The Golgi Apparatus: The First 100 Years / Edition 1

by James Morré, Hilton H. Mollenhauer

Overview

The Golgi Apparatus: The First 100 Years traces the first 100 years of Golgi apparatus discovery from the first published accounts from Pavia, Italy in 1898 to the Centenary Celebration in Pavia, Italy in 1998 and into the decade beyond. It is not intended, however, to be a comprehensive survey but rather to present the perspectives of the authors to summarize their contributions over the past 50 years in parallel with the modern era of Golgi apparatus discovery initiated in 1954 and made possible by the advent of the electron microscope. Included are methods of cell fractionation and biochemical analysis leading up to the present where efforts focus heavily on molecular biology. Topics where the authors and their colleagues have made substantial and/or pioneering contributions are emphasized including Golgi apparatus morphology and structural organization and function (especially in plants), the existence and importance of cisternal tubules, development of methods of plant and animal Golgi apparatus isolation and subfractionation, biochemical analyses of highly purified plant and animal Golgi apparatus fractions in comparison to equally highly pu- fied reference fractions.

Product Details

ISBN-13:	9781441925572
Publisher:	Springer New York
Publication date:	10/29/2010
Edition description:	Softcover reprint of hardcover 1st ed. 2009
Pages:	307
Product dimensions:	6.10(w) x 9.25(h) x 0.36(d)

Table of Contents

History of the Golgi Apparatus.- Morphology of the Golgi Apparatus (Architecture/Structure).- Isolation and Subfractionation.- Golgi Apparatus Tubules.- Golgi Apparatus and Membrane Biogenesis.- Golgi Apparatus Function in the Flow-Differentiation of Membranes.- Biochemistry of the Golgi Apparatus.- Golgi Apparatus Function in Secretion.- Golgi Apparatus Replication.- Cell Free Systems for Study of Golgi Apparatus Function.- Golgi Apparatus Function in Growth and Cell Enlargement.- The Golgi Apparatus and Cancer.- The Golgi Apparatus: A Look Ahead.

Editorial Reviews

From the reviews:
“The volume represents a dense personal account of the activities in a very vivid field of biomedical inquiry. … it can provide an important basis for future historical analyses.” (Ariane Dröscher, History and Philosophy of the Life Sciences, Vol. 34 (4), 2012)

From the Publisher