Recombinant DNA: Genes and Genomics: A Short Course / Edition 3

by James D. Watson

Overview

The third edition of this landmark text presents a cutting-edge reflection of the new world of genomes and genomics. New coauthors join Nobel laureates James D. Watson and Jan A. Witkowski to offer an authoritative, accessible, and engaging report from front lines of modern scientific inquiry. The authors, drawing on their research expertise, have selected the most relevant and exciting examples of current research -- RNAi, epigenetics, large-scale genomics, cancer, human genetics, and DNA fingerprinting -- and provide the reader with a foundation in the basic principles of genetics and genomics, selecting examples from the past 100 years.

Product Details

ISBN-13:	2900716728664
Publisher:	Freeman, W. H. & Company
Publication date:	12/08/2006
Edition description:	Third Edition
Pages:	474
Product dimensions:	6.00(w) x 1.25(h) x 9.00(d)

About the Author

James D. Watson, co-winner of the Nobel prize for discovering the DNA double helix, is Chancellor of the Cold Spring Harbor Laboratory.

Jan A. Witkowski is Executive Director of the Banbury Center and Professor in the Watson School of Biological Sciences at Cold Spring Harbor Laboratory.

Richard M. Myers is Chairman and Stanford W. Ascherman Professor in the Department of Genetics at Stanford University, and is Director of the Stanford Human Genome Center.

Amy A. Caudy is the Lewis-Stiger Fellow at the Lewis-Stiger Institute for Integrative Genomics at Princeton University.

Table of Contents

FOUNDATIONS OF DNA
1. DNA Is the Primary Genetic Material
2. Information Flow from DNA to Protein
3. Control of Gene Expression
4. Basic Tools of Recombinant DNA
5. Fundamental Features of Eukaryotic Genes
6. A New Toolbox for Recombinant DNA
7. Mobile DNA Sequences in the Genome
8. Epigenetic Modifications of the Genome
9. RNA Interference Regulates the Genome

FOUNDATIONS OF GENOMICS
10. Fundamentals of Whole-Genome Sequencing
11. How the Human Genome was Sequenced

ANALYZING GENOMES
12. Comparing and Analyzing Genomes
13. From Genome Sequence to Gene Function

HUMAN GENOMICS
14. Finding Human Disease Genes
15. Understanding the Genetic Basis of Cancer
16. DNA Fingerprinting and Forensics