Procurement, Preservation and Allocation of Vascularized Organs

by G.M. Collins (Editor), J.-M. Dubernard (Editor), Walter Land (Editor), G. Persijn (Editor)

Overview

This volume includes all procedures and practices relating to the selection of organ donors, removal of organs, preservation and allocation for a successful transplantation. The improving preservation solutions as well as the improving survival rates of transplant patients make it indispensable to have a complete book on all aspects of transplantation. The chapters are divided in four sections: donor conditioning and surgery; organ preservation; allocation and logistics; ethics and legislation in organ donation.
The growing awareness of the need for organ donation and adaptation of laws, as well as the increasing efforts of the transplantation organizations to stimulate organ donation, makes Procurement, Preservation and Allocation of Vascularized Organs a very timely publication.
This is the first complete book on the topic and is aimed at medical specialists in any hospital involved, or potentially involved, in organ procurement, transplant coordinators and administrators, transplant surgeons, nephrologists and other organ specialists and researchers.
The chapters on surgical techniques are illustrated with original artwork by Bernard Tardieu.

Product Details

ISBN-13:	9780792342991
Publisher:	Springer-Verlag New York, LLC
Publication date:	11/28/1997
Edition description:	New Edition
Pages:	384
Product dimensions:	8.00(w) x 10.00(h) x 0.88(d)

About the Author

Collins, G.M. (California Pacific Medical Center); Dubernard, J.M. (Hopital Edouard Herriot, Lyon); Land, W. (Univ of Munich); Persijn, G.G. (Eurotransplant Foundation, Leiden)

Table of Contents

Section I: Donor Conditioning and Surgery.- 1 Living kidney donation: preoperative evaluation and preparation for surgery.- 2 Kidney recovery from living related donors.- 3 Anaesthesia and resuscitation of the genetically related living donor in liver transplantation.- 4 Living-related liver transplantation (LRLT).- 5 Diagnosis of brain death.- 6 Selection of multivisceral cadaveric organ donors.- 7 Management of the cadaver donor in the intensive care unit.- 8 Donor conditioning in organ procurement.- 9 Perioperative management of cadaveric donor.- 10 Multiple organ procurement.- 11 The contribution of the non-heart-beating donor to the solution of the shortage of kidneys.- Section II: Organ Preservation.- 12 Biochemistry and cell physiology of organ preservation.- 13 Preservation by simple hypothermia.- 14 Pulsatile preservation in renal transplantation.- 15 Endothelial cell damage and Kupffer cell activation in reperfusion injury to livers stored for transplantation.- 16 Pharmacological agents in organ preservation.- 17 Kidney preservation.- 18 Liver preservation: historical review of preservation techniques.- 19 Heart and lung preservation.- 20 Small bowel preservation.- 21 Pancreas preservation.- Section III: Allocation and Logistics.- 22 Principles of kidney allocation.- 23 Principles of liver allocation in Eurotransplant.- 24 Principles of heart allocation.- 25 Kidney allocation in highly sensitized patients.- 26 Principles of lung allocation.- 27 Organization and logistics in organ exchange.- 28 Costs of transplantation.- 29 The role of the transplant coordinator.- 30 Organ availability in Europe: problems and results.- 31 Donor hospital development in non-university hospitals.- 32 Kidney preservation and graft outcome: Eurotransplant experience.- 33 Primary dysfunction after orthotopic liver transplantation.- 34 Results of intestinal transplantation.- 35 Cardiac transplant survival in relation to preservation.- Section IV: Ethics and Legislation in Organ Donation.- 36 Voluntarism and coercion in living organ donation.- 37 Reimbursement, ‘rewarded gifting’, financial incentives and commercialism in living organ donation.- 38 International legislation in living organ donation.- 39 Psychological aspects in living organ donation.- 40 Brain death.- 41 A survey of religious attitudes towards organ donation and transplantation.- 42 Philosophical arguments for accepting the brain death criterion.- 43 Legal and judicial aspects of postmortem organ donation.- 44 The dilemma of organ allocation: the combination of a therapeutic modality for an ill individual with the distribution of a scarce valuable public (health) good.- 45 Living unrelated kidney transplantation.

Editorial Reviews

Reviewer: Bryan F. Meyers, MD (Washington University School of Medicine)
Description: This book is a multi-authored examination of the important work and decision-making which make organ transplantation possible. The 45 chapters of this book are divided into 4 sections covering donor conditioning and surgery, organ preservation, allocation and logistics, and ethics and legislation.
Purpose: The authors have managed to collect an impressive array of international and multidisciplinary experts in transplantation to address the key issues in achieving and protecting a safe supply of organs for transplantation.
Audience: The expected audience includes surgical and medical transplant physicians, transplant coordinators, and students.
Features: The international perspective offered in this work is particularly useful as it addresses topics with heavy cultural associations: living related organ donations; compensated living donors; and the variable definitions of brain death. The book may lack some currency when carefully inspected by practitioners within a narrow subspecialty. For example, the entire topic of heart and lung preservation was condensed into less than three pages and lacked any references more recent than 1993. The review included no mention of the "marginal donor," living-related lobar donors, the use of nitroprusside or nitric oxide in the donor, or other topics of recent importance in lung preservation and procurement. Chapters are included which describe the results of kidney, liver, intestinal, and heart transplants with an emphasis on the impact of graft preservation in the observed outcome.
Assessment: This book represents a unique approach offering viewpoints that cross national and subspecialty boundaries. This is a worthwhile reference which would be a fitting addition to a departmental library. Non-medical personnel with an interest in the legal and ethical considerations surrounding organ donation will find the final section interesting and informative. Specialists interested in current details pertaining to the preservation and use of specific organs will be better served with recent review articles in specialty journals.

Doody's Review Service

3 Stars from Doody

This book is a multi-authored examination of the important work and decision-making which make organ transplantation possible. The 45 chapters of this book are divided into 4 sections covering donor conditioning and surgery, organ preservation, allocation and logistics, and ethics and legislation. The authors have managed to collect an impressive array of international and multidisciplinary experts in transplantation to address the key issues in achieving and protecting a safe supply of organs for transplantation. The expected audience includes surgical and medical transplant physicians, transplant coordinators, and students. The international perspective offered in this work is particularly useful as it addresses topics with heavy cultural associations: living related organ donations; compensated living donors; and the variable definitions of brain death. The book may lack some currency when carefully inspected by practitioners within a narrow subspecialty. For example, the entire topic of heart and lung preservation was condensed into less than three pages and lacked any references more recent than 1993. The review included no mention of the ""marginal donor,"" living-related lobar donors, the use of nitroprusside or nitric oxide in the donor, or other topics of recent importance in lung preservation and procurement. Chapters are included which describe the results of kidney, liver, intestinal, and heart transplants with an emphasis on the impact of graft preservation in the observed outcome. This book represents a unique approach offering viewpoints that cross national and subspecialty boundaries. This is a worthwhile reference which would be a fitting addition to a departmentallibrary. Non-medical personnel with an interest in the legal and ethical considerations surrounding organ donation will find the final section interesting and informative. Specialists interested in current details pertaining to the preservation and use of specific organs will be better served with recent review articles in specialty journals.

Bryan F. Meyers