Papillomaviruses in Human Cancer: The Role of E6 and E7 Oncoproteins

by Massimo Tommasino

Overview

Human Papillomavirus has been associated with cancer of the anogenital tract, oral cavity and skin. Two early viral proteins, E6 and E7, play a key role in the malignant transformation of the cell. This book covers different aspects of these two viral oncoproteins. In particular, it focuses on their mechanism in the induction of cellular proliferation and malignant transformation.

Product Details

ISBN-13:	9781475761290
Publisher:	Springer US
Publication date:	04/15/2013
Edition description:	Softcover reprint of the original 1st ed. 1997
Pages:	173
Product dimensions:	5.98(w) x 9.02(h) x 0.02(d)

Table of Contents

1. Human Papillomaviruses and Cancer: A Retrospective.- 2. Regulation of E6 and E7 Oncogene Transcription.- 3. E6 Protein.- 4. E7 Protein.- 5. Immunological Aspects of the E6 and E7 Oncogenes: Tools for Diagnosis and Therapeutic Intervention.