Synthetic Biodegradable Polymer Scaffolds / Edition 1

by Anthony Atala, David J. Mooney

Overview

This body of work represents the first volume of a book series covering the field of tissue engineering. Tissue engineering, which refers to a category of therapeutic or diagnostic products and processes which are based upon a combination of living cells and biomaterials, was defined as a field only a few years ago (1988). Tissue engineering is an inherently interdisciplinary field, combining bioengineering, life sciences and clinical sciences. The definition of this area of work as the field of tissue engineering brought together scientists from multiple backgrounds who already were working toward the achievement of similar goals. Why a book series exclusively devoted to tissue engineering? The field of tissue engineering is heterogeneous. The cells involved in tissue engineering can be autologous, allogeneic or xenogeneic. The biomaterials utilized can be either naturally occurring, synthetic or a combination of both. The appli­ cation of the technology can be either for acute or permanent purposes. An attempt to cover the field of tissue engineering in a single volume, with the degree of detail necessary for individuals with different scientific backgrounds and disciplines, would be a difficult task to accomplish, particularly when this field is just emerging and changing rapidly. Therefore, addressing different technologies within the field of tissue engineering, in a comprehensive manner, is the main mission of this series of volumes. A stellar group of scientists has been brought together to form the editorial board of the series.

Product Details

ISBN-13:	9780817639198
Publisher:	Birkhäuser Boston
Publication date:	12/01/1997
Series:	Tissue engineering
Edition description:	1997
Pages:	258
Product dimensions:	6.10(w) x 9.25(h) x 0.03(d)

About the Author

Atala, Anthony, MD (Children's Hospital and Harvard Medical School); Mooney, David J., PhD (Univ of Michigan); Vacanti, Joseph P., MD (Children's Hospital, Boston); Langer, Robert, ScD (Massachusetts Institute of Technology)

The contributors represent the specialties of tissue engineering, bioengineering, and bioscience. Most are from U.S. hospitals and universities, including Univ of Massachusetts, Children's Hospital-Boston, Rice Univ, and Georgia Institute of Technology.

Table of Contents

1. The History of Tissue Engineering Using Biodegradable Synthetic Polymer Scaffolds and Cells.- 2. Legal Issues Involved in Tissue Engineering.- 3. FDA Regulation of Tissue Engineering.- Fundamentals of Biodegradable Polymer Scaffolds.- 4. Synthesis and Properties of Biodegradable Polymers used as Synthetic Matrices for Tissue Engineering.- 5. Bioactive Polymers.- Applications.- 6. Drug Delivery Related to Tissue Engineering.- 7. Tissue Engineering in the Epithelial System.- 8. Tissue Engineering in the Genitourinary System.- 9. Tissue Engineering and the Vascular System.- 10. New Frontiers in Tissue Engineering: Tissue Engineered Heart Valves.- 11. Tissue Engineering Cartilage and Bone.- 12. Tissue Engineering of Bone.- 13. Tissue Engineering of the Liver.

Editorial Reviews

Reviews the synthesis and properties of biodegradable polymers used in tissue engineering, and discusses applications for engineering a variety of tissue types, as well as relevant FDA and patent issues. Traces the history of tissue engineering, overviews legal issues, examines properties of synthetic polymers already used in the field and those that could be, and looks at the synthesis of biologically active polymers. Describes how polymers can be used for drug delivery and in engineering epithelial and urologic tissue, vascular structures, cartilage, bone, and liver. Of interest to engineers, scientists, and clinicians. Annotation c. by Book News, Inc., Portland, Or.

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