Ribosomes / Edition 1

by Alexander S. Spirin

Overview

This text is for advanced undergraduates and beginning graduate studen ts and will cover the structure, function, and biosynthesis of ribosom es. Ribosomes are important in protein synthesis, which is currently a hot topic in many different areas of research.

Product Details

ISBN-13:	9780306461453
Publisher:	Springer US
Publication date:	02/29/2000
Series:	Cellular Organelles
Edition description:	2002
Pages:	416
Product dimensions:	7.01(w) x 10.00(h) x 0.39(d)

Table of Contents

Historical and Fundamental Introduction.- Protein Biosynthesis.- Messenger RNA and the Genetic Code.- Transfer RNA and Aminoacyl-tRNA Synthetases.- Ribosomes and Translation.- Structure of the Ribosome.- Morphology of the Ribosome.- Ribosomal RNA.- Ribosomal Proteins.- Mutual Arrangement of Ribosomal RNA and Proteins (Quaternary Structure).- Function of the Ribosome.- Functional Activities and Functional Sites of the Ribosome.- Elongation Cycle, Step I: Aminoacyl-tRNA Binding.- Elongation Cycle, Step II: Transpeptidation (Peptide Bond Formation).- Elongation Cycle, Step III: Translocation.- Elongation Rates and its Modulation.- Termination of Translation.- Initiation of Translation.- Translational Control in Prokaryotes.- Translational Control in Eukaryotes.- Cotranslational Folding and Transmembrane Transport of Proteins.- Conclusion: General Principles of Ribosome Structure and Function.