Tobacco-Specific N-Nitrosamines Recent Advances

by Roger O. McClellan

Overview

This remarkable book provides updates on various aspects of tobacco - its chemical and biological nature, and its physiological effects.

Product Details

ISBN-13:	9781351408073
Publisher:	CRC Press
Publication date:	10/06/2017
Sold by:	Barnes & Noble
Format:	eBook
Pages:	85
File size:	4 MB

About the Author

McClellan, Roger O.

Table of Contents

1. Introduction 2. Formation and Analysis of Tobacco-Specific N-Nitrosamines 3. Synthesis of Tobacco-Specific N-Nitrosamines and Their Metabolites and Results of Related Bioassays 4. Endogenous Formation of Nitrosamines and Oxidative DNA-Damaging Agents in Tobacco Users 5. Recent Studies on Mechanisms of Bioactivation and Detoxification of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone (NNK), A Tobacco-Specific Lung Carcinogen 6. Epidemiology of Cancer by Tobacco Products and the Significance of TSNA 7. The Biological Significance of Tobacco-Specific N-Nitrosamines: Smoking and Adenocarcinoma of the Lung 8. Comparative Carcinogenicity, Metabolism, Mutagenicity, and DNA Binding of 7H-Dibenzo[c,g]carhazole and Dibenz[a,j]acridine 9. Concluding Remarks