Pediatric CNS Tumors

by Nalin Gupta (Editor), Anuradha Banerjee (Editor), Daphne Haas-Kogan (Editor)

Overview

Pediatric CNS Tumors is a detailed review of childhood nervous system tumors with a particular emphasis on biological data and treatment algorithms for each tumor type. Additional detailed information is provided on the recent advances in chemotherapy, radiation and surgery for these tumors.

Product Details

ISBN-13:	9783662092279
Publisher:	Springer-Verlag New York, LLC
Publication date:	03/09/2013
Series:	Pediatric Oncology
Sold by:	Barnes & Noble
Format:	eBook
File size:	20 MB
Note:	This product may take a few minutes to download.

About the Author

Nalin Gupta, MD, PhD is Professor of Neurological Surgery at the University of California San Francisco, and Chief of the Division of Pediatric Neurosurgery at UCSF Benioff Children’s Hospital. Dr. Gupta received his MD from the University of Toronto, and his PhD in biophysics at UCSF. He completed his neurosurgery training at the University of Toronto and a pediatric neurosurgery fellowship at the Hospital for Sick Children, also in Toronto, Canada. His current research interests include the role of inflammatory cytokines in the progression of brain tumors, and fetal surgery for congenital spine disorders. He leads a number of translational surgical clinical trials evaluating new therapies for brainstem tumors, and congenital disorders of metabolism.

Daphne A. Haas-Kogan, MD, is chair of the Department of Radiation Oncology at Brigham and Women’s Hospital, Dana-Farber Cancer Institute, and Boston Children’s Hospital, Boston, USA. She is a Professor ofRadiation Oncology at Harvard Medical School. Dr. Haas-Kogan gained her undergraduate degree in Biochemistry and Molecular Biology magna cum laude from Harvard University. She received her MD from the University of California, San Francisco and was elected to the Alpha Omega Alpha Medical Honor Society. After completing a residency in Radiation Oncology and post-doctoral fellowship in Molecular Neuro-oncology at UCSF, she remained there as a tenure track faculty member with joint appointments in Radiation Oncology and Neurological Surgery, becoming Vice-Chair for Research in 2003 and Educational Program Director in 2008. Dr. Haas-Kogan has been selected as one of the top physicians in the United States by various publications. She continues to lead and perform laboratory research, design clinical trials, establish robust collaborations with neuro-pathologists, neuro-oncologists, and neuro-radiologists, and develop a thriving clinical practice in radiation oncology.

Table of Contents

Tumors by Pathological Type: Supratentorial Gliomas. Low grade astrocytomas. Malignant astrocytomas. Optic pathway gliomas.- Cerebellar Astrocytoma.- Brainstem Glioma. Diffuse pontine glioma. Dorsally exophytic glioma. Cervico-medullary astrocytoma.- Ependymoma.- Primitive neuroectodermal tumors. Supratentorial PNET. Medulloblastoma. Atypical rhabdoid/teratoid tumors.- Germ Cell Tumors. Germinoma. Choriocarcinoma. Yolk cell tumor. Teratoma.- Craniopharyngioma.- Neuronal Tumors. Ganglioglioma. DNET.- Choroid Plexus Tumors.- Intramedullary Spinal Cord Tumors. Ependymoma. Astrocytoma.- Neurocutaneous Syndromes. NF. Tuberous sclerosis. Von Hippel-Lindau. Ataxia telangiectasia.- Advances in Management: Diagnostic Imaging. Functional MRI. MR spectroscopy. Diagnosis of radiation necrosis.- Surgery. Brain mapping for dominant hemisphere tumors. Posterior fossa tumors. Spinal cord tumors. Special considerations in infants.- Chemotherapy.- Radiation Therapy.- Treatment Algorithms.- Chemotherapy Schedules.

Editorial Reviews

Reviewer: Robert M Arensman, MD (University of Illinois at Chicago College of Medicine)
Description: This is an update of a 2004 compendium of childhood central nervous systems tumors with standard, current information on the diagnosis and treatment of these malignancies.
Purpose: The editors seek to "provide a current, biologically-based perspective of the management of central nervous system tumors in children." Since brain tumors are second in occurrence only to the leukemias and lymphomas, this is a significant and important volume of knowledge for all those caring for children. The editors with 29 writers achieve the goal in a handsome book of 350 pages.
Audience: The book is sufficiently detailed to be valuable to experts in the field, but it also will appeal to anyone caring for children afflicted with these tumors as a general reference. However, the obvious limited scope means limited readership, specifically in the fields of pediatrics, pediatric neurosurgery, and pediatric oncologists. The editors all work at the University of California San Francisco and most contributors are members of the section at that institution.
Features: The first 12 of the book's 17 chapters follow a similar format. The tumors are divided by histopathology, and within each chapter at least six sections review epidemiology, histopathology, clinical features, diagnosis and imaging, treatment, and outcome. Each section is numbered, making it easy to follow and easy to compare from chapter to chapter. The final five chapters are devoted to neuroimaging, current surgical management, chemotherapy, radiation therapy, and late effects. Obviously, these chapters do not lend themselves to a similar format, but are complete, well done, and current. The book is highly illustrated with imaging studies, photographs, photomicrographs, charts, and diagrams (some in color), all well reproduced.
Assessment: This is a nice update in a highly important area of pediatric tumor care. It is quite well done, complete, and easy to read. It is a valuable addition to the current books on childhood neurosurgery care.

Doody's Review Service

This volume written by authors of the University of California in San Francisco and Aukland, review in 17 chapters the updated knowledge on pediatric brain tumors, their clinic, diagnosis, therapy and outcome. Clearly written, each chapter has many references. … For pediatricians, pediatric neurologists, neurosurgeons and pediatric endocrinologists.” (Pediatric Endocrinology Reviews (PER), vol. 14 (3), March, 2017)

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