The Cell: A Molecular Approach

by Geoffrey Cooper, Kenneth Adams

Overview

The Cell, outlines the fundamental events related to cell biology and how they impact a wide array of diseases through numerous cell types and mechanisms. New embedded resources including self-assessment, and expanded data analysis problems further facilitate student learning.

Product Details

ISBN-13:	9780197685570
Publisher:	Sinauer Associates is an imprint of Oxford University Press
Publication date:	10/26/2022
Edition description:	9th ed.
Pages:	816
Product dimensions:	11.00(w) x 8.50(h) x 1.50(d)

About the Author

Geoffrey Cooper is a Professor of Biology at Boston University. Receiving a Ph.D. in Biochemistry from the University of Miami in 1973, he pursued postdoctoral work with Howard Temin at the University of Wisconsin, where he developed gene transfer assays to characterize the proviral DNAs of Rous sarcoma virus and related retroviruses. He then joined the faculty of Dana-Farber Cancer Institute at Harvard Medical School in 1975, where he pioneered the discovery of oncogenes in human cancers. He moved to Boston University as Chair of Biology in 1998 and subsequently served as Associate Dean of the Faculty for Natural Sciences, as well as teaching undergraduate cell biology and continuing his research on the roles of oncogenes in the signaling pathways that regulate cell proliferation and programmed cell death. He has authored over 100 research papers, two textbooks on cancer, and an award-winning novel, The Prize, dealing with fraud in medical research.

Table of Contents

PART I: FUNDAMENTALS AND FOUNDATIONS

Chapter 1 Introduction to Cells and Cell Research

Chapter 2 Physical Principles Underlying Cell Structure and Function

Chapter 3 Fundamentals of Molecular Biology

PART II: THE FLOW OF GENETIC INFORMATION

Chapter 4 Genes and Genomes

Chapter 5 Replication, Maintenance, and Rearrangements of Genomic DNA

Chapter 6 RNA Synthesis and Processing

Chapter 7 Transcriptional Regulation and Epigenetics

Chapter 8 Protein Synthesis, Processing, and Regulation

Chapter 9 Genomics, Proteomics, and Systems Biology

PART III: SUB-CELLULAR STRUCTURES AND FUNCTIONS

Chapter 10 The Nucleus

Chapter 11 Protein Sorting and Transport: The Endoplasmic Reticulum, Golgi Apparatus, and Lysosomes

Chapter 12 Mitochondria, Chloroplasts, and Peroxisomes

Chapter 13 The Cytoskeleton and Cell Movement

Chapter 14 The Plasma Membrane

Chapter 15 Cell Walls, the Extracellular Matrix, and Cell Interactions

PART IV: Cell Regulation

Chapter 16 Cell Signaling

Chapter 17 The Cell Cycle

Chapter 18 Cell Renewal and Cell Death

Chapter 19 Cancer

Editorial Reviews

"The new organization is more likely to allow a pick-and-choose approach in which the selection of specific chapters to cover in class is greatly facilitated, as the topics have been separated in a much clearer way. Furthermore, the order in which the different topics will be presented in the updated version follows a much more logical progression. It is true that some basic knowledge is needed before some of the technical aspects can be understood and appreciated. Furthermore, adding more videos and introducing videos that follow a more lecture-like format is a fantastic idea."—German Rosas-Acosta, University of Texas at El Paso

"Addressing basic chemistry, biomolecules, protein structure and function, enzymes, and molecular biology out of the gate is a good idea. The rest of the course builds on these concepts."—Ashok Upadhyaya, University of South Florida

From the Publisher