Periparturient Diseases of Dairy Cows: A Systems Biology Approach

by Burim N. Ametaj (Editor)

Overview

This book summarizes the results achieved so far by application of various biological systems (including genomics, transcriptomics, proteomics, and metabolomics) involved in the pathomechanisms and early diagnosis of periparturient diseases as specific biomarkers of disease in cattle. These emerging technologies help to extensively enhance our understanding of the etiology and pathogenesis of periparturient diseases of transition dairy cows. The book includes a chapter dedicated to ‘omics’ sciences and one that discusses the myths established in animal and veterinary sciences in recent decades and emerging, new paradigms. The diseases discussed include metritis, mastitis, laminitis, ketosis, rumen acidosis, periparturient immunosuppression, gastrointestinal microbiota and their involvement in disease, infertility, fatty liver, milk fever, and retained placenta. This book is intended for academics, veterinarians, animal nutritionists, researchers, and graduate students working in thefield of ‘omics sciences’ with a special interest in dairy cattle health.

Product Details

ISBN-13:	9783319430331
Publisher:	Springer-Verlag New York, LLC
Publication date:	12/21/2017
Sold by:	Barnes & Noble
Format:	eBook
File size:	2 MB

About the Author

Prof. Dr. Burim N. Ametaj

Department of Agriculture, Food and Nutritional Science

4-10G Agricultural/Forestry Centre

University of Alberta

Edmonton

Canada T6G 2P5

Table of Contents

Introduction.- A. Application of systems biology approach in diagnosis of periparturient disease.- 1. Metritis and fertility in transition dairy cows.- 2. Mastitis in transition dairy cows.- 3. Lameness and laminitis in transition dairy cows.- 4. Fatty liver in transition dairy cows.- 5. Milk fever in transition dairy cows.- 6. Displaced abomasum in transition dairy cow.- B. Application of systems biology approach in identification of screening biomarkers of diseases in transition dairy cows.- 7. Metritis and fertility in transition dairy cows.- 8. Mastitis in transition dairy cows.- 9. Lameness and laminitis in transition dairy cows.- 10. Fatty liver in transition dairy cows.- 11. Milk fever in transition dairy cows.- 12. Displaced abomasum in transition dairy cow.

Editorial Reviews

Reviewer: Tessa Marshall, BVSc, MS, DABVP (University of Illinois College of Veterinary Medicine)
Description: This book introduces the concept of omics and approaching disease in animals not from an individual aspect, but as the effect on a system in the animal. In particular, the book covers the systems biology of periparturient diseases, including ruminal acidosis, laminitis, mastitis, etc.
Purpose: The purpose is to redefine how we describe periparturient diseases and to address their interrelatedness, so that we can better understand and address the health of dairy cows. This book provides an overview of the concepts of a "systems based biology" approach to disease for those who have been trained in the more traditional "component based" approach. The title is a little misleading, as the book does not specifically address periparturient diseases, but summarizes literature that supports the multifactorial nature of these diseases.
Audience: The intended audience is animal science and veterinary science students and faculty studying periparturient diseases. However, a more appropriate audience may be graduate students interested in metabolic disease. The editor has had a career studying bovine periparturient diseases, based on his credentials.
Features: This book provides an introduction to omics — genomics, proteomics, transcriptomics, and metabolomics. It also describes a paradigm shift from looking at diseases at an individual component level, such as a calcium deficiency, to a systems-based approach, such as the transition cow pathobiology. The book is written at a level that requires some understanding of the diseases. Some chapters have summative illustrations with very fine print that is difficult to read.
Assessment: This book is most suitably used as an adjunct to postgraduate studies. It has a lot of information that is not useful in a practical sense to veterinary practitioners, but may be helpful to research scientists.

Doody's Review Service

The intended audience is animal science and veterinary science students and faculty studying periparturient diseases. … This book provides an introduction to omics — genomics, proteomics, transcriptomics, and metabolomics. It also describes a paradigm shift from looking at diseases at an individual component level, such as a calcium deficiency, to a systems-based approach, such as the transition cow pathobiology. … This book is most suitably used as an adjunct to postgraduate studies.” (Tessa Marshall, Doody's Book Reviews, April, 2018)

From the Publisher