Nanocarriers for Drug-Targeting Brain Tumors

by Lalit Kumar PhD (Editor), Yashwant Pathak PhD. (Editor)

Overview

Nanocarriers for Drug-Targeting Brain Tumors covers different types of nanocarriers and  their design and development for targeting drugs to the brain. The book also presents case studies and the mechanism of action of nanocarriers in drug targeting to a specific site. This helps researchers and clinicians understand the design, development and mechanism of action of nanocarriers. As brain tumors continue to be a significant health problem globally, and very complex for targeting drugs, conventional dosage forms are not very effective and side-effects are a major concern. Functionalized nanocarriers can address these problems.

Furthermore, the targeting of nanocarriers is preferred for reducing toxicity and improving the effectiveness of the drugs. However, there is a need for understanding the design and development of formulation with the mechanism of action of nanocarriers for brain targeting.

Product Details

ISBN-13:	9780323907736
Publisher:	Elsevier Science
Publication date:	06/23/2022
Series:	Micro and Nano Technologies
Pages:	856
Product dimensions:	7.50(w) x 9.25(h) x 1.71(d)

About the Author

Lalit Kumar, is Assistant Professor in the Department of Pharmaceutics, at Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, India. His area of research includes the development of nanocarriers for drug-targeting tumor cells in the colon, brain, breast, and lung.

Yashwant Pathak, is Professor and Associate Dean for the Faculty Affairs at the College of Pharmacy, at the University of South Florida. Tampa, USA. His area of research is in health care education, nanotechnology, drug delivery systems and nutraceuticals.

Table of Contents

Part A Anatomy and physiology of the brain 1. An overview of the anatomy and physiology of the brain 2. Blood-brain barrier and central nervous system drug delivery: Opportunities and challenges Part B Pharmacological and clinical problems 3.Challenges in targeting to brain and brain tumors 4. Potential targeting sites in brain and brain tumors 5. Drug resistance problems in chemotherapy Part C Introduction and biomedical applications of nanocarriers 6. An overview on nanocarriers 7. Biomedical applications of nanocarriers in brain tumor targeting Part D Lipophilic nanocarriers 8. Solid lipid nanoparticle-based drug delivery for targeting brain tumors 9. Nanostructured lipid carriers as an alternative carrier with high drug loading for targeting to brain tumors 10. Design, development, and mechanism of liposomes in drug targeting to brain tumors 11. Niosomes based drug delivery in targeting brain tumors 12. Nanoemulsions as effective carriers for targeting brain tumors Part E Polymeric nanocarriers 13. Mechanism of polymeric micelles for drug targeting to brain tumors 14. Dendrimers as carriers for active targeting of brain tumors 15. Multifunctional polymeric nanocarriers for targeting and treatment of brain tumors 16. Polymersomes for targeting to brain tumors Part F Metallic nanocarriers systems 17. Development and applications of gold nanoparticles for drug targeting to brain tumors 18. Gold nanoparticles in cancer theranostics 19. Targeting of silver nanoparticles to brain tumors Part G Hybrid nanocarriers 20. Hybrid nanoparticles to cross the blood–brain barrier 21. Targeting of lipid-polymer (hybrid) nanoparticles to brain tumors 22. Nano-enabled systems for neural tissue regenerative applications 23. Multifunctional liposome-quantum dot hybrid nanocarriers for drug targeting to brain tumors 24. Drug-loaded nanoclusters for brain targeting 25. Nano-enabled platforms for tropical diseases affecting the CNS 26. Phytoconstituents in brain delivery using nanodrug delivery 27. Multifunctional nanocarrier systems targeting brain tumors: A review Part H Future directions and toxic concerns 28. Expert opinion on current challenges and future directions related to nanocarriers for drug targeting to the brain 29. Biological nanodrugs for brain targeting

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From the Publisher

Provides information on the major nanomaterial types used for drug targeting and delivery to combat brain tumors