Prions and Mad Cow Disease

Prions and Mad Cow Disease

Prions and Mad Cow Disease

Prions and Mad Cow Disease

eBook

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Overview

The alarm sounded by Canada's confirmed case of bovine spongiform encephalopathy (BSE) has reaffirmed the exigency of establishing improved safeguards and more aggressive surveillance protocols in North America and around the world. Research converging on the probable causative agent--prion proteins--calls for intensive assessment of the headway gained in tracing prions, testing for transmissible neurodegenerative diseases, and developing methods for cornering the epidemic. With an illustrious panel of 36 international contributors, this timely book marshals techniques for prion protein assay and diagnosis of transmissible spongiform encephalopathies (TSEs).

Product Details

ISBN-13: 9781135525781
Publisher: CRC Press
Publication date: 10/17/2003
Sold by: Barnes & Noble
Format: eBook
Pages: 413
File size: 6 MB

About the Author

Brian K. Nunnally and Ira S. Krull

Table of Contents

Foreword, Preface, Contributors, 1. Taking Aim at the Transmissible Spongiform Encephalopathies Infectious Agents, 2. Prions, the Protein Hypothesis, and Scientific Revolutions, 3. A Simulation Model for Evaluating the Potential for Spread of Bovine Spongiform Encephalopathy in Animals or to People, 4. Actions to Prevent Bovine Spongiform Encephalopathy from Entering the United States, 5. Overview of Transmissible Spongiform Encephalopathy in Cervids in the United States, 6. Bioassays for Prions, 7. Cyclic Amplification of Scrapie Prion Protein: Implications for Diagnosis, 8. The Enfer Transmissible Spongiform Encephalopathies Assay: Chemiluminescent ELISA of Prion Proteins, 9. Sensitive Detection of Prion Proteins by Immunoassay: CEA/Bio-Rad Test, 10. The Diagnosis of Transmissible Spongiform Encephalopathies Using Differential Extraction and DELFIA, 11. In Vivo Diagnosis of Prion Diseases, 12. Diagnosis of Prion Diseases by Multispectral Techniques, 13. Detection of the Prion Protein in Blood Using a Fluorescence Immunoassay, 14. Prion Detection and Application to the Safety of Biological Products, Index
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