Pathway Analysis and Optimization in Metabolic Engineering

by Néstor V. Torres, Eberhard O. Voit

Overview

This book introduces researchers and advanced students in biology and engineering to methods of optimizing biochemical systems of biotechnological relevance. It examines the development of strategies for manipulating metabolic pathways, demonstrates the need for effective systems models, and discusses their design and analysis, while placing special emphasis on optimization. The authors propose power-law models and methods of Biochemical Systems Theory toward these ends. All concepts are derived from first principles, and the text is richly illustrated with numerous graphs and examples throughout.

Product Details

ISBN-13:	9780521177481
Publisher:	Cambridge University Press
Publication date:	04/28/2011
Pages:	324
Product dimensions:	6.70(w) x 9.60(h) x 0.70(d)

Table of Contents

Preface; 1. Target: a useful model; 2. Methods of biochemical systems theory; 3. A model of citric acid production in the mold Aspergillus niger; 4. Optimization methods; 5. Optimization of biochemical systems; 6. Optimization of citric acid production in Aspergillus niger; 7. Maximization of ethanol and carbohydrate production in Saccharomyces cerevisiae; 8. Conclusions; Author index; Subject index.