The Ovary

by Peter C.K. Leung (Editor), Eli Y. Adashi (Editor)

Overview

This second edition of The Ovary incorporates the dramatic research developments regarding the ovarian life cycle within the past decade.
It looks at ovarian function from a detailed molecular and cellular level. The updated chapters, along with the new material, represent an unparalleled compilation of chapters relevant to contemporary ovarian physiology. The book is divided into 8 sections: The Ovarian Follicular Apparatus: Operational Characteristics; Oocyte Maturation and Ovulation; The Corpus Luteum; Putative Intraovarian Regulators; Cyclic Ovarian Cell Death; Novel Experimental Models; Human Ovarian Pathophysiology: Select Aspects; and Human Ovarian Surface Epithelium and Neoplasia.

Product Details

ISBN-13:	9780080542584
Publisher:	Elsevier Science
Publication date:	12/18/2003
Sold by:	Barnes & Noble
Format:	eBook
Pages:	664
File size:	17 MB
Note:	This product may take a few minutes to download.

About the Author

Dr. Leung is a Professor at the University of British Columbia’s Department of Obstetrics & Gynecology and former Associate Dean in the Faculty of Medicine at UBC. Dr. Leung received his PhD from Western University. After post-doctoral training at the University of California at Los Angeles and the Laval University, he joined the University of British Columbia in 1982 as a faculty member. Dr. Leung has received a number of prestigious awards, including a Scholar Award and a Scientist Award from the Medical Research Council of Canada, a Distinguished Scholar Award from the Michael Smith Foundation for Health Research and a Senior Scientist Award from the BC Children Hospital Research Institute. Dr. Leung has served on many national and international organizations, including as President of the Canadian Fertility and Andrology Society, Director of the Society for the Study of Reproduction, Director of the Ovarian Workshops in the USA, temporary advisor to the World Health Organization, Fellow of the Canadian Academy for Health Sciences, and Fellow of the Royal Society of Canada. Dr. Leung’s research focuses on hormonal determinants of women’s reproductive health. His publication record to date includes 400 papers, 350 abstracts, 22 book chapters and 7 monographs. Since his appointment at UBC, Dr. Leung has served as the research supervisor for more than 100 graduate students, postdoctoral fellows and visiting scientists.

Read an Excerpt

Provides the most up-to-date clinical and theoretical information available on ovarian physiology.

Table of Contents

Neural and Neurotrophic Control of Ovarian Development
Dynamics of Human Follicular Growth: Morphologic, Dynamic and Functional Aspects
Dynamics of Primate Follicular Growth: A Physiologic Perspective
Functional Consequences of Mutations and Polymorphisms in Gonadotropin and Gonadotropin Receptor Genes
The Regulation of Gonadotropin Receptor in the Ovary
Prostaglandin Biosynthesis and Action in the Ovary
Actions of Insulin IGF-I on sterol-metabolizing Gene Expression in Ovarian Cells
Intracellular Cholesterol Dynamics in Steroidogenic Cells
Regulation of Mammalian Oocyte Maturation
Oocyte-Granulosa Cell Interactions
Ovulation: An Inflammatory Cascade of Gene Expression
The Function and Regulation of Cell Populations Composing
The Corpus Luteum of the Ovarian Cycle
Luteinization
The Corpus Luteum of Pregnancy
Potential Role of Cytokines in Ovarian Physiology: The Case for Interleukin-1
Activin, Inhibin and Follistatin in Ovarian Physiology
GnRH as an Autocrine Regulator in the Human Ovary
Ovarian Angiogenesis
Apoptosis in Ovarian Development, Function and Failure
Reactive Oxygen Species and Ovarian Function
Follicle Selection in Mammalian Ovaries: Regulatory Mechanisms of Granulosa Cell Apoptosis during Follicular Atresia
Generation and Application of Ovarian Steroidogenic Cell Lines
The Application of Gene Ablation and Related Technologies to the Study of Ovarian Function
Bioinformatic Analysis of Ovarian Genes Using an Ovary-Specific Database
Human Ovarian Pathophysiology: Select Aspects
Gonadotropin Ovulation Induction
The Role of GnRH Antagonists in Supporting Ovarian Hyperstimulation
The Ovarian Factor in Assisted Reproductive Technology
Ovarian Function in Assisted Reproduction
Polycystic Ovary Syndrome
The Role of the Ovary in the Genesis of Hyperandrogenism
Luteal Dysfunction
Germ Cell Failure and Ovarian Resistance: Human Genes and Disorders
Ovarian Function and Survival of Patients with Cervical Carcinoma Treated with Radical Hysterectomy and Ovarian Transposition
Role of Mitochondria in the Aging Ovary
Development & Differentiation of Ovarian Surface Epithelium: Cues for the Basis of its Malignant Potential
Molecular Mechanisms of Ovarian Neoplastic Progression
Ovarian Carcinogenesis
The Role of X-Linked Inhibitor of Apoptosis Protein in Chemoresistant Ovarian Cancer

What People are Saying About This

From the Publisher

Provides the most up-to-date clinical and theoretical information available on ovarian physiology.

Editorial Reviews

"The chapters are well written...The Ovary should be of great value to established scholars in the field because it conveniently reviews the developments of the past decade and will quickly bring them up to date. This handsome volume can be highly recommended. Each chapter is amply referenced, making this book a great resource for anyone with a detailed interest in the ovary." —TRENDS IN ENDOCRINOLOGY AND METABOLISM, SEPTEMBER 2004 "...a comprehensive reference and value for the money...more for those who are curious to enquire into the scientific basis of clinical medicine." —David T. Baird, MB BChr, DSc, Professor Emeritus, University Department of Obstetrics and Gynaecology and Director ofo Contraceptive Development Network, Edinburgh, UK for Journal of Family Planning and Reproductive Health Care, Vol. 31, No. 1 June 20052004

From the Publisher