Apoptosis Genes / Edition 1

by James W. Wilson, Catherine Booth, Christopher S. Potten

Overview

This useful work presents a current overview of key genes involved in the control of apoptosis research together with thoughts on future prospects and clinical applications. While there are several books written on apoptosis, this one deals specifically with its regulation.

Product Details

ISBN-13:	9780412838606
Publisher:	Springer US
Publication date:	01/31/1999
Edition description:	1998
Pages:	310
Product dimensions:	6.10(w) x 9.25(h) x 0.03(d)

Table of Contents

The role of p53 in apoptosis.- Mammalian bcl-2 family genes.- Stress-responsive signal transduction: emerging concepts and biological significance.- Control of Apoptosis Through Gene Regulation.- Adhesion and Apoptosis.- Death signalling in C. elegans and activation mechanisms of caspases.- Apoptosis in Drosophila.- Viral genes that modulate apoptosis.- Therapeutic manipulation of apoptosis in cancer and neurological disease.

Editorial Reviews

Ten contributions present an overview of the genes involved in the control of apoptosis along with a history of apoptosis research, its clinical applications, and its future prospects. Topics include the role of p53 in apoptosis; mammalian family genes; stress- responsive signal transduction; control of apoptosis through gene regulation; adhesion and apoptosis; death signaling in C. and activation mechanisms of caspases; apoptosis in Drosophila; viral genes that modulate apoptosis; and therapeutic manipulation of apoptosis in cancer and neurological disease. Annotation c. Book News, Inc., Portland, OR (booknews.com)

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