WOC nurse specialists and advance practice nurses impact patient care in a variety of health care settings. WOC nurses must demonstrate both clinical expertise and professional practice skills. As clinical experts and leaders, it is essential that WOC nurses perform within the full scope of practice through evidence-based care, education, research, advocacy, and public policy. WOC nursing is multifaceted and requires a wide array of clinical and organizational skills. This fourth edition builds upon previous editions of the Professional Practice Manual as a guidance tool for clinicians, teams, or independent practitioners. The manual is intended to provide a resource and reference that WOC nurses can use in developing, implementing, and expanding their specialty nurse role and practice