This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson's Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration.
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Leucine-Rich Repeat Kinase 2 (LRRK2)
This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson's Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration.
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Leucine-Rich Repeat Kinase 2 (LRRK2)
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Leucine-Rich Repeat Kinase 2 (LRRK2)
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Product Details
ISBN-13: | 9783319499697 |
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Publisher: | Springer-Verlag New York, LLC |
Publication date: | 03/28/2017 |
Series: | Advances in Neurobiology , #14 |
Sold by: | Barnes & Noble |
Format: | eBook |
Pages: | 271 |
File size: | 1 MB |
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