Primer on Cerebrovascular Diseases

by Louis R. Caplan (Editor), Jose Biller (Editor), Megan C. Leary (Editor), Eng H. Lo PhD (Editor), Ajith J Thomas (Editor)

Overview

Primer on Cerebrovascular Diseases, Second Edition, is a handy reference source for scientists, students, and physicians needing reliable, up-to-date information on basic mechanisms, physiology, pathophysiology, and medical issues related to brain vasculature. The book consists of short, specific chapters written by international experts on cerebral vasculature, presenting the information in a comprehensive and easily accessible manner.

Numerous changes have occurred in the field since the publication of the first edition in 1997, particularly our understanding of the genetic aspects of cerebrovascular disease. This updated edition reflects the advances made over the last two decades, not only demonstrating the promise for therapy, but also for a molecular understanding of cerebrovascular diseases. The new edition includes new and expanded topics, including carotid stenting, Iatrogenic causes of stroke, axonal transport and injury, RNAIs, proteomics, and more.

2018 BMA Medical Book Awards Highly Commended in Neurology.

• Provides concise chapters on topics in cerebral blood flow and metabolism, pathogenesis of cerebrovascular disorders, diagnostic testing, and management in a comprehensive and accessible format
• Written by international leading authorities on cerebral vasculature
• Provides up-to-date information on practical applications of basic research and the main clinical issues facing the community, such as axonal transport and proteomics

Product Details

ISBN-13:	9780128030592
Publisher:	Elsevier Science
Publication date:	02/10/2017
Sold by:	Barnes & Noble
Format:	eBook
Pages:	968
File size:	50 MB
Note:	This product may take a few minutes to download.

About the Author

Louis R. Caplan, M.D. (Editor)

Beth Israel Deaconess Medical Center, Harvard University, Boston, MA

Dr. Caplan is a world-renowned neuroscientist and a senior member of the Division of Cerebrovascular Disease at Beth Israel Deaconess Medical Center, Boston. He is a Professor of Neurology at Harvard Medical School, Boston, and the founder of the Harvard Stroke Registry. Dr. Caplan is the author or editor of 45 books and more than 700 articles in medical journals. He is a member of many professional societies, serving as an officer on committees for the American Heart Association, the American Academy of Neurology, and the American Neurological Association. He has served as the Chair of both the Boston Society of Neurology and the Chicago Neurological Society.
José Biller, M.D., FACP, FAAN, FANA, FAHA

Loyola University Chicago, Maywood, IL, USA

Dr. José Biller is Professor of Neurology and Neurological Surgery and Chairperson of the Department of Neurology at Loyola University Chicago Stritch School of Medicine. Dr. Biller served as Director of the American Board of Psychiatry and Neurology (ABPN) from 1994 to 2001, and President of the ABPN in 2001. He is Chief Editor of the Journal of Stroke and Cerebrovascular Diseases , and an editorial board member and reviewer for an array of other national and international journals and publications. He is a Fellow of the American Academy of Neurology, American Neurological Association, American College of Physicians, and the Stroke Council of the American Heart Association. He has published more than 370 peer-reviewed articles, more than 150 book chapters, and numerous books.
Megan Carroll Leary, M.D. (Editor)

Department of Neurology, Lehigh Valley Hospital and Health Network, Allentown, PA USA

Dr. Leary is a neurologist with 15 years clinical experience, who specializes in Neurology and Vascular Neurology. She currently is the Neurology Residency Program Director for Lehigh Valley Hospital and Health Network in Allentown, PA, and is an Assistant Professor of Neurology in affiliation with Morsani College of Medicine at the University of South Florida. Dr. Leary is also a consulting neurologist at Harvard Clinical Research Institute at Harvard Medical School. Additionally, Dr. Leary is a member of many professional societies and serves on the American Board of Psychiatry and Neurology's Vascular Neurology Examination Committee. Her interests include cryptogenic stroke, acute ischemic stroke, and the association between cardiac disease and stroke.
Eng H. Lo is a basic neurovascular scientist. He helped develop the neurovascular unit concept (Lo, Nat Rev Neurosci 2003; Tiedt et al, Nat Rev Neurol 2022).
Ajith J. Thomas, M.D.

Beth Israel Deaconess Medical Center, Harvard University, Boston, MA

Dr. Thomas is a Neurosurgeon Co- Director of the Brain Aneurysm Institute at Beth Israel Deaconess Medical Center. He is also an Assistant Professor of Neurosurgery at Harvard University Medical School. He is the Program director for the Cerebrovascular fellowship for cranial and endovascular neurosurgery and site director for the Beth Israel Deaconess Center Neurosurgery Residency program. He has authored more than 100 peer reviewed papers in neurosurgery and several book chapters. His clinical interests are Subarachnoid Hemorrhage; Aneurysms; Stroke; Arteriovenous Malformations; Trigeminal Neuralgia; Peripheral Nerve Disorders. He is board certified from the American Board of Neurological Surgery.
Midori A. Yenari, M.D.

