From the author of The Epigenetics Revolution ("A book that would have had Darwin swooning."--Guardian) comes a lucid and engaging report from the cutting edge of genomic biology.
Nessa Carey is a visiting professor at Imperial College, London. She earned her Ph.D. in virology from the University of Edinburgh. Having worked in the biotech and pharmaceutical industries for more than a decade, she maintains strong relationships with leading researchers in Europe and across the United States, at such institutions as the Harvard Medical School, the University of Pennsylvania, the Wistar Institute, the MD Anderson Cancer Center, and the University of Southern California. Carey is also the author of The Epigenetics Revolution: How Modern Biology Is Rewriting Our Understanding of Genetics, Disease, and Inheritance.
Table of Contents
Acknowledgments Notes on Nomenclature An Introduction to Genomic Dark Matter 1. Why Dark Matter Matters 2. When Dark Matter Turns Very Dark Indeed 3. Where Did All the Genes Go? 4. Outstaying an Invitation 5. Everything Shrinks When We Get Old 6. Two Is the Perfect Number 7. Painting with Junk 8. Playing the Long Game 9. Adding Colour to the Dark Matter 10. Why Parents Love Junk 11. Junk with a Mission 12. Switching It On, Turning It Up 13. No Man's Land 14. Project ENCODE—Big Science Comes to Junk DNA 15. Headless Queens, Strange Cats, and Portly Mice 16. Lost in Untranslation 17. Why LEGO Is Better Than Airfix 18. Mini Can Be Mighty 19. The Drugs Do Work (Sometimes) 20. Some Light in the Darkness Notes Appendix: Human Diseases in Which Junk DNA Has Been Implicated Index