Stacy Richardson is a microbiology graduate student at the University of Southern California, taking her final doctoral exams.**In the middle of her "Quals," Stacy learns that her husband, head of the university's Microbiology Department, has "committed suicide" while on sabbatical at a super-secret bio-weapons lab known as the Devil's Workshop.**
Meanwhile, two train-riding hobos, "Lucky" Cunningham and "Hollywood Mike," are traveling near Vanished Lake, Texas, where the newest generation of bio-weapons is secretly being tested.**A bio-accident at Vanishing Lake turns the town into a living hell; one of the many casualties is Hollywood Mike, who, it turns out, is the son of egomaniacal, larger-than-life motion picture producer Buddy Brazil.
An unlikely trio, Stacy Richardson, Lucky Cunningham, and Buddy Brazil work to expose the horrific truth about the Devil's Workshop while trying to stop a gang of white supremacists from "detonating" the frightening new bio-weapon.