Nutrients and Epigenetics / Edition 1

by Sang-Woon Choi, Simonetta Friso

Overview

Explores the Newly Discovered Link Between Nutrition and Epigenetics

Current research suggests that nutrients are more than just food components and that certain nutrients can impact the expression of genes that lead to the development of chronic diseases. With contributions from experts in both fields, Nutrients and Epigenetics examines the epigenetic phenomena and the fascinating implications of diet on this largely uncharted field.

Generously laden with tables and illustrations, many in color, this book addresses how nutrients alter physiologic and pathologic processes in the human body through epigenetic changes without affecting the DNA sequence. It also explains the detailed molecular structures of epigenetic phenomena and closely examines the current knowledge surrounding the biology of aging and embryonic growth regulation.

Assesses the Likelihood of Clinical Applicability

In one single compendium, this resource delineates the nutritional factors that further much-studied aberrant epigenetic patterns, such as DNA methylation, histone modifications, and chromatin remodeling. The book spotlights the influence of nutrition on epigenetic gene regulation, opening the way for counteracting future disease processes associated with epigenetic phenomena—a step that could potentially change the face of disease prevention and development.

Product Details

ISBN-13:	9780367385644
Publisher:	Taylor & Francis
Publication date:	10/21/2019
Pages:	258
Product dimensions:	6.12(w) x 9.19(h) x (d)

About the Author

Sang-Woon Choi, MD, PhD, Tufts University, Boston, Massachusetts, USA

Simonetta Friso, MD, PhD, University of Verona, Italy

Table of Contents

Preface vii

The Editors ix

Contributors xi

Chapter 1 Introduction Simonetta Friso Sang-Woon Choi 1

Chapter 2 Methylation on the nucleosome Da Jia Xiaodong Cheng 7

Chapter 3 Mammalian DNA methyltransferases Michael J. Boland Judith K. Christman 37

Chapter 4 Chromatin remodeling and histone modifications Gavin R. Schnitzler 67

Chapter 5 Nutrients and DNA methylation Sang-Woon Choi Roberto Corrocher Simonetta Friso 105

Chapter 6 Nutrients, histone modifications, and chromatin remodeling in chronic inflammation Barbara Delage Roderick H. Dashwood 127

Chapter 7 Nutrients, epigenetics, and embryonic development Craig A. Cooney 155

Chapter 8 Nutrition, epigenetics, and aging John C. Mathers Dianne Ford 175

Chapter 9 Nutrition, epigenetics, and cancer Sharon A. Ross 207

Chapter 10 Conclusions and future perspectives Sang-Woon Choi Simonetta Friso 229

Index 233

What People are Saying About This

From the Publisher

Overall, the volume does an important service by unraveling, in a systematic way, the importance of nutrition and specific nutrients in the regulation of epigenetic processes. ...What is our responsibility as parents in establishing the health of our children even during pregnancy? How can children's diets today influence them, and also their children, over many years from now? The answers to these questions, and also many others, may well lie between the covers of this book.
—American Journal of Human Biology, 2010

Editorial Reviews

Overall, the volume does an important service by unraveling, in a systematic way, the importance of nutrition and specific nutrients in the regulation of epigenetic processes. ...What is our responsibility as parents in establishing the health of our children even during pregnancy? How can children's diets today influence them, and also their children, over many years from now? The answers to these questions, and also many others, may well lie between the covers of this book.
—American Journal of Human Biology, 2010

From the Publisher