Table of Contents
PREFACE ix
CONTRIBUTORS xi
PART I APPLICATIONS OF OLEFIN METATHESIS REACTIONS 1
Section I INTRODUCTION 3
1 Olefin Metathesis Reactions: From a Historical Account to Recent Trends 5 Didier Astruc
Section II TYPES OF OLEFIN METATHESIS REACTIONS 37
2 Cross Metathesis 39 Karolina Żukowska and Karol Grela
3 Ring-Closing Metathesis 85 Bianca J. van Lierop, Justin A. M. Lummiss, and Deryn E. Fogg
4 Ene-Yne Metathesis 153 Steven T. Diver and Justin R. Griffiths
5 Domino and Other Olefin Metathesis Reaction Sequences 187 Bernd Schmidt and Stefan Krehl
6 Enantioselective Olefin Metathesis 233 Brice Stenne and Shawn K. Collins
7 Olefin Metathesis Polymerization 269 Astrid-Caroline Knall and Christian Slugovc
Section III APPLICATIONS OF OLEFIN METATHESIS REACTIONS 285
8 Applications in the Synthesis of Natural and Biologically Active Molecules 287 Janine Cossy
9 Multifold Ring-Closing Olefin Metatheses in Syntheses of Organometallic Molecules with Unusual Connectivities 311 Tobias Fiedler and John A. Gladysz
10 Industrial Applications of Olefin Metathesis Polymerization 329 Christian Slugovc
11 Commercial Potential of Olefin Metathesis of Renewable Feedstocks 335 Andrew Nickel and Richard L. Pederson
12 Challenges and Opportunities for Scaling the Ring-Closing Metathesis Reaction in the Pharmaceutical Industry 349 Keith R. Fandrick, Jolaine Savoie, Nathan Yee, Jinhua J. Song, and Chris H. Senanayake
PART II DEVELOPMENT OF THE TOOLS 367
Section IV DIFFERENT CLASSES OF OLEFIN METATHESIS CATALYSTS 369
13 Well-Defined Olefin Metathesis Catalysts Based on Metals of Group 4–7 371 Cezary Pietraszuk
14 Ruthenium-Benzylidene Olefin Metathesis Catalysts 397 Georgios C. Vougioukalakis
15 Ruthenium-Indenylidene and Other Alkylidene Containing Olefin Metathesis Catalysts 417 César A. Urbina-Blanco, Stefano Guidone, Steven P. Nolan, and Catherine S. J. Cazin
16 Hoveyda-Type Olefin Metathesis Complexes 437 Yakov Ginzburg and N. Gabriel Lemcoff
17 Schiff Base Catalysts and Other Related Latent Systems for Polymerization Reactions 453 Yohann Morin and Régis M. Gauvin
Section V DEVELOPMENT OF CONCEPTS IN OLEFIN METATHESIS CATALYSTS 473
18 Novel Concepts in Catalyst Design—a Case Study of Development of Hoveyda-Type Complexes 475 Michał Barbasiewicz
19 Theoretical Attempts: “In Silico Olefin Metathesis”—How Can Computers Help in the Understanding of Metathesis Mechanisms and in Catalysts Development? 483 Albert Poater, Laura Falivene, and Luigi Cavallo
20 Immobilization of Olefin Metathesis Catalysts 495 Michael R. Buchmeiser
21 Olefin Metathesis inWater and Aqueous Media 515 Bruce H. Lipshutz and Subir Ghorai
22 Olefin Metathesis in Green Organic Solvents and Without Solvent 523 Christian Bruneau and Cédric Fischmeister
23 Olefin Metathesis in Fluorous Phases and in Fluorinated Aromatic Solvents 537 Cezary Samojłowicz, Anna Kajetanowicz, and Karol Grela
24 Olefin Metathesis in Ionic Liquids 547 Pierre Queval, Mathieu Rouen, Annie-Claude Gaumont, Isabelle Dez, Olivier Baslé, and Marc Mauduit
25 Purification Strategies in Olefin Metathesis 559 Krzysztof Skowerski and Łukasz Gułajski
PART III TABLES AND CHARTS 573
Section VI OLEFIN METATHESIS CATALYSTS—A TABULAR REVIEW 575 Łukasz Wo´zniak, Grzegorz Zielinski, and Karol Grela
Outlook and Perspectives 587
INDEX 589