Thrombin

Thrombin

by Lawrence J. Berliner (Editor)
Thrombin

Thrombin

by Lawrence J. Berliner (Editor)

Hardcover

$289.00 
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Overview

This comprehensive treatise details the structure, biochemistry, and physiology of thrombin, including detailed three-dimensional X-ray structures of inhibited human thrombin complexes. It is both well-illustrated and well-referenced to provide the physiologist and the biochemist with a first-rate sourcebook.


Product Details

ISBN-13: 9780306439919
Publisher: Springer-Verlag New York, LLC
Publication date: 01/28/1992
Pages: 354
Product dimensions: 6.69(w) x 9.45(h) x (d)

About the Author

Dr. Lawrence J. Berliner is currently Professor and Chair of the Department of Chemistry and Biochemistry at the University of Denver after retiring from Ohio State University, where he spent a 32-year career in the area of biological magnetic resonance (EPR and NMR). He is the Series Editor for Biological Magnetic Resonance, which he launched in 1979.

Table of Contents

Structure: Nuclear Magnetic Resonance Studies of ThrombinFibrinopeptide and ThrombinHirudin Complexes (F. Ni et al.). ESR and Flourescence Studies of Thrombin Active Site Conformation (L.J. Berliner). Biochemistry: Synthetic Substrates and Inhibitors of Thrombin (J.C. Powers, C.M. Kam). Regulation of Thrombin by Antithrombin and Heparin Cofactor II (S.T. Olson, I. Björk). Hirudin Interactions with Thrombin (S.R. Stone, J.M. Maraganore). Physiology: Functional Domains in Thrombin Outside the Catalytic Site (R. BarShavit et al.). Post Clotting Cellular Effects of Thrombin Mediated by Interaction with HighAffinity Thrombin Receptors (D.H. Carney). Regulation of ThrombinInduced Endothelial Barrier Dysfunction and Prostaglandin Synthesis (J.G.N. Garcia et al.). 3 additional articles. Index.

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