The AMY disease outbreak has wiped out a majority of the population, making most of the world insane and those infected act like monsters. Jackie Ellis has managed to survive for six years with the help of her friend, Chance York, and together they have worked as a team to protect each other and stay alive. However when a mysterious boy with unsettling secrets, Tristan, comes to their city with news of a developing cure, Chance makes assisting Tristan a priority over his plans with Jackie.
When they finally arrive to the research program called HEAD, everything is not as it seems. Jackie learns the hidden secrets of the developing cure, and as time passes by, insanity begins to grow within the walls of the laboratory. HEAD is violent and unpredictable, and Jackie is convinced that she wants out. However, her love for Chance and her dedication to save the world compels her forward.
One Last Chance follows Jackie on her intense and emotional journey of surviving apocalyptic chaos and discovering the cure to save the world, while all along developing an impressible romance with Chance.
