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Primer on the Autonomic Nervous System
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Primer on the Autonomic Nervous System
882Paperback(4th ed.)
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Overview
Product Details
ISBN-13: | 9780323854924 |
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Publisher: | Elsevier Science |
Publication date: | 12/09/2022 |
Edition description: | 4th ed. |
Pages: | 882 |
Product dimensions: | 8.50(w) x 10.88(h) x (d) |
About the Author
Dr. Kirsteen Browning is a Professor of Neural and Behavioral Science at Penn State University. She is also Associate Director of the MD/PhD Medical Scientist Training Program. Her research interest is in the regulation of gastrointestinal vagal neurocircuits and vagally mediated peripheral sensation and signaling.
Dr. Gregory Fink is a Professor in Pharmacology and Toxicology at Michigan State University. His research continues to concern central and peripheral mechanisms of blood pressure regulation in hypertension, but other important interests are the renin-angiotensin system, endothelin and the role of venous function and body fluid volume distribution in control of blood pressure. Fink has served on the executive committee and as treasurer for the Inter-American Society of Hypertension, as chairman of the National Institutes of Health, or NIH , Experimental Cardiovascular Sciences Study Section and he just recently finished a two-year term as chair of the American Heart Association Council on Hypertension.
Jens Jordan is Head of the Institute of Aerospace Medicine at the German Aerospace Center and the University of Cologne in Germany. Previously, he directed the Institute for Clinical pharmacology at Hannover Medical School. His group pursues cardiovascular control mechanisms and molecular mechanisms responsible for premature cardiovascular and metabolic disease in human beings. The overall goal is to find ways of extending the healthy lifespan on earth and in space.
Dr. Phillip Low is a Neurologist at the Mayo Clinic focusing on Autonomic Disorders. Phillip A. Low, M.D. has a long-standing research focus on clinical and laboratory research into the cause and treatment of autonomic disorders. Efforts have been concentrated on following major areas: multiple system atrophy; development of novel biomarkers and tests and instruments to study autonomic disorders; diagnosis and treatment of autonomic neuropathies; conducting randomized clinical trials. Dr. Low's research has been continuously funded by the National Institutes of Health (NIH) for over the past 30 years.
Professor Paton is the Director of Manaaki Manawa – the Centre for Heart Research in Auckland. Through modulation of the autonomic nervous system, his research aims to inform new potential ways to control blood pressure in the condition of hypertension and to alleviate heart failure and sleep apnoea. He uses an inter-disciplinary approach involving mathematical modelling, pre-clinical and first-in-human studies incorporating novel drugs and device based therapeutic strategies.
Table of Contents
Contributors xi
Preface xix
Acknowledgments xxi
I Introduction
1 Evolution of the cardiovascular autonomic nervous system in vertebrates Tobias Wang Renato Filogonio William Joyce 3
2 Central autonomic control Kamal Shouman Eduardo E. Benarroch 11
3 Peripheral autonomic nervous system Waqar Waheed Margaret A. Vizzard 17
II Biochemical and pharmacological mechanisms
4 Noradrenergic neurotransmission David S. Goldstein 33
5 Antidepressant-sensitive norepinephrine transporters: structure and regulation Maureen K. Hahn 39
6 α1-Adrenergic receptors Xenia Kaidonis Marion C. Mohl Robert M. Graham 43
7 Alpha2-adrenergic receptors Eduardo Listik Qin Wang 49
8 β-Adrenergic receptors Vsevolod V. Gurevich 53
