Pharmaceutical Dosage Forms: Capsules

by Larry L. Augsburger (Editor), Stephen W. Hoag (Editor)

Overview

Pharmaceutical Dosage Forms: Capsules covers the development, composition, and manufacture of capsules. Despite the important role that capsules play in drug delivery and product development, few comprehensive texts on the science and technology of capsules have been available for the research and academic environments. This text addresses this gap, discussing how capsules provide unique capabilities and options for dosage form design and formulation.

Product Details

ISBN-13:	9781351620390
Publisher:	CRC Press
Publication date:	10/30/2017
Sold by:	Barnes & Noble
Format:	eBook
Pages:	435
File size:	6 MB

About the Author

Larry Augsburger is an Emeritus Professor at the University of Maryland School of Pharmacy.

Stephen W. Hoag, Ph.D., is a Professor of Pharmaceutical Sciences at the University of Maryland, Baltimore.

Table of Contents

1. Advances in Capsule Formulation Development and Technology 2. An Introduction to Two-Piece Hard Capsules and Their Marketing Benefits 3. Hard Shell Capsules in Clinical Trials 4. Capsule Shell Manufacture 5. Non-Gelatin-Based Capsules 6. Hard Shell Capsule Filling Machines 7. Instrumented Automatic Capsule Filling Machines and Filling Machine Simulation 8. Dry-Fill Formulation and Filling Technology 9. Plug Formation 10. Modeling Powder Filling during Encapsulation 11. Scale-Up and Transfer of Hard Shell Formulations across Machine Types 12. Modified-Release Delivery Systems: Extended-Release Capsule Platform 13. Analytical Testing and Evaluation of Capsules 14. Rheological Aspects of Capsule Shell Excipients and the Manufacture of Encapsulated Formulations 15. Quality-by-Design (QbD) for Capsule Formulation and Process Development: Regulatory Science Relevance, Scientific Case Studies, and Future Challenges