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The Treatment of Epilepsy
1072![The Treatment of Epilepsy](http://img.images-bn.com/static/redesign/srcs/images/grey-box.png?v11.9.4)
The Treatment of Epilepsy
1072eBook
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Overview
- The text is compiled by a group of internationally renowned editors and contributors and is now in full color and extensively illustrated
- The first two sections cover the background to, and principles of, treatment in different clinical situations
- Section three comprises a series of systematic reviews of contemporary drug therapy, devoting one chapter to each anti-epileptic drug and covering all clinically-relevant aspects
- Section four focuses on the surgical options, devoting individual chapters to each of the modalities of presurgical assessment and to each surgical operation or approach
- This 4th edition is extensively revised incorporating the many recent developments in therapy, and comprises 81 chapters from world experts from 18 countries
Product Details
ISBN-13: | 9781118936993 |
---|---|
Publisher: | Wiley |
Publication date: | 09/23/2015 |
Sold by: | JOHN WILEY & SONS |
Format: | eBook |
Pages: | 1072 |
File size: | 25 MB |
Note: | This product may take a few minutes to download. |
About the Author
Emilio Perucca MD PhD FRCP(Edin)Professor of Medical Pharmacology, Clinical Pharmacology Unit, Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy; and Director, Clinical Trial Center, C Mondino National Neurological Institute, Pavia, Italy
Jerome Engel Jr MD PhDDirector, Seizure Disorder Center, Jonathan Sinay Distinguished Professor, Neurology, Neurobiology, Psychiatry and Behavioural Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
Table of Contents
List of ContributorsPreface to the Fourth Edition
Preface to the First Edition
Historical Introduction: The Drug Treatment of Epilepsy from 1857 to 2015 Simon Shorvon
Section IIntroduction (Lead editor: Simon Shorvon)
1 Definition (Terminology) and Classification in Epilepsy: A Historical Survey and Current Formulation, with Special Reference to the ILAE 1Simon Shorvon
2 Differential Diagnosis of Epilepsy 24Mark Cook
3 Mechanisms of Epileptogenesis 38Giuliano Avanzini and Silvana Franceschetti
4 Antiepileptic Drug Discovery 52H. Steve White and Melissa Barker-Haliski
5 Antiepileptic Drug Development 61Dieter Schmidt
6 Mechanisms of Antiepileptic Drug Action 75Matthew C. Walker and Rainer Surges
7 Mechanisms of Drug Resistance and Tolerance 92Wolfgang Loscher and Dieter Schmidt
8 Epilepsy Biomarkers 103Jerome Engel, Jr. and Asla Pitkanen
Section IIPrinciples of Medical Management (Lead editor: Simon Shorvon)
9 General Principles of Medical Management 110Emilio Perucca
10 Pharmacokinetic Optimization of Therapy 124Svein I. Johannessen, Cecilie Johannessen Landmark and Emilio Perucca
11 Management of Chronic Active Epilepsy in Adults 139Simon Shorvon
12 Management of Epilepsy in Remission 148Patrick Kwan, Howan Leung and Xiaoting Hao
13 Management of Epilepsy in Neonates and Infants 156Elissa G. Yozawitz and Solomon L. Moshe
14 Management of Childhood Epilepsy Syndromes 174Colin D. Ferrie
15 Management of Epilepsy in People with Intellectual Disabilities 193Eylert Brodtkorb
16 Management of Epilepsy in the Elderly 205Hiba Arif Haider and Lawrence J. Hirsch
17 Emergency Treatment of Seizures and Status Epilepticus 221Matthew C. Walker and Simon Shorvon
18 Management of Medical Comorbidity Associated with Epilepsy 245Gagandeep Singh
19 Psychiatric Features of Epilepsy and their Management 259Brent Elliott and Simon Shorvon
20 Prevention and Management of Side-effects of Antiepileptic Drugs 275Gaetano Zaccara and Piero Perucca
21 Ketogenic Diets 288Eric H. Kossoff and Courtney A. Haney
22 Complementary and Alternative Treatments for Epilepsy 298Sallie Baxendale
23 Reproductive Aspects of Epilepsy Treatment 311Torbjorn Tomson
24 Genetic Counselling in Epilepsy 323Federico Zara