9 Dopaminergic neurotransmission Graeme Eisenhofer Timo Siepmann Heinz Reichmann 57
10 Dopamine receptors Sean M. Peterson Nikhil Urs Marc G. Caron 63
11 Cholinergic neurotransmission Brett A. English Carrie K. Jones 67
12 Acetylcholine and muscarinic receptors Katharina Brandl Nora Laiken 73
13 Nicotinic acetylcholine receptors in the autonomic nervous system Ursula H. Winzer-Serhan 77
14 Neuropeptide Y and the autonomic nervous system Calum Robertson David J. Paterson Neil Herring 81
15 Serotonin receptors Charles D. Nichols 89
16 Purinergic neurotransmission and nucleotide receptors Samuel J. Fountain 93
17 Nitric oxide and the autonomic nervous system Alfredo Gamboa 99
18 Glutamatergic neurotransmission Deborah Bauer Michael B. Robinson 103
19 Pharmacology: GABAergic neurotransmission Kirill A. Zavalin Andre H. Lagrange 109
20 Renin-angiotensin Amy C. Arnold Debra I. Diz 113
21 Aldosterone, the mineralocorticoid receptor, and sympathetic nervous system Elise P. Gomez-Sanchez Celso E. Gomez-Sanchez 119
22 Vasopressin in central autonomic regulation Soledad Barez-Lopez David Murphy Nina Japundzic-Zigon 123
23 Calcitonin gene-related peptide and adrenomedullin Ambrish Kumar Jay D. Potts Donald J. Dipette 129
24 Leptin signaling and energy homeostasis Michael M. Scott Kevin W. Williams 135
25 The endothelin system Nathanne S. Ferreira Ernesto L. Schiffrin 141
26 Pharmacology of the neurotransmission of the baro- and chemoreflex in the Nucleus Tractus Solitarius David D. Kline Benedito H. Machado Daniela Accorsi-Mendonça 147
III Autonomic physiology
27 Rhythms in sympathetic nerve activity Susan M. Barman 157
28 Circadian rhythms and autonomic function Diego A. Golombék Daniel E. Vigo 161
29 Cardiorespiratory interactions in health and disease Daniel B. Zoccal Benedito H. Machado Davi J.A. Moraes 165
30 Baroreceptor reflexes Mark W. Chapleau 171
31 Cardiac and other visceral afferents Han-Jun Wang Joseph Hadaya Jeffrey L. Ardell 179
32 Sympathetic control of the heart Jakub Tomek Neil Herring David J. Paterson 185
33 Cardiac vagal ganglia David J. Adams Jesse L. Ashton Johanna M. Montgomery 193
34 Physiology of the upright posture Wouter Wieleng Victoria E. Claydon 199
35 Cerebral circulation Ronald Schondorf 203
36 Autonomic control of the pupil Karen M. Joos Reid Longmuir 209
37 Gastrointestinal function Michael Camilleri 213
38 Extrinsic control of gastrointestinal function Kirsteen N. Browning R. Alberto Travagli 219
39 The splanchnic circulation Gregory D. Fink John W. Osborn 223
40 Autonomic control of the kidney Edwin Kerry Jackson 227
41 Autonomic control of the lower urinary tract Takeya Kitta Naoki Yoshimura 235
42 Bladder function in health and disease Marcus J. Drake Brian A. Parsons 241
43 Physiology and pathophysiology of female sexual function Max J. Hilz Ruihao Wang 247
44 Regulation of sweating Elizabeth A. Coon Phillip A. Low 253
45 Autonomic innervation of the skeleton Florent Elefteriou Preston J. Campbell Maria-Bernadette Madel 257
46 Regulation of metabolism by the autonomic nervous system Christopher Bell 263
47 Sex differences in autonomic function Qi Fu 267
48 Autonomic control during pregnancy Virginia L. Brooks 273
49 Aging and the autonomic nervous system Ralf Habermann Italo Biaggioni 279
50 Autonomic function in sleep and sleep deprivation Ian M. Greenlund Jason R. Carter 283
51 Telemetric autonomic monitoring Carolyn J. Barrett Sarah-Jane Guild Fiona D. McBryde 287
IV Autonomic response to environmental challenges
52 Exercise Meredith Bryarly Qi Fu Benjamin D. Levine 295
53 Psychological stress and the autonomic nervous system Viktor Oubaid 301
54 Hypoglycemia Italo Biaggioni 305
55 Autonomic response to hypovolemic shock Victor A. Convertino Natalie J. Koons 309
56 Physiology of thermoregulation; central and peripheral mechanisms Nisha Charkoudian Shaun F. Morrison 315
