Mirroring History of the "Russian Flu": Infectomic Decoding of Covid-19

by Victor S Huang

Overview

The “Russian Flu” was the biggest human CoV disease pandemic in the history before the ongoing global pandemic of COVID-19 occurred. The causative CoV agent, OC43, of “Russian Flu” was finally revealed in 2005 by infectomics-based molecular clock analysis. To date, the COVID-19 pandemic has challenged public health systems globally, raising various dilemmas or controversial issues that include the origin of virus, cross-species transmission to humans, intervention measures, and various impacts related to the ecologic and evolutionary aspects of viral infections. The future of SARS-CoV-2 transmission will mainly depend on the duration of immunity, and the degree of cross-immunity between SARS-CoV-2 and other HCoVs. While most research on host-pathogen interactions has only explored medical aspects of herd immunity, much less attention has been paid to evolutionary and ecological aspects of immunity (ecoimmunity) against infectious diseases, including COVID-19. This ebook will focus on mirroring the past and decoding of COVID-19 using the infectomic approaches.
Chapter one is to introduce the coronavirus disease issue to be explored. Chapter two is about infectomic identification of the causative agent of the “Russian Flu” outbreak in 1889. It may yield new insight into the origin of SARS-CoV-2. Chapter three states the issue of ecoimmunity that is a missing link to the major scientific dilemma of COVID-19. Chapter four discusses the roles of exosymbiosis-endosymbiosis balance (EESB) and ecohealth in COVID-19. Chapter five is a summary of this ebook. SARS-CoV-2 may eventually become a new HCoV (No. 5) that is persistently circulating in humans and causes common cold in a way similar to OC43.

Product Details

BN ID:	2940164981501
Publisher:	Victor S Huang
Publication date:	08/06/2021
Sold by:	Smashwords
Format:	eBook
File size:	127 KB

About the Author

Professor Victor S Huang (MD, PhD) is a biomedical scientist, trained as an expert in molecular pharmacology and microbial infections in the United States. As a Faculty member and Principal Investigator he used to work at University of Southern California Children’s Hospital Los Angeles. He is currently a Visiting Professor at Guangzhou Medical University, China. He was a recipient of the First Class Prize for Science and Technology awarded by the Ministry of Health, China, in 1989. Dr. Huang has coined the concept of infectomics and proposed a new theory that the exo-endo symbiotic balance (EESB) is critical for maintaining the host homeostasis and that the exo-endo symbiotic imbalance (EESI) mainly contributes to the pathogenesis of microbial infections, including HIV/SIV and CoVs. His first book on holo-omics studies on microbial infections (Infectomics) was published in 2020.