Brain Control of Responses to Trauma / Edition 1

by Nancy J. Rothwell, Frank Berkenbosch

Overview

It is becoming increasingly clear that the brain has an important role in the control and integration of the responses to injury and infection. This is the first volume to look in depth at the way the brain responds to trauma and subsequently integrates and influences behavioral, metabolic, neurohumoral, cardiovascular, and immune functions. It is well established that some of these responses, such as fever and neuroendocrine changes are directly influenced by the central nervous system. These, and other more recent advances, provide new insights into this area and provide a basis for more effective understanding and clinical management of trauma patients. The authors, all international authorities in their fields, discuss established and recent data from experimental and clinical studies and consider the implications of these findings for the treatment of the trauma patient. This book will serve as an excellent reference for professionals who deal with trauma or who work in accident and emergency medicine, neuroscience, neuroimmunology and physiology.

Product Details

ISBN-13:	9780521419390
Publisher:	Cambridge University Press
Publication date:	09/15/1994
Edition description:	New Edition
Pages:	354
Product dimensions:	6.14(w) x 9.29(h) x 0.98(d)

About the Author

Rothwell, Nancy J. (Univ of Manchester); Berkenbosch, Frank (Free Univ of Amsterdam)

The contributors represent the specialties of pharmacology, immunology, physiology, environmental science, injury research, psychiatry, and psychology. All come from hospitals and medical centers in Europe and North America. Institutions prominently represented include Univ of Manchester, The Free Univ in Amsterdam, Emory, Univ of Manitoba, and Univ of Bergen.

Table of Contents

1. Introduction N. J. Rothwell; 2. Overview of responses to injury B. Stonar; 3. Experimental approaches to the study of CNS control of responses to injury N. J. Rothwell and R. Little; 4. CNS control and neural mediations of immune responses and inflammation D. Payan; 5. Neurohormonal control of cytokines during injury I. Berczi; 6. Brain regions involved in modulation of immune responses P. Neveu; 7. Psychological and neurobiological consequences of trauma C. Nemeroff; 8. CNS control of sickness behaviour Robert Dantzer; 9. Psychological and behavioural aspects of pain H. Ursin; 10. Central control of cardiovascular responses to injury R. Little and E. Kirkman; 11. Endocrine/neuroendocrine responses to trauma F. Berkenbosch; 12. Central control of the metabolic and thermoregulatory responses to injury N. J. Rothwell; 13. Central control of pain R. W. Clarke; Index.

Editorial Reviews

"This is a notable contribution, of wider potential clinical interest than might appear, since virtually all types of bodily insult or damage rather than 'trauma' in the sense only of injury, are brought into the same integrative perspective." Sheila Jennett, Journal of the Royal Society of Medicine

"...an interesting approach to the primarily chemical study of cerebral tissue responses to trauma." Electroencephalography and Clinical Neurophysiology

From the Publisher