NANOTHERANOSTICS FOR PERSONALIZED MEDICINE

NANOTHERANOSTICS FOR PERSONALIZED MEDICINE

NANOTHERANOSTICS FOR PERSONALIZED MEDICINE

NANOTHERANOSTICS FOR PERSONALIZED MEDICINE

eBook

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Overview

The application of nanotechnology in the biomedical field, known as nanomedicine, has gained much interest in the recent past as a versatile strategy for selective drug delivery and diagnostic purposes. The nanotheranostic approach, which aims to combine both therapeutic and imaging/diagnostic functionalities, is characterized by a strong pluridisciplinarity where the chemistry of materials, bioconjugate chemistry, pharmaceutical technology, drug delivery, imaging, and pharmacology, work together. Nanotheranostics combine simultaneous non-invasive diagnosis and treatment of diseases with the exciting possibility to monitor drug release and distribution in real time; thus offering the opportunity to optimize treatment outcomes in cancer and other severe diseases. Clinical applications of nanotheranostics would enable earlier detection and treatment of diseases, and earlier assessment of the response, thus allowing to identify patients which would potentially respond to therapy and have higher possibilities of a favorable outcome.Nanotheranostics for Personalized Medicine presents an integrated and transdisciplinary description of nanotheranostics. It provides principles of imaging techniques and concrete examples of advances and challenges in the development of nanotheranostics for personalized medicine.This book is written for students (Bachelors to Doctoral level) as well as experienced researchers, in academia or the industry, interested in this emerging concept in the nanomedicine field.

Product Details

ISBN-13: 9789814713542
Publisher: World Scientific Publishing Company, Incorporated
Publication date: 02/22/2016
Sold by: Barnes & Noble
Format: eBook
Pages: 348
File size: 9 MB

Table of Contents

Preface vii

Chapter 1 Combining Imaging and Drug Delivery for the Treatment of Severe Diseases Simona Mum Patrick Couverur 1

Chapter 2 Increased Sensitivity for Medical Imaging Using Non-Ionizing Nanomedicine as Contrast Agents Cyrille Richard Bich-Thuy Doan Nathalie Mignet 7

Chapter 3 MRI T2 Weighted Theranostic Nanodeviccs and Chemotherapy Sophie Laurent Luce Vander Elst Dimitri Stanicki Robert N.Muller 45

Chapter 4 MRI T1 Weighted Theranostic Nanodcvices Lucie Sancey François Lux Géraldine Le Duc Sabin Carme Olivier Tillement 67

Chapter 5 Optical Imaging and Chemotherapy Guillaume Bort Simona Mura Patrick Couvreur 83

Chapter 6 Plasmonic Nanoparticles-Coated Microbubbles for Theranostic Applications Mark A. Borden Jacob D. Dove Todd W. Murray 115

Chapter 7 Contribution of Nuclear Medicine to Cancer Nanotheranostics Thomas Lars Andresen Anncatrine L. Petersen Anders E. Hansen Jonas R. Henriksen 147

Chapter 8 Nanotheranostics in Gene Therapy Madhura Deshpande Shravan Kumar Sriraman Vladimir Torchilin 191

Chapter 9 Nanotheranostics in Cardiovascular Diseases Maya Juenet Mariana Varna Cedric Chauvierre Didier Letoumeur 223

Chapter 10 Stimuli-Responsive Nanothcranostics Basit Jameen Jun Wu Critian Vilos Andrew Whyte David Werstler Lori Pollit Omid G. Farokhzad 267

Chapter 11 Advancing the Practical Clinical Utility in Personalized Medicine: Capabilities and Lessons Learned for Pharmacology and Pharmaceutics Ioannis S. Vizirianakis Christina Karavasili Elsa P. Amanatiadou Dimitrios G. Fatouros 297

Editors' Biographies 325

Contributors 327

Index 333

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