25 Drug Interactions 344Edoardo Spina and Domenico Italiano
26 Medical Treatment of Epilepsy in Resource-Poor Countries 360Patrick Adjei
Section IIIAntiepileptic Drugs (Lead editor: Emilio Perucca)
27 Introduction to the Choice of Antiepileptic Drugs 365Emilio Perucca
28 Acetazolamide 376Miri Y. Neufeld
29 Adrenocorticotropic Hormone and Corticosteroids 388Federico Vigevano and Maria Roberta Cilio
30 Benzodiazepines Used in the Treatment of Epilepsy 398Eugen Trinka and Francesco Brigo
31 Brivaracetam 418Joseph D'Souza and Emilio Perucca
32 Carbamazepine 431Torbjorn Tomson and Svein I. Johannessen
33 Eslicarbazepine Acetate 447Meir Bialer and Christian Elger
34 Ethosuximide 460Tracy A. Glauser and Emilio Perucca
35 Felbamate 472Ilo E. Leppik and James R. White
36 Gabapentin 479Ernest R. Somerville, Andrew W. Michell and Arjune Sen
37 Lacosamide 489Rajesh Sachdeo and Roopal Karia
38 Lamotrigine 498Awais Riaz and Fumisuke Matsuo
39 Levetiracetam 516Derek J. Chong and Jacqueline A. French
40 Oxcarbazepine 533Edward Faught and Hyunmi Kim
41 Perampanel 546Martin Brodie
42 Phenobarbital, Primidone and Other Barbiturates 555Roberto Michelucci and Elena Pasini
43 Phenytoin 574Mervyn J. Eadie
44 Piracetam 589Simon D. Shorvon
45 Pregabalin 595Sylvain Rheims and Philippe Ryvlin
46 Retigabine 606Michel Baulac
47 Rufinamide 617Victor Biton
48 Stiripentol 628Tapani Keranen
49 Tiagabine 633Reetta Kalviainen
50 Topiramate 642J. Helen Cross and Catherine J. Riney
51 Valproate 652Anthony G. Marson and Graeme J. Sills
52 Vigabatrin 667Gunter Kramer and Gabriele Ch. Wohlrab
53 Zonisamide 680Michel Baulac
54 Other Less Commonly Used Antiepileptic Drugs 689Martin Holtkamp
55 Drugs in Clinical Development 701Norman Delanty and H. Steve White
Section IVPresurgical Assessment and Epilepsy Surgery (Lead editor: Jerome Engel, Jr.)
56 Overview of Surgical Treatment for Epilepsy 709Jerome Engel, Jr.
57 Scalp EEG in the Epilepsy Surgery Evaluation 723Christine B. Baca and John M. Stern
58 Invasive EEG in Presurgical Evaluation of Epilepsy 733Dennis Spencer, Dang K. Nguyen and Adithya Sivaraju
59 MEG in Epilepsy Surgery Evaluation 756Hermann Stefan and Paul Boon
60 MRI in Presurgical Evaluation 764Christian E. Elger and Bernd Weber
61 PET and SPECT in Presurgical Evaluation of Epilepsy 775Karolien Goffin and Wim Van Paesschen
62 Special Neurophysiological Techniques 787Francois Mauguiere and Julien Jung
63 Neuropsychological Testing in Presurgical Evaluation 804Marilyn Jones-Gotman and Gail L. Risse
64 Presurgical Psychiatric Evaluation 817Andres M. Kanner
65 Mesial Temporal Lobe Surgery and Other Lobar Resections 829James Leiphart and Itzhak Fried
66 Resective Surgery of Neoplasms 842Nicholas M. Wetjen and Gregory D. Cascino
67 Resective Surgery of Vascular and Infective Lesions for Epilepsy 858Christopher E. Uff and Neil D. Kitchen68 Surgery of Developmental Anomalies Causing Epilepsy 878Ahyuda Oh, Joshua J. Chern and Youssef G. Comair
69 Hemispheric Operations for Epilepsy 887Georg Dorfmuller, Christine Bulteau and Olivier Delalande
70 Corpus Callosum Operations 895David W. Roberts
71 Hypothalamic Hamartoma 903John F. Kerrigan
72 Multiple Subpial Transection 916Adriana Bermeo-Ovalle and Michael C. Smith
73 Awake Surgery for Epilepsy 922Webster H. Pilcher
74 Epilepsy Surgery in Children 931Jason S. Hauptman and Gary W. Mathern
75 Complications of Epilepsy Surgery 941Charles E. Polkey
76 Anaesthesia for Epilepsy Surgery 952Barbara M. Van de Wiele
77 Vagus and Trigeminal Nerve Stimulation 959Steven C. Schachter
78 Brain Stimulation for Epilepsy 967Gregory K. Bergey and Robert S. Fisher
79 Non-Resective Approaches for Medically Intractable Epilepsy 980Thomas J. Gianaris, Andrea G. Scherer and Nicholas M. Barbaro
80 Future Focal Treatment Approaches to Epilepsy 987Laura Mantoan Ritter and Hannah Cock
81 Epilepsy Surgery in Countries with Limited Resources 999Andre Palmini and Kurupath Radhakrishnan
Index 1008