Solving Problems with NMR Spectroscopy

by Atta-ur Rahman, Muhammad Iqbal Choudhary

Overview

Solving Problems with NMR Spectroscopy presents the basic principles and applications of NMR spectroscopy with only as much math as is necessary. It shows how to solve chemical structures with NMR by giving clear examples and solutions. This text will enable organic chemistry students to choose the most appropriate NMR techniques to solve specific structures. The problems to work and the discussion of their solutions and interpretations will help readers becomeproficient in the application of important, modern 1D and 2D NMR techniques to structural studies.

Key Features
* Presents the most important NMR techniques for structural determinations
* Offers a unique problem-solving approach
* Uses questions and problems, including discussions of their solutions and interpretations, to help readers grasp NMR
* Avoids extensive mathematical formulas
* Forewords by Nobel Prize winner Richard R. Ernst and Lloyd M. Jackman

Product Details

ISBN-13:	9780080541495
Publisher:	Elsevier Science
Publication date:	01/08/1996
Sold by:	Barnes & Noble
Format:	eBook
Pages:	430
File size:	15 MB
Note:	This product may take a few minutes to download.

About the Author

Atta-ur-Rahman, Professor Emeritus, International Center for Chemical and Biological Sciences (H. E. J. Research Institute of Chemistry and Dr. Panjwani Center for Molecular Medicine and Drug Research), University of Karachi, Pakistan, was the Pakistan Federal Minister for Science and Technology (2000-2002), Federal Minister of Education (2002), and Chairman of the Higher Education Commission with the status of a Federal Minister from 2002-2008. He is a Fellow of the Royal Society of London (FRS) and an UNESCO Science Laureate. He is a leading scientist with more than 1283 publications in several fields of organic chemistry.
Muhammad Choudhary, PhD, is a Professor of the International Center for Chemical and Biological Sciences, (H. E. J. Research Institute of Chemistry and Dr. Panjwani Center for Molecular Medicine and Drug Research), University of Karachi, Pakistan. He is a member of the Royal Society of Chemistry, London; American Chemical Society; International Union of Pure and Applied Chemistry (IUPAC); American Society of Pharmacology; New York Academy of Sciences; Federation of Asian Chemical Societies (FACS); and he serves on the executive board of the Asian Network of Research on Anti Diabetic Plants (ANRAP). He is a recipient of the National Book Foundation's Prize for Chemistry and the Economic Cooperation Organization (ECO) Award in Education, 2006, given by the President of Azerbaijan. He has published 24 books, more than 570 papers, and 20 patents.

Table of Contents

The Basics of Modern NMR Spectroscopy:What is NMR? Instrumentation. Creating NMR Signals. Spin-Echo and Polarization Transfer: Spin-Echo Formation in Homonuclear and Heteronuclear Systems. Cross-Polarization. Polarization Transfer in Reverse. The Second Dimension: Data Acquisition in 2D NMR. Data Processing in 2D NMR. Plotting 2D Spectra. Nuclear Overhauser Effect: nOe and Selective Population Transfer. Relaxation. Mechanism of nOe. Factors Affecting nOe. Some Practical Hints. Important 2D NMR Experiments: Homo- and Heteronuclear J-Resolved Spectroscopy. Homonuclear and Heteronuclear Shift-Correlation Spectroscopy. Two-Dimensional Nuclear Overhauser Spectroscopy. Two-Dimensional Chemical Exchange Spectroscopy. Homonuclear Hartmann-Hahn Spectroscopy (HOHAHA), or Total Correlation Spectroscopy (TOCSY). Inverse NMR Spectroscopy. Inadequate. The Third Dimension: Basic Philosophy. Types and Positions of Peaks in 3D Spectra. Recent Developments in NMR Spectroscopy: Selective Pulses in Modern NMR Spectroscopy. One-Dimensional Experiments Using Soft Pulses. Heteronuclear Selective 1D NMR Experiments. Two-Dimensional Experiments Using Soft Pulses. Soft Excitation in Two Dimensions. Three-Dimensional Experiments Using Soft Pulses. Field Gradients. Logical Protocol for Solving Complex Structural Problems: 3-Hydroxylupanine. (1). (+)-Buxalongifolamidine. (2). References. Subject Index.

What People are Saying About This

From the Publisher

Clearly presents the basic principles and applications of NMR spectroscopy and demonstrates how to solve chemical structures with NMR by giving clear examples and solutions

Editorial Reviews

Praise for the First Edition:"Solving Problems with NMR Spectroscopy is a very welcome addition to the existing literature. It fulfills a real need for an up-to-date and authoritatively written introduction for students and practitioners of NMR." —Richard R. Ernest, Nobel Prize in Chemistry, 1991

From the Publisher