57 Effects of high altitude Ulrich Limper 323
58 Space physiology Gilles Clément Scott Wood 329
59 Noise, air pollution, and the autonomic nervous system Jens Jordan Eva-Maria Elmenhorst 333
V Pathophysiological mechanisms
60 The autonomic inflammatory reflex Robin M. McAllen Michael J. McKinley Davide Martelli 341
61 Reactive oxygen species and oxidative stress Rhian M. Touyz Livia L. Camargo 345
62 Insulin resistance and the autonomic nervous system Alfredo Gamboa Italo Biaggioni Elisabeth Lambert 353
63 Salt sensitivity of blood pressure Cheryl L. Laffer Fernando Elijovich 357
64 Airway afferent nerves Joyce S. Kim Bradley J. Undem 367
VI Evaluation of autonomic function
65 Clinical evaluation of autonomic disorders Paola Sandroni 375
66 Autonomic function testing Wolfgang Singer Phillip A. Low 379
67 Tilt table testing Brennan A. Ballantyne Satish R. Raj 385
68 Patient symptom and rating scales: OHQ, COMPASS, UMSARS Wolfgang Singer 391
69 Sympathetic microneurography and clinical applications Vaughan G. Macefield 395
70 Assessment of the autonomic control of the cardiovascular system by a frequency domain approach Andre Diedrich Raffaello Furlan 403
71 Evaluation of sudomotor function Elizabeth A. Coon 409
72 Plasma catechols David S. Goldstein 415
73 Imaging cortical and subcortical sites involved in cardiovascular control Vaughan G. Macefield Luke A. Henderson 421
74 Clinical sympathetic neuroimaging Guillaume Lamotte David S. Goldstein 427
75 Cutaneous autonomic innervation: assessment by skin biopsy Christopher H. Gibbons 433
76 Sympatho-effector transduction James P. Fisher Lauro C. Vianna Paul J. Fadel 439
VII Cardiovascular disorders
77 Neurally mediated syncope (Autonomically mediated syncope) Brennan A. Ballantyne Satish R. Raj 447
78 Otthostatic hypotension Italo Biaggioni 453
79 Spectrum of orthostatic hypotension Wolfgang Singer Phillip A. Low 457
80 Baroreflex failure Jens Jordan 461
81 Essential hypertension Gino Seravalle Guido Grassi 467
82 Obesity-associated hypertension Alfredo Gamboa Luis E. Okamoto Cyndya A. Shibao Italo Biaggioni 471
83 Pheochromocytoma and paraganglioma Christina Pamporaki Jacques W.M. Lenders Graeme Eisenhofer 475
84 Autonomic dysfunction in heart failure Mark B. Badrov John S. Floras 483
85 Myocardial stunning and takotsubo cardiomyopathy Lucy Norcliffe-Kaufmann 489
86 The autonomic nervous system and cardiac arrhythmias Aadhavi Sridharan Peter Hanna Kalyanam Shivkumar 495
VIII Congenital autonomic disorders
87 Deficiencies of tetrahydrobiopterin, tyrosine hydroxylase, and aromatic L-amino acid decarboxylase Keith Hyland Lauren A. Hyland 503
88 Congenital disorders of noradrenergic neurotransmission Italo Biaggioni Emily M. Garland Cyndya A. Shibao 507
89 Monoamine oxidase deficiency Jacques W.M. Lenders Graeme Eisenhofer 513
90 Congenital central hypoventilation syndrome (CCHS) and PHOX2B pathogenic variants Debra E. Weese-Mayer Casey M. Rand Kai Lee Yap 515
91 Hereditary autonomic neuropathies Kamal Shouman 521
92 Familial dysautonomia (Riley-Day syndrome) Lucy Norcliffe-Kaufmann Horacio Kaufmann 527
IX Autonomic synucleinopathies
93 α-Synuclein and neurodegeneration Nadia Stefanova 535
94 Multiple system atrophy Guillaume Lamotte Elizabeth A. Coon 539
95 Parkinson disease John Y. Fang 549
96 Dementia with Lewy bodies Fabian Leys Alessandra Fanciulli Gregor K. Wenning 553
97 Pure autonomic failure Horacio Kaufmann David S. Goldstein 559
X Peripheral autonomic disorders
98 Small fiber neuropathy Amanda C. Peltier 565
99 Diabetic autonomic dysfunction Amanda C. Peltier Stephen N. Davis 569
100 Amyloidosis and autonomic failure Pitcha Chompoopong Michelle L. Mauermann 575
101 Autoimmune autonomic syndromes Steven Vernino Phillip A. Low 585
102 Paraneoplastic autonomic dysfunction Andrew McKeon Jennifer A. Tracy 591
