Pediatric Nephrology / Edition 7

by Ellis D. Avner, William E. Harmon, Patrick Niaudet, Norishige Yoshikawa, Francesco Emma

Overview

The seventh edition of Pediatric Nephrology, now in three volumes, has been extensively updated and also contains much new material. Its organization flows logically from renal physiology to clinical evaluation. Discussion of the development of kidney structure and function is followed by sections on basic and translational research and on clinical methods, including laboratory tests, diagnostic imaging, and renal pathology. Comprehensive chapters then cover each of the childhood kidney diseases, grouped according to major disease categories. All of these chapters make new genetic information easily understandable for the practitioner and use many algorithms and diagrams to describe appropriate clinical evaluation of symptoms, differential diagnosis, specific diagnostics and currently available therapies. This book, global in perspective, serves as a superb reference and is an invaluable asset during clinical encounters with children having all forms of kidney disease.

Product Details

ISBN-13:	9783662435953
Publisher:	Springer Berlin Heidelberg
Publication date:	11/12/2015
Edition description:	7th ed. 2016
Pages:	2730
Product dimensions:	7.01(w) x 10.00(h) x (d)

About the Author

Ellis D. Avner, MD, is Professor of Pediatrics (Nephrology) and Professor of Physiology at the Medical College of Wisconsin, Milwaukee, USA and Director of the Clinical and Research Polycystic Kidney Disease Program, Children’s Hospital and Health System of Wisconsin. He was also Founding Director of the Children’s Research Institute, Children’s Hospital and Health System of Wisconsin. He has received many awards, including the Henry L. Barnett Award for Excellence in Clinical Care and Education in Pediatric Nephrology from the American Academy of Pediatrics. Dr. Avner has undertaken numerous review and advisory activities, including with the National Institutes of Health and has served on the editorial boards of many leading journals.

William E. Harmon, MD, MA, has recently stepped down from his posts as Chief of the Division of Nephrology at Boston Children’s Hospital, Boston, Massachusetts, USA (a position he took up in 1987) and as Warren E. Grupe Chair in PediatricNephrology. Prior to the latter academic position, Dr. Harmon was Professor of Pediatrics at Harvard Medical School. During his long and distinguished career Dr. Harmon has held many important posts, including President of the American Society of Transplantation, Chairman of the Nation Kidney Foundation and President of the North American Pediatric Renal Transplant Cooperative Study.

Patrick Niaudet, MD, is a Consultant at the Hôpital Necker-Enfants Malades, Paris, France, where he was previously Chairman of Pediatrics and Head of the Pediatric Nephrology Department. In 1986 Dr. Niaudet was appointed Professor of Pediatrics at University Paris-Descartes, Paris. From 2008 to 2011 he served as President of the Société de Néphrologie Pédiatrique and he is also President of the Ethical Committee of the French Biomedical Agency. Dr. Niaudet is Editor for Pediatric Nephrology of “UpToDate” and is a past Assistant and Associate Editor of the

journal.

Norishige Yoshikawa, MD, has, since 2000, been Professor and Chair of Pediatrics at Wakayama Medical University, Wakayama, Japan, having previously been Professor of Health Science at Kobe University School of Medicine. He is current Vice-President of the Japanese Society of Pediatric Nephrology and an ex-Vice President of the Japan Pediatric Society. For the past 15 years he has been a Section Editor for Pediatric Nephrology and he has also served on the editorial board of the Clinical Journal of American Society of Nephrology.

Francesco Emma, MD, is Head of the Department of Nephrology & Urology at Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy, where he also has responsibility for the Nephrology Research Laboratory. Dr. Emma is a member of the Scientific Review Board of the Cystinosis Research Foundation and a board member of the ERA-EDTA Working Group on Inherited Kidney Disorders. In 2012 he served as Chairman of the Scientific Committee for the 2012 meeting of the European Society of Pediatric Nephrology, Krakow, Poland.

Stuart L. Goldstein, MD, is Professor of Pediatrics (affiliated) at University of Cincinnati School of Medicine, Cincinnati, Ohio, USA and is Director of the Center for Acute Care Nephrology at Cincinnati Children’s Hospital Medical Center. In 2013 he won the International “Vicenza” Award in Critical Care Nephrology. He has held numerous positions in professional societies and has served on various journal editorial boards. He is associate editor of Clinical Kidney Disease and is a Pediatric Nephrology section editor for Acute Kidney Injury/Critical Care Nephrology.