University of California, San Francisco, San Francisco, CA

Dr. Yenari specializes in vascular neurology, and is on the faculty in the Department of Neurology at the University of California, San Francisco. She is also a staff neurologist and stroke program director at the San Francisco Veterans Affairs Medical Center. Her research focuses on the cellular and molecular mechanisms of stroke and potential therapies particularly as they pertain to immune modulation and therapeutic hypothermia. Dr. Yenari is a fellow of the American Academy of Neurology, a fellow of the American Heart Association and has served on editorial boards for Stroke, Journal of Cerebral Blood Flow and Metabolism, Neurobiology of Disease and Translational Stroke Research.
John H. Zhang, M.D., Ph.D. (Editor)

Loma Linda University Medical School, Loma Linda, CA

Dr. Zhang is currently Professor of Anesthesiology, Neurosurgery, Neurology, Basic Sciences (Physiology&Pharmacology), Pathology&Human Anatomy, and Nursing at Loma Linda University Medical Center. He also serves as Director of Center for Brain Hemorrhage Research, Vice-Chair, Department of Basic Sciences (Chief of Division of Physiology) and Director of Physiology Graduate Training Program, Director of Basic Science Research Division in Neurosurgery and Anesthesiology. Dr. Zhang’s research efforts have been supported by grants from American Heart Association, National Institute of Health, and Department of Defense as well as other Regional foundations and Industry with more than 23 million US dollars. Dr. Zhang has published more than 600 peer reviewed articles and has been invited to speak in meetings, seminars, and grand rounds more than 300 times.

Table of Contents

PART I. BASIC CHAPTERSSection 1. Anatomy and PhysiologySection 2. PathophysiologySection 3. NeuroprotectionSection 4. Molecular MechanismsSection 5. Models and Methods

PART II. CLINICAL CHAPTERSSection 6. Clinical Aspects: Medical and SurgicalSection 7. Medical Conditions and StrokeSection 8. Diagnostic TestingSection 9. Management

What People are Saying About This

From the Publisher

Handy reference on cerebral blood flow and metabolism, pathogenesis and pathology, medical conditions, diagnostic testing, and management of cerebrovascular diseases

Editorial Reviews

4 Stars! from Doody

This comprehensive, well-edited, up-to-date book covers all aspects of the basic and clinical study of stroke through focused articles by more than 200 authorities. "The purpose is to provide the serious student of stroke with a current, comprehensive, educational resource. Given the profound advances in the basic and clinical science of stroke, this is a welcome addition. "The audience includes the serious student involved in stroke research, housestaff, fellows, and clinicians, particularly neurologists and neurosurgeons with subspecialty interests in stroke, and to a lesser degree primary care providers. The editors are outstanding figures in modern stroke science. "This is an extremely comprehensive, high-quality primer composed of numerous short, well-edited, informative chapters written by notable authorities. Four basic sections cover cerebral blood flow, pathogenesis and pathology, medical and surgical aspects, and investigation and management. References are select, and the book is amply illustrated. A more extensive index, however, would have been appreciated. "This is a high-quality text. The interested reader will find it extremely useful as a reference and as a didactic volume. Libraries, bookstores, and individuals should purchase it. I expect it will lend itself nicely to subsequent editions. I strongly recommend it.

Steven U. Brint

"The editors are outstanding figures in modern stroke science. This is an extremely comprehensive, high-quality primer composed of numerous short, well-edited, informative chapters written by notable authorities." —Steven U. Brint, MD, University of Illinois at Chicago College of Medicine, for DOODY'S PUBLISHING REVIEWS

From the Publisher

Reviewer: Steven U. Brint, MD (University of Illinois at Chicago College of Medicine)
Description: This comprehensive, well-edited, up-to-date book covers all aspects of the basic and clinical study of stroke through focused articles by more than 200 authorities.
Purpose: The purpose is to provide the serious student of stroke with a current, comprehensive, educational resource. Given the profound advances in the basic and clinical science of stroke, this is a welcome addition.
Audience: The audience includes the serious student involved in stroke research, housestaff, fellows, and clinicians, particularly neurologists and neurosurgeons with subspecialty interests in stroke, and to a lesser degree primary care providers. The editors are outstanding figures in modern stroke science.
Features: This is an extremely comprehensive, high-quality primer composed of numerous short, well-edited, informative chapters written by notable authorities. Four basic sections cover cerebral blood flow, pathogenesis and pathology, medical and surgical aspects, and investigation and management. References are select, and the book is amply illustrated. A more extensive index, however, would have been appreciated.
Assessment: This is a high-quality text. The interested reader will find it extremely useful as a reference and as a didactic volume. Libraries, bookstores, and individuals should purchase it. I expect it will lend itself nicely to subsequent editions. I strongly recommend it.

Doody's Review Service