103 Autonomic disturbances following spinal cord injury Christopher J. Mathias David A. Low Victoria E. Claydon 599
104 Drug-induced autonomic dysfunction Amr Wahba James M. Luther 607
XI Autonomic syndromes
105 Postural tachycardia syndrome. Pathophysiological mechanisms Italo Biaggioni Julian Stewart 613
106 Postural tachycardia syndrome (POTS) Guillaume Lamotte Phillip A. Low 619
07 Joint hypermobility and dysautonomia Mohammed Ruzieh Blair P. Grubb 623
108 Mast cell activation and autonomic disorders John M. Fahrenholz, II Cyndya A. Shibao 627
109 Chronic fatigue syndrome and the autonomic nervous system Lauren E. Stiles Luis E. Okamoto 631
XII Special clinical conditions
110 Neuroleptic malignant syndrome Amy E. Brown Andrew Giritharan Fenna T. Phibbs 637
111 Migraine and autonomic nervous system Pietro Cortelli Umberto Pensato Giulia Pierangeli 641
112 Autonomic regulation in epilepsy Dmitry Zhuravlev Alla Guekht Max J. Hilz 645
113 Autonomic complications of acute brain injury and stroke Alejandro A. Rabinstein 651
114 Sleep apnea Thomas Konecny Virend Somers 657
115 Panic disorder: Autonomic nervous mechanisms of risk Murray Esler Gavin Lambert David Kaye Elisabeth Lambert Rosemary Esler Ling Guo Marlies Alvarenga 663
116 Disorders of sweating Elizabeth A. Coon Robert D. Fealey 671
117 Complex regional pain syndrome Wilfrid Jänig 679
118 Abdominal pain and cyclic vomiting Gisela Chelimsky Thomas C. Chelimsky 685
119 Male erectile dysfunction Douglas F. Milam 691
XIII Management of neurogenic orthostatic hypotension
120 Management of orthostatic hypotension, Introduction Italo Biaggioni 699
121 Physical measures Wouter Wieling Roland D. Thijs 705
122 Dietary sodium and fludrocortisone Cyndya A. Shibao Italo Biaggioni Rose Marie Robertson 709
123 Water and the osmopressor response Jens Jordan 713
124 Midodrine Jose-Alberto Palma Horacio Kaufmann 717
125 Droxidopa Jose-Alberto Palma Horacio Kaufmann 721
126 Pyridostigmine in autonomic disorders Guillaume Lamotte Phillip A. Low Wolfgang Singer 729
127 Norepinephrine transporter inhibitors in autonomic disorders Cyndya A. Shibao 733
128 Acarbose and octreotide for the treatment of postprandial hypotension Cyndya A. Shibao 737
129 Management of supine hypertension in patients with autonomic failure Luis E. Okamoto Italo Biaggioni 741
130 Anesthetic considerations in patients with autonomic dysfunction John R. Shannon 747
131 Chronic constitutional hypotension Giris Jacob Raffaello Furlan 753
XIV Autonomic neuromodulation as a treatment strategy
132 Renal denervation as therapeutic intervention Murray Esler Gavin Lambert Elisabeth Lambert Ling Guo Markus Schlaich 759
133 Baroreflex amplification by carotid sinus stimulation Jens Jordan Jens Tank 767
134 Targeting carotid body chemoreceptors as a therapeutic intervention Emma N. Bardsley Harold D. Schultz Piotr Niewinski Julian F.R. Paton 771
135 Bionic baroreflex Takayuki Sato André Diedrich Kenji Sunagawa 779
136 Therapeutic targeting of splanchnic nerves Abu Baker Sheikh Abdul Mannan Khan Minhas Marat Fudim 785
XV Novel approaches in autonomic neuroscience
137 Modeling the autonomic nervous system Alona Ben-Tal 795
138 Optogenetics: application to central autonomic regulatory pathways Andrew M. Allen Clément Menuet 801
139 Mapping the autonomic nervous system: the SPARC project Mahyar Osanlouy Mabelle Lin Ellas Soltani Peter Hunter 807
140 Autonomic nervous system-gut-microbiome axis in chronic diseases Jasenka Zubcevic Mohan K. Raizada 815
141 Novel fluid biomarkers in synucleinopathies Wolfgang Singer Phillip A. Low 821
142 Novel disease-modifying treatments for synucleinopathies Wolfgang Singer Jose-Alberto Palma Horacio Kaufmann Phillip A. Low 825
Index 831
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Concise and accessible overview of autonomic neuroscience for students, scientists and clinicians