Table of Contents

Embryology.- Glomerular Circulation and Function.- Renal Tubular Development.- Perinatal Urology Renal Dysplasia/Hypoplasia.- Syndromes and Malformations of the Urinary Tract.- Sodium and Water: Developmental Physiology and Basic Disorders.- Potassium: Developmental Physiology and Basic Disorders.- Acid-Base Homeostasis: Developmental Physiology and Basic Disorders.- Calcium and Phosphorus: Developmental Physiology.- Disorders of Calcium and Phosphate and Therapy Nutrition: Developmental Physiology and Basic Disorders.- Fluid and Electrolyte Maintenance and Therapy of Basic Disorders (Na/HO/K/Acid Base).- Molecular Biology.- Animal Models.- Clinical Investigation.- Genomic Methods in the Diagnosis and Treatment of Pediatric Kidney Disease.- Renal Stem Cells.- Tissue Engineering.- Clinical Evaluation.- Laboratory Investigation.- Growth and Development.- Diagnostic Imaging.- Renal Pathology.- Congenital Nephrotic Syndrome.- Inherited Glomerular Diseases.- Idiopathic Nephrotic Syndrome: Genetic Aspects.- Idiopathic Nephrotic Syndrome: Clinical Aspects.- Immune Mediated Glomerular Injury.- Complement Mediated Glomerular Injury.- Acute Postinfectious Glomerulonephritis.- Immunoglobulin A Nephropathies (includes HSP).- Membranoproliferative and C3-Mediated GN.- Membranous Nephropathy.- Nephronophthisis-Medullary Cystic Kidney Disease.- Polycystic Kidney Disease.- Animoaciduria and Glycosuria.- Tubular Disorders of Electrolyte Regulation.- Renal Tubular Acidosis.- Nephrogenic Diabetes Insipidus.- Cystinosis.- Fanconi Syndrome.- Primary Hyperoaxaluria.- Tubulointerstitial Nephritis.- Vasculitis.- Systemic Lupus Erythematosis.- HUS.- Sickle Cell Nephropathy.- Diabetic Nephropathy.- Renal Manifestations of Metabolic Disorders.- Infectious Diseases and the Kidney Nephrotoxins.- Urinary Tract Infections.- Vesicoureteral Reflux and Scarring.- Obstructive Uropathy.- Bladder Dysfunction.- Urolithiasis.- Pediatric Renal Tumors.- Epidemiology of Hypertension.- Pathophysiology ofHypertension.- Evaluation of Hypertension in Childhood Diseases.- Management of the Hypertensive Child.- Pathogenesis of Acute Renal Failure.- Evaluation and Management of Acute Kidney Injury.- Pathophysiology of Progressive Renal Disease.- Management of Chronic Kidney Disease.- Handling of Drugs in Children with Abnormal Renal Function.- Endocrine and Growth Abnormalities.- Chronic Kidney Disease Mineral and Bone Disorder.- Peritoneal Dialysis.- Hemodialysis.- Transplantation Immunology.- Pediatric Renal Transplantation.- Immunosuppression.- Complications of Renal Transplantation.- IPNA: Global Pediatric Nephrology, Introduction and Overview.- AFPNA.- ALANEPE.- AsPNA.- ASPN.- ANZPNA.- ESPN.- JSPN.

Editorial Reviews

3 Stars from Doody

This is a comprehensive reference on congenital and acquired kidney diseases and their therapies in children. This edition has been significantly reorganized and offers an important emphasis on the role of genetics in pediatric kidney diseases. When compared to adults, children are afflicted with a unique range of diseases and abnormalities, as well as requirements for care. This book is an attempt to address those unique pediatric aspects of nephrology. The audience is pediatric nephrologists, adult nephrologists, pediatric and adult urologists, and to a lesser extent, pediatricians. It will be an essential reference for nephrology fellows. The fourth edition of this text has been reorganized and reoriented to emphasize genetics and the latest renal replacement therapies. Sections on basic embryology and physiology are excellent, as are chapters on research methodology. Although there is some variation between chapters, the overall quality is extremely high. Chapters addressing glomerular disorders are particularly well written. A new chapter addresses the intensive care management of children with life threatening complications of renal disease. Minor concerns are a few poorly focused concluding chapters on regional aspects of renal disease. Also, the binding is of poor quality. This is the premiere reference text on pediatric nephrology available today. The editors are to be congratulated for continuing to add significant improvements to the text without expanding its length.

F. Bruder Stapleton

Shorter, lighter, and more condensed, this fourth edition reflects advances in the understanding of the molecular basis of renal disease and in the management of end-stage renal failure. The first section describes the developmental biology of the kidney and summarizes the current understanding of renal physiology. Subsequent sections cover the homeostatic role of the kidney; research techniques; the way in which the child with renal disease presents and is investigated; details of congenital renal malformations and the whole gamut of genetically determined disorders; glomerular diseases; vascular and interstitial diseases; urinary tract disease; the relationship between the kidneys and blood pressure; special clinical problems; acute renal injury; chronic renal failure; and reports from around the world. Annotation c. Book News, Inc., Portland, OR (booknews.com)

Booknews

Aus den Rezensionen zur 6. Auflage:

“... Der Text ist aktuell und sehr klar und präzise formuliert, sodass er sowohl vom jungen Arzt in der kindernephrologischen Sprechstunde als auch vom erfahrenen Kindernephrologen geschätzt wird. Embryologische, pathophysiologische und anatomische Erklärungen werden durch konkrete und praxisnahe Ernpfehlungen zu Diagnostik und Therapie ergänzt. ... Insgesamt haben wir einen eindeutig positiven Eindruck: die sechste Auflage des ‘Avner’s Pediatric Nephrology’ ist ein empfehlenswertes Nachschlagewerk für Kindernephrologen und kindernephrologisch- interessierte Fachärzte.“ (Giacomo Simonetti, in: Pädiatrie up2date, December/2010, Issue 4)

From the Publisher