoimmune Disease, K.S.K. Tung

Editorial Reviews

Reviewer: Alvin Telser, PhD (Northwestern University Feinberg School of Medicine)
Description: This is a comprehensive and current treatise on the cell and molecular biology of the mammalian testis. It is well written, well edited, and of high quality both from a content and physical point of view.
Purpose: The book is intended to combine cellular, molecular, genetic, physiologic, and developmental facts and concepts about the testes for workers in the field and for those who may need an authoritative reference or who may wish to learn about this aspect of reproductive biology. These objectives are achieved to a significant degree in this monograph.
Audience: The book is written for researchers in this field and for those who may wish to learn more about the field. There is a high probability that the book will become the major reference in the cell and molecular biology of the testes for the next several years.
Features: The book has no special distinctive features. The graphs and line drawings are clear, accurate, and easy to interpret. The smaller number of light and electron micrographs are of a good, but not exceptional, quality. Most chapters have an appropriate number of illustrations; others might benefit from a greater number of diagrams.
Assessment: This is an excellent book that is likely to become the standard reference in its field during the next five years or so. It combines a wide range of contemporary knowledge about and approaches to the biology of the testes. Libraries should find this monograph to be a valuable addition to their collection on modern approaches to and knowledge of traditional areas of human biology.

Doody's Review Service

5 Stars! from Doody

This is a comprehensive and current treatise on the cell and molecular biology of the mammalian testis. It is well written, well edited, and of high quality both from a content and physical point of view. "The book is intended to combine cellular, molecular, genetic, physiologic, and developmental facts and concepts about the testes for workers in the field and for those who may need an authoritative reference or who may wish to learn about this aspect of reproductive biology. These objectives are achieved to a significant degree in this monograph. "The book is written for researchers in this field and for those who may wish to learn more about the field. There is a high probability that the book will become the major reference in the cell and molecular biology of the testes for the next several years. "The book has no special distinctive features. The graphs and line drawings are clear, accurate, and easy to interpret. The smaller number of light and electron micrographs are of a good, but not exceptional, quality. Most chapters have an appropriate number of illustrations; others might benefit from a greater number of diagrams. "This is an excellent book that is likely to become the standard reference in its field during the next five years or so. It combines a wide range of contemporary knowledge about and approaches to the biology of the testes. Libraries should find this monograph to be a valuable addition to their collection on modern approaches to and knowledge of traditional areas of human biology.

Alvin Telser